MEDVi vs PlushCare
PlushCare costs $100 less a month, and both sell semaglutide.
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PlushCare
Best for: coverage in all 50 states, which most sellers will not confirm
Visit PlushCare →If you are choosing between MEDVi and PlushCare, the first difference is cost: PlushCare is $100 a month cheaper at the entry price. Both prescribe semaglutide, so moving from one to the other would not change your drug. MEDVi leads our six-part score, 7.1 to 6.4. One of the two has an FDA warning letter on record, covered below.
MEDVi vs PlushCare price
PlushCare is the cheaper way in: $149 a month against $249 a month at MEDVi. That is $100 less each month (40% lower), or about $1,200 over a year of treatment.
Drug by drug: Semaglutide is cheaper at PlushCare ($149 a month vs $249 a month).
Medications and formats
Both sell semaglutide; only PlushCare lists tirzepatide.
On format they match: each offers compounded injections.
Where each one treats patients
MEDVi lists 48 states, and PlushCare lists 50 states.
They overlap in 48 states. PlushCare alone covers Mississippi and North Dakota.
Pricing
MEDVi
Refills are locked in at $299. The first month is $179 in the 'SUMMER Sale,' and some MEDVi landing pages offer the first month at $149.
Flat 'Starting at $249' — no intro discount shown.
$99 Membership + Medication Cost — medication cost not published (varies/insurance may reimburse). 'Availability is subject to change.'
$99 Membership + Medication Cost — medication cost not published. COMPOUNDED tirzepatide ($349 in our current entry) is no longer published anywhere on glp1.medvi.org, home.medvi.org, or the intake flow (0 mentions) — treat as discontinued/not published, do not carry the $349 row forward.
PlushCare
Range up to $299/mo
Range up to $599/mo
What each price covers
MEDVi's price also covers the clinician visit, the medication itself, shipping and coaching, which PlushCare does not claim.
MEDVi is silent on lab work.
PlushCare is silent on shipping and coaching.
That matters most for the drug: unless PlushCare confirms otherwise, budget for medication on top of its listed price.
MEDVi
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
PlushCare
Covered by the monthly price
Medication
Charged on top
Clinician visits
Charged on top
Shipping
Not stated
Lab work
Charged on top
Coaching
Not stated
Where each one scores higher
Overall, MEDVi scores 7.1 and PlushCare 6.4 out of 10.
MEDVi is stronger on user experience (8.0 vs 7.0) and support (8.5 vs 0.0).
PlushCare is stronger on trust & safety (7.5 vs 6.0).
Value, effectiveness and accessibility are within half a point.
MEDVi
7.1/10
PlushCare
6.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
The FDA sent MEDVi a warning letter dated February 20, 2026 (letter 721455), and it is still open.
PlushCare has no FDA warning letter on record with us.
Features & Coverage
| Feature | MEDVi | PlushCare |
|---|---|---|
| Starting Price | $249/mo | ✓$149/mo |
| Features | 7 features | ✓8 features |
| States Available | 48 | ✓50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | 1 letter | ✓None |
About MEDVi
Two clinical groups do the treating at MEDVi: CareGLP Affiliated P.C.s, plus clinicians from OpenLoop Health. Its weight-loss menu holds compounded GLP-1s, injections and tablets alike, the molecule being semaglutide, next to Zepbound and Wegovy under their brand names. Licensed US pharmacies fill all of it.
Read our full MEDVi review →About PlushCare
PlushCare is an established virtual primary-care telehealth platform and a subsidiary of Transcarent, Inc., a Delaware corporation that also owns Accolade, 2nd.MD, and 98point6 by Transcarent. Virtual visits with US board-certified physicians cost $30 per appointment insured and $129 self-pay. GLP-1 prescribing is a clinician-discretionary option within the broader primary-care relationship.
Read our full PlushCare review →Pros & Cons
MEDVi
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits, shipping and coaching
- Serves 48 states
- Names 3 pharmacies that fill its prescriptions, which most sellers do not
Watch-outs
- Semaglutide costs $249 a month, 35% above the $184 median for compounded semaglutide across the sellers we compare
- The FDA has issued MEDVi a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
- Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
PlushCare
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- Serves all 50 states
- We found no FDA warning letters issued to PlushCare
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
- Baseline bloodwork is required before a prescription
Watch-outs
- Not included in the monthly price: medication, clinician visits, lab work
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
MEDVi wins this one, 7.1 to 6.4, above all for knowing which pharmacy fills the vial: it names Triad Rx. PlushCare undercuts it by $100 a month, so if the monthly bill is what decides it, PlushCare is the pick. PlushCare fits better if coverage in all 50 states, which most sellers will not confirm is your priority.
Choose MEDVi if…
You want knowing which pharmacy fills the vial: it names Triad Rx and an opening price near $249 a month.
Choose PlushCare if…
You want coverage in all 50 states, which most sellers will not confirm and an opening price near $149 a month.
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Sesame Care
Oral orforglipron alongside the injectables
From $59/mo
Get started →Collective
Flat any-dose pricing, if you can absorb a $199 annual membership on top
From $59/mo
Get started →Found
Tirzepatide at $169/month, 37% below the typical price
From $149/mo
Get started →MEDVi vs PlushCare: FAQ
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