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NP2GO vs Roen Rx

NP2GO costs $1 less a month, and both sell semaglutide and tirzepatide.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
NP2GO logo

NP2GO

6.7
★★★☆☆3.4/5

Best for: compounded semaglutide at $150/month

Visit NP2GO →
VS
Roen Rx logo

Roen Rx

6.9
★★★★☆3.5/5

Best for: compounded semaglutide at $151/month

Visit Roen Rx →

If you are choosing between NP2GO and Roen Rx, the first difference is cost: NP2GO is $1 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Roen Rx leads our six-part score, 6.9 to 6.7. One of the two has an FDA warning letter on record, covered below.

NP2GO vs Roen Rx price

NP2GO is the cheaper way in: $150 a month against $151 a month at Roen Rx. That is $1 less each month (1% lower), or about $12 over a year of treatment.

Drug by drug: Semaglutide is cheaper at NP2GO ($150 a month vs $151 a month); tirzepatide is cheaper at Roen Rx ($216 a month vs $250 a month).

Medications and formats

Both sell semaglutide and tirzepatide.

On format they match: each offers compounded injections.

Where each one treats patients

NP2GO lists 40 states, and Roen Rx does not publish where it ships.

Pricing

NP2GO

0.25mg (Pay As You Go)Compounded
$150/mo
semaglutide
0.50mg (Pay As You Go)Compounded
$175/mo
semaglutide
1mg (Pay As You Go)Compounded
$235/mo
semaglutide
1.7mg (Pay As You Go)Compounded
$250/mo
semaglutide
2.5mg (Pay As You Go)Compounded
$350/mo
semaglutide
0.25-1mg (Month-to-Month Membership)Compounded
$199/mo
semaglutide
1.7-2.5mg (Month-to-Month Membership)Compounded
$299/mo
semaglutide
2.5mg (Pay As You Go)Compounded
$250/mo
tirzepatide
5mg (Pay As You Go)Compounded
$300/mo
tirzepatide
7.5mg (Pay As You Go)Compounded
$375/mo
tirzepatide
10mg (Pay As You Go)Compounded
$475/mo
tirzepatide
12.5mg (Pay As You Go)Compounded
$550/mo
tirzepatide
15mg (Pay As You Go)Compounded
$600/mo
tirzepatide
2.5-7.5mg (Month-to-Month Membership)Compounded
$299/mo
tirzepatide
10-15mg (Month-to-Month Membership)Compounded
$399/mo
tirzepatide

Roen Rx

Compounded Semaglutide (3-month supply, medication only)Compounded
$151/mo
semaglutide

Medication price only; a separate Roen Rx membership is required on top.

Compounded Tirzepatide (medication only)Compounded
$216/mo
tirzepatide

Medication price only; membership billed separately.

Brand GLP-1 with insurance (copay)Brand-name
$25/mo
semaglutide

As low as $25 monthly copay with insurance coordination; membership still required.

Required Roen Rx membership (subscription, medication NOT included)membership subscription
$39/mo

First month discounted to $39; standard recurring membership rate not published. GLP-1 medications are not included in the membership fee. drug omitted intentionally.

Semaglutide Bundle (membership + GLP-1, after first month)Compounded
$297/mo
semaglutide

All-in bundle: $217 first month, then $297/mo. 'bundle' in dose keeps it out of the molecule cost-engine so it does not double-count the standalone $151 med row.

Tirzepatide Bundle (membership + GLP-1, after first month)Compounded
$449/mo
tirzepatide

All-in bundle: $349 first month, then $449/mo.

What each price covers

Neither NP2GO nor Roen Rx spells out what its price covers, so ask whether the visit, the drug and shipping are all in the monthly figure.

Where each one scores higher

Overall, Roen Rx scores 6.9 and NP2GO 6.7 out of 10.

NP2GO is stronger on trust & safety (6.0 vs 3.5) and accessibility (8.4 vs 5.0).

Roen Rx is stronger on user experience (8.0 vs 2.5).

Value, effectiveness and support are within half a point.

How we score

NP2GO

6.7/10

Overall

Roen Rx

6.9/10

Value25%

6.5A
vs
B
6.5

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

2.5A
vs
B
8.0

Trust & Safety15%

6.0A
vs
B
3.5

Accessibility10%

8.4A
vs
B
5.0

Support10%

5.0A
vs
B
5.0

FDA warning letters

The FDA sent Roen Rx a warning letter dated June 8, 2026 (letter 728293), and it is still open.

NP2GO has no FDA warning letter on record with us.

Features & Coverage

FeatureNP2GORoen Rx
Starting Price✓$150/mo$151/mo
Features8 features8 features
States Available40Not disclosed
Compounded✓ Yes✓ Yes
Brand Name—✓ Yes
FSA/HSA Accepted——
FDA Warning Letters✓None1 letter

About NP2GO

The full pricing matrix for compounded semaglutide and compounded tirzepatide is published openly, split two ways: Pay As You Go, billed per dose, where a visit fee of $99 falls every 3 months; or a flat membership month to month. Semaglutide enters at $150/mo. Nurse practitioners lead the operation, which runs a clinic in Edmond, Oklahoma alongside telehealth, dates to 2019, and belongs to the Obesity Medicine Association. Weight-loss visits by video cover 39 states and DC.

Read our full NP2GO review →

About Roen Rx

Roen Rx sells compounded semaglutide as well as brand-name Ozempic, Wegovy, Zepbound, and Mounjaro, and it coordinates insurance. LegitScript approved. Insurance-covered brand GLP-1s run as low as $25/mo, and compounded semaglutide starts at $151/mo on a quarterly plan.

Read our full Roen Rx review →

Pros & Cons

NP2GO

What we like

  • Semaglutide costs $150 a month, 19% below the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $250 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
  • Serves 40 states
  • We found no FDA warning letters issued to NP2GO
  • A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake

Watch-outs

  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Roen Rx

What we like

  • Semaglutide costs $151 a month, 18% below the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $216 a month, 14% below the $250 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information

Watch-outs

  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • The FDA has issued Roen Rx a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Roen Rx

Roen Rx wins this one, 6.9 to 6.7, above all for compounded semaglutide at $151/month. NP2GO undercuts it by $1 a month, so if the monthly bill is what decides it, NP2GO is the pick. NP2GO fits better if compounded semaglutide at $150/month is your priority.

Choose NP2GO if…

You want compounded semaglutide at $150/month and an opening price near $150 a month.

Choose Roen Rx if…

You want compounded semaglutide at $151/month and an opening price near $151 a month.

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NP2GO vs Roen Rx: FAQ

NP2GO. It starts at $150 a month; Roen Rx starts at $151 a month, $1 more per month.
Yes, both sell semaglutide and tirzepatide.
NP2GO lists 40 states; Roen Rx does not publish where it ships. Confirm your state before paying.
Neither says. Ask NP2GO and Roen Rx for an itemized monthly total.
NP2GO has none. Roen Rx has an open FDA warning letter from June 8, 2026.
No. Neither NP2GO nor Roen Rx pays us anything.

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