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PreventiveMD vs He & She MD

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
PreventiveMD logo

PreventiveMD

7.4
★★★3.7/5

Best for: oral orforglipron alongside the injectables

Visit PreventiveMD
VS
He & She MD logo

He & She MD

9.3
★★★★4.7/5

Best for: starting below a standard dose, with microdose tiers

Visit He & She MD

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, PreventiveMD opens cheaper — $83/mo against $99, and He & She MD finishes ahead, 9.3 to 7.4. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

PreventiveMD

StartingCompounded
$83/mo
semaglutide

'As low as $83/mo, all-in' — homepage price, live-verified 2026-07-10

StartingCompounded
$97/mo
tirzepatide

'As low as $97/mo, all-in' — homepage price, live-verified 2026-07-10

Wegovy (brand)Brand-name
$149/mo
semaglutide

Medication starts at $149/mo; a separate $49/mo membership fee applies to brand plans

Foundayo (brand)Brand-name
$149/mo
orforglipron

Medication starts at $149/mo; a separate $49/mo membership fee applies to brand plans

Zepbound (brand)Brand-name
$299/mo
tirzepatide

Medication starts at $299/mo; a separate $49/mo membership fee applies to brand plans

He & She MD

Platinum injectable, intro (6-mo)Compounded
$139/mo
semaglutide
Platinum oral, intro (6-mo)Compounded
$199/mo
semaglutide
Injectable, 12-month prepayCompounded
$99/mo
semaglutide

⛔ THIS ROW PREVIOUSLY DESCRIBED A "microdose" TIER THAT DOES NOT EXIST. Read live from heandshemd.com/weight-loss on 2026-08-14: the word "microdose" appears NOWHERE on the homepage or the weight-loss page. $99 is Semaglutide Injection, and its own asterisk reads "Price for purchase of 12 months supply" — a twelve-month prepay divided down, which is the LONGEST commitment the clinic sells, not the shortest. The figure was real; the product was invented. The standing month-to-month rate for injectable semaglutide is $199.

StartingCompounded
$199/mo
tirzepatide

Injectable tirzepatide intro $199/mo (regular $289/mo)

What’s included

PreventiveMD

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

Not stated

Lab work

Not stated

Coaching

Not stated

He & She MD

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

In the price

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

PreventiveMD

7.4/10

Overall

He & She MD

9.3/10

Value25%

5.0A
vs
B
9.7

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.5A
vs
B
8.5

Accessibility10%

7.8A
vs
B
10.0

Support10%

5.5A
vs
B
8.5

Features & Coverage

FeaturePreventiveMDHe & She MD
Starting Price$83/mo$99/mo
Features8 features8 features
States Available3650
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About PreventiveMD

All-in figures start at $83/mo for compounded semaglutide and $97/mo for compounded tirzepatide. Foundayo, Zepbound and Wegovy come as brands under a membership arrangement. Requests reach a US-licensed provider inside 24 hours, and once approved the drug is sent to your door with care continuing through a portal online. Peptide therapy shares the platform with the GLP-1 side, all physician-guided.

Read our full PreventiveMD review →

About He & She MD

GLP-1 Platinum opens at $139/month as an introductory rate on injectables, then settles at $199. That buys expedited delivery at no cost, board-certified clinicians reachable without limit, GLP-1 coaching and progress tracking inside the app, and billing only happens if a prescription is actually written. He & She MD works nationwide with doctor-prescribed compounded semaglutide and tirzepatide, injectable or oral, a microdose option, and access under brand names to Wegovy, Ozempic and Zepbound. Every state receives shipments except Louisiana. Certification is LegitScript.

Read our full He & She MD review →

Pros & Cons

PreventiveMD

What we like

  • Semaglutide at $149 a month, 89% below the $1299 median for the same drug and form across this register
  • Tirzepatide at $299 a month, 76% below the $1249 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly figure covers medication and consult
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • Coverage is published for 36 states only, so this may not reach you
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

He & She MD

What we like

  • Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly figure covers medication, consult, shipping, coaching
  • Coverage is published for all 50 states
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: He & She MD

He & She MD takes it, 9.3 against 7.4, and it is especially strong on starting below a standard dose, with microdose tiers. PreventiveMD is no weak second and may fit you better on oral orforglipron alongside the injectables.

Choose PreventiveMD if…

You want oral orforglipron alongside the injectables and an opening price near $83 a month.

Choose He & She MD if…

You want starting below a standard dose, with microdose tiers and an opening price near $99 a month.

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8.8

Found

Tirzepatide at $169/month, 37% under the register median

8.3

Telos Rx

Starting below a standard dose, with microdose tiers

7.0

MyDrHank

An oral route if you will not self-inject

PreventiveMD vs He & She MD: FAQ

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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.