Lean Meds vs PlexusDx
An in-depth comparison of two leading GLP-1 Providers
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Lean Meds
Best for: knowing which pharmacy fills the vial — it names Belmar Pharmacy
Visit Lean Meds →
Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, Lean Meds opens cheaper — $79/mo against $129, and Lean Meds finishes ahead, 9.3 to 8.3. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
Lean Meds
Standing month-to-month rate. The advertised $69 is the 12-month prepay tier; 3-month is $76 and 6-month is $73.
Standing month-to-month rate. Prepay tiers: $105 for 3 months, $100 for 6, $95 for 12.
PlexusDx
What’s included
Lean Meds
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
PlexusDx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
Not stated
Lab work
Not stated
Coaching
Not stated
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Lean Meds
9.3/10
PlexusDx
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Lean Meds | PlexusDx |
|---|---|---|
| Starting Price | ✓$79/mo | $129/mo |
| Features | 7 features | ✓8 features |
| States Available | 50 | 50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Lean Meds
Titrating up does not raise the rate, which is flat and monthly: $79 to start on compounded semaglutide, $109 on compounded tirzepatide, the telehealth visit and shipping absorbed into both. Clinicians come from the OpenLoop Health network. Trinity HealthCare Supply, LLC operates the service and puts names to its five dispensing pharmacies as well as to the physicians who prescribe.
Read our full Lean Meds review →About PlexusDx
PlexusDx (plexusdx.com) prices a microdose GLP-1 from $129/month, compounded semaglutide from $149/month and compounded tirzepatide from $249/month, and also sells a combination GLP-Squared protocol. An independent US-licensed clinician reviews each patient through a state-licensed telehealth platform, medications come from state-licensed pharmacies, and licensed providers cover all 50 states. What sets it apart is an optional Precision Peptide genetic test returning 151 insights, discounted to $99 after a first order.
Read our full PlexusDx review →Pros & Cons
Lean Meds
What we like
- Semaglutide at $79 a month, 58% below the $189 median for the same drug and form across this register
- Tirzepatide at $109 a month, 59% below the $267 median for the same drug and form across this register
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
- The monthly figure covers medication, consult, shipping
- Coverage is published for all 50 states
- Names 5 dispensing pharmacies, which most sellers in this register do not do
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
PlexusDx
What we like
- Semaglutide at $129 a month, 32% below the $189 median for the same drug and form across this register
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly figure covers medication and consult
- Coverage is published for all 50 states
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Lean Meds takes it, 9.3 against 8.3, and it is especially strong on knowing which pharmacy fills the vial — it names Belmar Pharmacy. PlexusDx is no weak second and may fit you better on starting below a standard dose, with microdose tiers.
Choose Lean Meds if…
You want knowing which pharmacy fills the vial — it names Belmar Pharmacy and an opening price near $79 a month.
Choose PlexusDx if…
You want starting below a standard dose, with microdose tiers and an opening price near $129 a month.
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MyDrHank
An oral route if you will not self-inject
From $25/mo
Get started →SkinnyRx
Starting below a standard dose, with microdose tiers
From $149.25/mo
Get started →Trimi Health
Knowing which pharmacy fills the vial — it names VialsRx
From $99/mo
Get started →Lean Meds vs PlexusDx: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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