Onyx Weight Loss vs CoreAge Rx
An in-depth comparison of two leading GLP-1 Providers
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Onyx Weight Loss
Best for: starting below a standard dose, with microdose tiers
Visit Onyx Weight Loss →
CoreAge Rx
Best for: semaglutide at $99/month, 48% under the register median
Visit CoreAge Rx →Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, both start around $99/mo, and CoreAge Rx finishes ahead, 9.1 to 8.3. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
Onyx Weight Loss
Verbatim: 'Starting at $228/month' (GLP-1 Agonist plan). Includes medication and supplies shipped to home. Entry tier only; higher-dose pricing not disclosed.
Verbatim: 'Starting at $280/month' (GLP-1/GIP Agonist plan). Includes medication and supplies. Entry tier only; specific drug name inferred from GLP-1/GIP dual agonist designation.
Verbatim: '$99/MONTH' (GLP-1 Microdosing plan). Low-dose gradual-start option.
CoreAge Rx
Re-verified 2026-08-05: homepage + Preventive Longevity section both show "Semaglutide — Starting at $99/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.
Re-verified 2026-08-05: homepage GLP-1 hero + Preventive Longevity section both show "Tirzepatide — Starting at $149/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.
What’s included
Onyx Weight Loss
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
CoreAge Rx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Onyx Weight Loss
8.3/10
CoreAge Rx
9.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Onyx Weight Loss | CoreAge Rx |
|---|---|---|
| Starting Price | $99/mo | $99/mo |
| Features | ✓8 features | 6 features |
| States Available | 8 | ✓50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Onyx Weight Loss
GLP-1 (semaglutide-type) plans begin at $228/month; GLP-1/GIP (tirzepatide-type) plans at $280/month. There is also a $99/month GLP-1 microdosing option for anyone wanting a gradual-titration start. Onyx Weight Loss runs a nurse-practitioner-led telehealth clinic out of Mooresville, NC, set up by Madalyn Vangile RN and Tasha Vangile FNP-C, and it covers 8 states with HRT and peptides sold beside the GLP-1s. Its partner Strive Pharmacy ships medication and supplies home.
Read our full Onyx Weight Loss review →About CoreAge Rx
Shipping is free, 2-day, and reaches all 50 states. CoreAge Rx sells LegitScript-verified compounded semaglutide plus tirzepatide, with licensed physicians behind it and 24/7 support. Its own claim: nobody in the compounded GLP-1 space prices more competitively.
Read our full CoreAge Rx review →Pros & Cons
Onyx Weight Loss
What we like
- Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly figure covers medication, consult, shipping
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- Coverage is published for 8 states only, so this may not reach you
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
CoreAge Rx
What we like
- Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
- Tirzepatide at $149 a month, 44% below the $267 median for the same drug and form across this register
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
- The monthly figure covers medication, consult, shipping
- Coverage is published for all 50 states
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
CoreAge Rx takes it, 9.1 against 8.3, and it is especially strong on semaglutide at $99/month, 48% under the register median. Onyx Weight Loss is no weak second and may fit you better on starting below a standard dose, with microdose tiers.
Choose Onyx Weight Loss if…
You want starting below a standard dose, with microdose tiers and an opening price near $99 a month.
Choose CoreAge Rx if…
You want semaglutide at $99/month, 48% under the register median and an opening price near $99 a month.
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Trimi Health
Knowing which pharmacy fills the vial — it names VialsRx
From $99/mo
Get started →Strut Health
Semaglutide at $99/month, 48% under the register median
From $99/mo
Get started →Oak
Semaglutide at $119/month, 37% under the register median
From $119/mo
Get started →Onyx Weight Loss vs CoreAge Rx: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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