Open Water Rx vs SkinnyRx
SkinnyRx costs $19.75 less a month, and both sell semaglutide and tirzepatide.
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
Open Water Rx
Best for: a flat, all-inclusive semaglutide or tirzepatide price that does not rise with the dose
Visit Open Water Rx →
If you are choosing between Open Water Rx and SkinnyRx, the first difference is cost: SkinnyRx is $19.75 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Open Water Rx leads our six-part score, 7.9 to 5.9. One of the two has an FDA warning letter on record, covered below.
Open Water Rx vs SkinnyRx price
SkinnyRx is the cheaper way in: $149.25 a month against $169 a month at Open Water Rx. That is $19.75 less each month (12% lower), or about $237 over a year of treatment.
Drug by drug: Semaglutide is cheaper at SkinnyRx ($149.25 a month vs $169 a month); tirzepatide is cheaper at Open Water Rx ($219 a month vs $224.25 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format they match: each offers compounded injections and an oral option.
Where each one treats patients
Open Water Rx lists 28 states, and SkinnyRx does not publish where it ships.
Pricing
Open Water Rx
One-month plan $169 total on /pricing (September 2026); $495 for 3 months, $960 for 6 months. All-inclusive of clinician review, medication if prescribed and shipping; the site states the price does not change with dose.
One-month plan $219 total on /pricing (September 2026); $645 for 3 months, $1,260 for 6 months.
Oral semaglutide tablets, one-month plan $199 total; $570 for 3 months, $1,000 for 6 months.
Oral tirzepatide tablets, one-month plan $319 total; $897 for 3 months, $1,650 for 6 months.
SkinnyRx
'As low as $149.25/mo*' — plan-length/promo dependent (matches the sitewide '25% lower prices' promo, $199 x 0.75); standard single-month rate not published pre-intake. Microdose available; free overnight shipping.
'As low as $199/mo*' on /products/semaglutide-oral; once-daily.
'As low as $249/mo*' on /products/semaglutide-tablets.
'As low as $224.25/mo*' and 'Starting at $224.25/mo with free overnight shipping'; microdose available; once-weekly.
'As low as $224.25/mo*' on /products/tirzepatide-tablets; once-daily.
'$1,400/mo*' — '*Price shown applies to Monthly plan paid upfront or with buy now, pay later programs.' 'No membership fees. Same price at every dose.'
'$1,400/mo*' on /products/wegovy-injectable. Wegovy PILL is listed 'Unavailable' ('available via SkinnyRx Membership', fee not published).
'$1,400/mo*' on /products/mounjaro.
'$1,400/mo*' on /products/zepbound. Foundayo (orforglipron) pill also listed but 'Unavailable' — price not published.
What each price covers
Both prices cover the clinician visit, the medication itself and shipping.
Open Water Rx is silent on lab work and coaching.
SkinnyRx is silent on lab work and coaching.
Open Water Rx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
SkinnyRx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, Open Water Rx scores 7.9 and SkinnyRx 5.9 out of 10.
Open Water Rx is stronger on user experience (8.0 vs 3.0), trust & safety (9.0 vs 1.0) and accessibility (6.5 vs 5.0).
SkinnyRx is stronger on value (6.5 vs 6.0).
Effectiveness and support are within half a point.
Open Water Rx
7.9/10
SkinnyRx
5.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent SkinnyRx a warning letter dated February 20, 2026 (letter 717989), and it is still open.
Open Water Rx has no FDA warning letter on record with us.
Features & Coverage
| Feature | Open Water Rx | SkinnyRx |
|---|---|---|
| Starting Price | $169/mo | ✓$149.25/mo |
| Features | ✓4 features | 3 features |
| States Available | 28 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | ✓None | 1 letter |
About Open Water Rx
Open Water Rx is a Tampa, Florida telehealth platform (Open Water Rx LLC, which also trades as Surfbound and Surfbound Health) for GLP-1 weight loss, longevity and men's health. Compounded semaglutide is $169 and tirzepatide $219 for a one-month plan, all-inclusive and the same at every dose, with three- and six-month plans and oral tablets also priced on its own site. Its pharmacy partners are Emerald (Tampa, FL), Striker (Katy, TX), Foothills (Tempe, AZ) and EPIQ Scripts (Texas), each listed with a state license.
Read our full Open Water Rx review →About SkinnyRx
SkinnyRx sells compounded semaglutide and tirzepatide as injectables, with a microdosing option, prescribed by licensed US clinicians. The consult and free overnight shipping are bundled into a single monthly cash price.
Read our full SkinnyRx review →Pros & Cons
Open Water Rx
What we like
- Semaglutide costs $169 a month, close to the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $219 a month, 12% below the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication, clinician visits and shipping
- Names 3 pharmacies that fill its prescriptions, which most sellers do not
- We found no FDA warning letters issued to Open Water Rx
- Offers both oral and injectable options, so the format is your choice
Watch-outs
- Serves only 28 states, so check that yours is one of them
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
SkinnyRx
What we like
- Semaglutide costs $149.25 a month, 19% below the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $224.25 a month, 10% below the $250 median for compounded tirzepatide across the sellers we compare
- The monthly price includes the medication, clinician visits and shipping
- Offers both oral and injectable options, so the format is your choice
Watch-outs
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued SkinnyRx a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
SkinnyRx is where we would start, above all for starting below a standard dose, with microdose tiers. It also costs $19.75 less each month than Open Water Rx. Open Water Rx fits better if a flat, all-inclusive semaglutide or tirzepatide price that does not rise with the dose is your priority.
Choose Open Water Rx if…
You want a flat, all-inclusive semaglutide or tirzepatide price that does not rise with the dose and an opening price near $169 a month.
Choose SkinnyRx if…
You want starting below a standard dose, with microdose tiers and an opening price near $149.25 a month.
Ready to start? GLP-1 providers we have vetted
Telehealth providers, vetted by us, prescribing GLP-1 online.
Vetted by our editors · no insurance required
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
Found
Tirzepatide at $169/month, 37% below the typical price
From $149/mo
Get started →Breeze Meds
Knowing which pharmacy fills the vial: it names Belmar Pharmacy
From $199/mo
Get started →HealthRX
Compounded semaglutide at $133/month
From $133/mo
Get started →Open Water Rx vs SkinnyRx: FAQ
Close alternatives to Open Water Rx and SkinnyRx
- Open Water Rx vs MyDrHank
- Open Water Rx vs Healthicare
- Open Water Rx vs YOURx Health
- SkinnyRx vs MedLeanRx
- SkinnyRx vs Rivo Health
- SkinnyRx vs YOURx Health
Or see the full category ranking.