MedLeanRx vs SkinnyRx
MedLeanRx and SkinnyRx both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.
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MedLeanRx
Best for: seeing what it charges before you answer any medical questions
Visit MedLeanRx →
If you are choosing between MedLeanRx and SkinnyRx, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. MedLeanRx leads our six-part score, 6.5 to 5.9. One of the two has an FDA warning letter on record, covered below.
MedLeanRx vs SkinnyRx price
MedLeanRx and SkinnyRx start at within a dollar of each other ($149 and $149.25 a month), so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.
Drug by drug: Semaglutide costs the same at both, $149 a month; tirzepatide is cheaper at SkinnyRx ($224.25 a month vs $269 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format they match: each offers compounded injections and an oral option.
Where each one treats patients
MedLeanRx lists 1 state, and SkinnyRx does not publish where it ships.
Pricing
MedLeanRx
Weekly semaglutide vial $149/mo; plans 'start at $149/month for the starting dose' — pricing may vary with medication and dosage
Needle-free daily oral semaglutide tablets, $149/mo
$269/mo standard; intro bundle: 2-month supply at 2 mg weekly for $325 (~$163/mo), Texas clients only, while supplies last
SkinnyRx
'As low as $149.25/mo*' — plan-length/promo dependent (matches the sitewide '25% lower prices' promo, $199 x 0.75); standard single-month rate not published pre-intake. Microdose available; free overnight shipping.
'As low as $199/mo*' on /products/semaglutide-oral; once-daily.
'As low as $249/mo*' on /products/semaglutide-tablets.
'As low as $224.25/mo*' and 'Starting at $224.25/mo with free overnight shipping'; microdose available; once-weekly.
'As low as $224.25/mo*' on /products/tirzepatide-tablets; once-daily.
'$1,400/mo*' — '*Price shown applies to Monthly plan paid upfront or with buy now, pay later programs.' 'No membership fees. Same price at every dose.'
'$1,400/mo*' on /products/wegovy-injectable. Wegovy PILL is listed 'Unavailable' ('available via SkinnyRx Membership', fee not published).
'$1,400/mo*' on /products/mounjaro.
'$1,400/mo*' on /products/zepbound. Foundayo (orforglipron) pill also listed but 'Unavailable' — price not published.
What each price covers
Both prices cover the clinician visit, the medication itself and shipping.
MedLeanRx is silent on lab work and coaching.
SkinnyRx is silent on lab work and coaching.
MedLeanRx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
SkinnyRx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, MedLeanRx scores 6.5 and SkinnyRx 5.9 out of 10.
MedLeanRx is stronger on user experience (8.0 vs 3.0) and trust & safety (7.5 vs 1.0).
SkinnyRx is stronger on value (6.5 vs 3.0) and accessibility (5.0 vs 2.2).
Effectiveness and support are within half a point.
MedLeanRx
6.5/10
SkinnyRx
5.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent SkinnyRx a warning letter dated February 20, 2026 (letter 717989), and it is still open.
MedLeanRx has no FDA warning letter on record with us.
Features & Coverage
| Feature | MedLeanRx | SkinnyRx |
|---|---|---|
| Starting Price | ✓$149/mo | $149.25/mo |
| Features | ✓8 features | 3 features |
| States Available | 1 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | ✓None | 1 letter |
About MedLeanRx
Texas and nowhere else. MedLeanRx works out of Spring, TX with physicians guiding care, charging $149/month for compounded semaglutide, taken as a weekly shot or a daily oral tablet, and $269/month for compounded tirzepatide. A brand route also exists at a $99/month fee covering Wegovy, Zepbound and Foundayo (orforglipron), with the drug itself billed on its own. Fill in a 5-minute assessment, wait 24-48 hours for a physician to read it, then delivery follows free on plans you can cancel whenever.
Read our full MedLeanRx review →About SkinnyRx
SkinnyRx sells compounded semaglutide and tirzepatide as injectables, with a microdosing option, prescribed by licensed US clinicians. The consult and free overnight shipping are bundled into a single monthly cash price.
Read our full SkinnyRx review →Pros & Cons
MedLeanRx
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to MedLeanRx
Watch-outs
- Serves only 1 states, so check that yours is one of them
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
SkinnyRx
What we like
- Semaglutide costs $149.25 a month, 19% below the $184 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $224.25 a month, 10% below the $250 median for compounded tirzepatide across the sellers we compare
- The monthly price includes the medication, clinician visits and shipping
- Offers both oral and injectable options, so the format is your choice
Watch-outs
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- The FDA has issued SkinnyRx a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
SkinnyRx is where we would start, above all for starting below a standard dose, with microdose tiers. MedLeanRx fits better if seeing what it charges before you answer any medical questions is your priority.
Choose MedLeanRx if…
You want seeing what it charges before you answer any medical questions and an opening price near $149 a month.
Choose SkinnyRx if…
You want starting below a standard dose, with microdose tiers and an opening price near $149.25 a month.
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Willow
Seeing what it charges before you answer any medical questions
From $299/mo
Get started →Sesame Care
Oral orforglipron alongside the injectables
From $59/mo
Get started →Collective
Flat any-dose pricing, if you can absorb a $199 annual membership on top
From $59/mo
Get started →MedLeanRx vs SkinnyRx: FAQ
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