Rex MD vs NextMeds
An in-depth comparison of two leading GLP-1 Providers
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Rex MD
Best for: coverage in all 50 states, which most of the register will not confirm
Visit Rex MD →
NextMeds
Best for: semaglutide at $79/month, 59% under the register median
Visit NextMeds →Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, NextMeds opens cheaper — $79/mo against $349, and NextMeds finishes ahead, 9.2 to 7.9. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
Rex MD
NextMeds
Compounded Semaglutide Membership, drug included when prescribed, alongside telehealth visits, a care coach, a dietitian and shipping. $79 is the month-to-month rate read from the pricing section on 2026-08-14. The site headline reads 'from $49/mo': that is the 12-month prepaid term divided down, not a monthly price, and the ladder between them is 3-month $76, 6-month $73, 12-month $49. A summer promotion was running with a stated end of August 20, so $79 may itself be discounted.
Compounded Tirzepatide Membership, drug included when prescribed, alongside telehealth visits, a care coach, a dietitian and shipping. $109 is the month-to-month rate read from the pricing section on 2026-08-14. The advertised 'GLP-1 + GIP: $95' is the 12-month prepaid term divided down; the ladder is 3-month $105, 6-month $100, 12-month $95. A summer promotion was running with a stated end of August 20, so $109 may itself be discounted.
What’s included
Rex MD
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
NextMeds
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Rex MD
7.9/10
NextMeds
9.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Rex MD | NextMeds |
|---|---|---|
| Starting Price | $349/mo | ✓$79/mo |
| Features | 8 features | 8 features |
| States Available | 50 | 50 |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About Rex MD
The program is a flat monthly charge of about $199, which takes in the medical intake, consultations with a provider, the prescribed drug, syringes and overnight shipping at no cost; Zepbound vials start at around $349 per month. Rex MD belongs to LifeMD, aims at men's health, and runs its weight-management program 100 percent online, prescribing brand-name semaglutide and Zepbound (tirzepatide) vials that partner pharmacies fill. Its clinicians are US-based and licensed by state, LegitScript certifies the platform, all 50 states are served, and no insurance is billed.
Read our full Rex MD review →About NextMeds
Membership is a single flat monthly charge, and inside it sit free shipping, a registered dietitian holding a license, a care coach working 1:1, telehealth visits and the drug itself where one is prescribed. Insurance is not billed. A free assessment online goes to a licensed provider, who adds a phone or video consult in states that demand one, then prescribes if it fits. Compounding pharmacies within the Next Meds network, all licensed, ship. Auto-renewal does not exist, cancellation is open, and all 50 states can order compounded tirzepatide and semaglutide.
Read our full NextMeds review →Pros & Cons
Rex MD
What we like
- Semaglutide at $199 a month, 85% below the $1299 median for the same drug and form across this register
- Tirzepatide at $349 a month, 72% below the $1249 median for the same drug and form across this register
- The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
- The monthly figure covers medication, consult, shipping
- Coverage is published for all 50 states
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- No price appears until the medical intake is complete, so the cost cannot be compared before health information is submitted
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
NextMeds
What we like
- Semaglutide at $79 a month, 58% below the $189 median for the same drug and form across this register
- Tirzepatide at $109 a month, 59% below the $267 median for the same drug and form across this register
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
- The monthly figure covers medication, consult, shipping, coaching
- Coverage is published for all 50 states
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
NextMeds takes it, 9.2 against 7.9, and it is especially strong on semaglutide at $79/month, 59% under the register median. Rex MD is no weak second and may fit you better on coverage in all 50 states, which most of the register will not confirm.
Choose Rex MD if…
You want coverage in all 50 states, which most of the register will not confirm and an opening price near $349 a month.
Choose NextMeds if…
You want semaglutide at $79/month, 59% under the register median and an opening price near $79 a month.
Ready to start? Vetted GLP-1 providers
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SkinnyRx
Starting below a standard dose, with microdose tiers
From $149.25/mo
Get started →YourEra
Semaglutide at $99/month, 63% under the register median
From $99/mo
Get started →Gala
Moving between compounded and brand without changing seller
From $129/mo
Get started →Rex MD vs NextMeds: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.