HealthRX vs Piper
HealthRX costs $2 less a month, and both sell semaglutide and tirzepatide.
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Piper
Best for: coverage in all 50 states, which most sellers will not confirm
Visit Piper →If you are choosing between HealthRX and Piper, the first difference is cost: HealthRX is $2 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. HealthRX leads our six-part score, 7.7 to 7.4.
HealthRX vs Piper price
HealthRX is the cheaper way in: $133 a month against $135 a month at Piper. That is $2 less each month (1% lower), or about $24 over a year of treatment.
Drug by drug: Semaglutide is cheaper at HealthRX ($133 a month vs $135 a month); tirzepatide is cheaper at Piper ($199 a month vs $209 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format they match: each offers compounded injections.
Where each one treats patients
HealthRX does not publish where it ships, and Piper lists 50 states.
Pricing
HealthRX
Flat rate, same price at every dose; 3-month plan from $133/mo, 12-month plan from $99/mo
Flat rate, same price at every dose; 3-month plan from $209/mo, 12-month plan from $179/mo
Piper
What each price covers
Both prices cover the clinician visit, the medication itself and shipping.
HealthRX is silent on lab work and coaching.
Piper is silent on lab work and coaching.
HealthRX
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Piper
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, HealthRX scores 7.7 and Piper 7.4 out of 10.
HealthRX is stronger on value (7.3 vs 3.0).
Piper is stronger on trust & safety (8.5 vs 6.5) and accessibility (10.0 vs 5.0).
Effectiveness, user experience and support are within half a point.
HealthRX
7.7/10
Piper
7.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
Neither HealthRX nor Piper has an FDA warning letter on record with us.
Features & Coverage
| Feature | HealthRX | Piper |
|---|---|---|
| Starting Price | ✓$133/mo | $135/mo |
| Features | ✓6 features | 3 features |
| States Available | Not disclosed | 50 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warning Letters | None | None |
About HealthRX
Three things are missing from the site: the name of the pharmacy doing the compounding, the roster of states where prescriptions are written, and any medical director. What is there is a LegitScript certificate, number 50087439, and the FDA's compounded-drug disclaimer. Prices hold steady whatever your dose, insurance plays no part, and overnight cold shipping costs nothing extra. A clinician licensed in the US turns around the brief online assessment inside 24 hours; if the answer is yes, a 503A compounder holding a license sends the semaglutide or tirzepatide within 24-48 hours.
Read our full HealthRX review →About Piper
Piper is a telehealth weight loss seller offering compounded GLP-1 medications at competitive prices.
Read our full Piper review →Pros & Cons
HealthRX
What we like
- Semaglutide costs $133 a month, 28% below the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $209 a month, 16% below the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to HealthRX
Watch-outs
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Piper
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits and shipping
- Serves all 50 states
- We found no FDA warning letters issued to Piper
Watch-outs
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
HealthRX wins this one, 7.7 to 7.4, above all for compounded semaglutide at $133/month. It also costs $2 less each month than Piper. Piper fits better if coverage in all 50 states, which most sellers will not confirm is your priority.
Choose HealthRX if…
You want compounded semaglutide at $133/month and an opening price near $133 a month.
Choose Piper if…
You want coverage in all 50 states, which most sellers will not confirm and an opening price near $135 a month.
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He & She MD
Starting below a standard dose, with microdose tiers
From $99/mo
Get started →Wellorithm
Compounded semaglutide at $247/month
From $247/mo
Get started →Willow
Seeing what it charges before you answer any medical questions
From $299/mo
Get started →HealthRX vs Piper: FAQ
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