HumeCare+ vs OnlyRx
HumeCare+ costs $50 less a month, and both sell semaglutide and tirzepatide.
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OnlyRx
Best for: seeing what it charges before you answer any medical questions
Visit OnlyRx →If you are choosing between HumeCare+ and OnlyRx, the first difference is cost: HumeCare+ is $50 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. OnlyRx leads our six-part score, 6.6 to 5.7.
HumeCare+ vs OnlyRx price
HumeCare+ is the cheaper way in: $199 a month against $249 a month at OnlyRx. That is $50 less each month (20% lower), or about $600 over a year of treatment.
Drug by drug: Semaglutide is cheaper at HumeCare+ ($199 a month vs $249 a month); tirzepatide is cheaper at OnlyRx ($249 a month vs $299 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format they match: each offers compounded injections and an oral option.
Where each one treats patients
Neither HumeCare+ nor OnlyRx publishes the states it serves, so enter your state at the very start of each sign-up.
Pricing
HumeCare+
Shown at checkout after the intake questionnaire: $199/mo charged, with $299 struck through and 'SAVE $100.' HumeCare+ does not say whether $299 is a regular rate anyone pays or only a reference price.
At checkout after intake: $299/mo charged, $399 struck through. Sold as a combination with vitamin B12 and glycine rather than tirzepatide alone.
At checkout after intake: $199/mo charged, $299 struck through.
OnlyRx
What each price covers
Both prices cover the clinician visit and the medication itself.
OnlyRx's price also covers shipping, which HumeCare+ does not claim.
HumeCare+ is silent on shipping, lab work and coaching.
OnlyRx is silent on lab work and coaching.
HumeCare+
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
Not stated
Lab work
Not stated
Coaching
Not stated
OnlyRx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, OnlyRx scores 6.6 and HumeCare+ 5.7 out of 10.
HumeCare+ is stronger on value (4.4 vs 3.0).
OnlyRx is stronger on user experience (8.0 vs 3.0), trust & safety (6.5 vs 4.0) and support (7.0 vs 5.5).
Effectiveness and accessibility are within half a point.
HumeCare+
5.7/10
OnlyRx
6.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
Neither HumeCare+ nor OnlyRx has an FDA warning letter on record with us.
Features & Coverage
| Feature | HumeCare+ | OnlyRx |
|---|---|---|
| Starting Price | ✓$199/mo | $249/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | ✓ Yes | — |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | None | None |
About HumeCare+
Plans open from $199/mo, billed month by month and cancellable whenever, and both the drug and the hardware sit inside that. HumeCare+ comes from Hume Health, the company that sells body-composition scales, and the logic follows: clinician-prescribed compounded GLP-1 semaglutide arrives with a Hume Pod, so the patient can watch whether the weight leaving is fat or muscle. Which states it serves is unpublished, and the marketing site identifies neither the prescribing medical group nor the pharmacy.
Read our full HumeCare+ review →About OnlyRx
A summer promotion puts compounded semaglutide injections at $179/mo to start. OnlyRx takes cash only and sells both molecules two ways, injected or as oral disintegrating tablets (ODT), so a needle can be avoided; branded GLP-1s are written where appropriate. Prescribers are named, as is a fulfillment network of four pharmacies. All 50 states are served, and Buy Now Pay Later is offered.
Read our full OnlyRx review →Pros & Cons
HumeCare+
What we like
- Semaglutide costs $199 a month, close to the $184 median for compounded semaglutide across the sellers we compare
- The monthly price includes the medication and clinician visits
- We found no FDA warning letters issued to HumeCare+
- Offers both oral and injectable options, so the format is your choice
Watch-outs
- Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
OnlyRx
What we like
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to OnlyRx
Watch-outs
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
HumeCare+ is where we would start, above all for an oral route if you will not self-inject. It also costs $50 less each month than OnlyRx. OnlyRx fits better if seeing what it charges before you answer any medical questions is your priority.
Choose HumeCare+ if…
You want an oral route if you will not self-inject and an opening price near $199 a month.
Choose OnlyRx if…
You want seeing what it charges before you answer any medical questions and an opening price near $249 a month.
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Found
Tirzepatide at $169/month, 37% below the typical price
From $149/mo
Get started →Breeze Meds
Knowing which pharmacy fills the vial: it names Belmar Pharmacy
From $199/mo
Get started →HealthRX
Compounded semaglutide at $133/month
From $133/mo
Get started →HumeCare+ vs OnlyRx: FAQ
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