Piper vs Wisp
Wisp costs $36 less a month, and both sell semaglutide and tirzepatide.
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Piper
Best for: coverage in all 50 states, which most sellers will not confirm
Visit Piper →
If you are choosing between Piper and Wisp, the first difference is cost: Wisp is $36 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Piper leads our six-part score, 7.4 to 6.5.
Piper vs Wisp price
Wisp is the cheaper way in: $99 a month against $135 a month at Piper. That is $36 less each month (27% lower), or about $432 over a year of treatment.
Drug by drug: Semaglutide is cheaper at Piper ($135 a month vs $225 a month); tirzepatide is cheaper at Wisp ($99 a month vs $199 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format, Piper prices compounded injections, while Wisp prices compounded injections and brand-name pens.
If you want the FDA-approved brand rather than a compounded version, Wisp is the only one of the two with a brand-name price.
Where each one treats patients
Piper lists 50 states, and Wisp does not publish where it ships.
Pricing
Piper
Wisp
Monthly subscription supplement, NOT a prescription GLP-1 medication. 'subscription' in form keeps it out of the GLP-1 hero price. drug omitted intentionally.
Zepbound $99/mo (compounded sublingual semaglutide $225/mo)
What each price covers
Both prices cover the medication itself and shipping.
Piper's price also covers the clinician visit, which Wisp does not claim.
Piper is silent on lab work and coaching.
Wisp is silent on the clinician visit, lab work and coaching.
Piper
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Wisp
Covered by the monthly price
Medication
In the price
Clinician visits
Not stated
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, Piper scores 7.4 and Wisp 6.5 out of 10.
Piper is stronger on trust & safety (8.5 vs 6.5), accessibility (10.0 vs 5.0) and support (7.0 vs 4.5).
Wisp is stronger on value (3.5 vs 3.0).
Effectiveness and user experience are within half a point.
Piper
7.4/10
Wisp
6.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
Neither Piper nor Wisp has an FDA warning letter on record with us.
Features & Coverage
| Feature | Piper | Wisp |
|---|---|---|
| Starting Price | $135/mo | ✓$99/mo |
| Features | 3 features | ✓8 features |
| States Available | 50 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | None | None |
About Piper
Piper is a telehealth weight loss seller offering compounded GLP-1 medications at competitive prices.
Read our full Piper review →About Wisp
$225/month buys a compounded sublingual semaglutide drops formulation from Wisp. Its weight care vertical also stocks three brand names: Saxenda, Zepbound, and Wegovy. A board-certified provider completes the review inside 24-72 hours. LegitScript certification is in place.
Read our full Wisp review →Pros & Cons
Piper
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits and shipping
- Serves all 50 states
- We found no FDA warning letters issued to Piper
Watch-outs
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Wisp
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication and shipping
- We found no FDA warning letters issued to Wisp
Watch-outs
- Semaglutide costs $225 a month, 22% above the $184 median for compounded semaglutide across the sellers we compare
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Piper wins this one, 7.4 to 6.5, above all for coverage in all 50 states, which most sellers will not confirm. Wisp undercuts it by $36 a month, so if the monthly bill is what decides it, Wisp is the pick. Wisp fits better if an oral route if you will not self-inject is your priority.
Choose Piper if…
You want coverage in all 50 states, which most sellers will not confirm and an opening price near $135 a month.
Choose Wisp if…
You want an oral route if you will not self-inject and an opening price near $99 a month.
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Sesame Care
Oral orforglipron alongside the injectables
From $59/mo
Get started →Collective
Flat any-dose pricing, if you can absorb a $199 annual membership on top
From $59/mo
Get started →Found
Tirzepatide at $169/month, 37% below the typical price
From $149/mo
Get started →Piper vs Wisp: FAQ
Close alternatives to Piper and Wisp
- Piper vs Livv
- Piper vs Somi Health
- Piper vs Idgie Health
- Piper vs HealthRX
- Wisp vs GobyMeds
- Wisp vs HeliMeds
Or see the full category ranking.
Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.