Price and states served both move. Read them off the seller's own site before you enroll.How our reviews work →

Ascend Vitality vs HumeCare+

Ascend Vitality and HumeCare+ both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.

Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more

By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Ascend Vitality logo

Ascend Vitality

5.6
★★★☆☆2.8/5

Best for: an oral route if you will not self-inject

Visit Ascend Vitality →
VS
HumeCare+ logo

HumeCare+

5.7
★★★☆☆2.9/5

Best for: an oral route if you will not self-inject

Visit HumeCare+ →

If you are choosing between Ascend Vitality and HumeCare+, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. HumeCare+ leads our six-part score, 5.7 to 5.6.

Ascend Vitality vs HumeCare+ price

Ascend Vitality and HumeCare+ start at the same figure, $199 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.

Drug by drug: Semaglutide costs the same at both, $199 a month; tirzepatide costs the same at both, $299 a month.

Medications and formats

Both sell semaglutide and tirzepatide.

On format they match: each offers compounded injections and an oral option.

Where each one treats patients

Neither Ascend Vitality nor HumeCare+ publishes the states it serves, so enter your state at the very start of each sign-up.

Pricing

Ascend Vitality

Compounded Semaglutide (injectable)Compounded
$199/mo
semaglutide
Compounded Tirzepatide (injectable)Compounded
$299/mo
tirzepatide
Compounded Semaglutide Tablets (oral)Compounded · oral
$199/mo
semaglutide
Compounded Tirzepatide Tablets (oral)Compounded · oral
$299/mo
tirzepatide

HumeCare+

Compounded semaglutide injectionCompounded
$199/mo
semaglutide

Shown at checkout after the intake questionnaire: $199/mo charged, with $299 struck through and 'SAVE $100.' HumeCare+ does not say whether $299 is a regular rate anyone pays or only a reference price.

Compounded tirzepatide + vitamin B12 + glycineCompounded
$299/mo
tirzepatide

At checkout after intake: $299/mo charged, $399 struck through. Sold as a combination with vitamin B12 and glycine rather than tirzepatide alone.

Oral compounded semaglutideCompounded · oral
$199/mo
semaglutide

At checkout after intake: $199/mo charged, $299 struck through.

What each price covers

Both prices cover the medication itself.

HumeCare+'s price also covers the clinician visit, which Ascend Vitality does not claim.

Ascend Vitality is silent on the clinician visit, shipping, lab work and coaching.

HumeCare+ is silent on shipping, lab work and coaching.

Ascend Vitality

Covered by the monthly price

Medication

In the price

Clinician visits

Not stated

Shipping

Not stated

Lab work

Not stated

Coaching

Not stated

HumeCare+

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

Not stated

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall, HumeCare+ scores 5.7 and Ascend Vitality 5.6 out of 10.

HumeCare+ is stronger on support (5.5 vs 5.0).

Value, effectiveness, user experience, trust & safety and accessibility are within half a point.

How we score

Ascend Vitality

5.6/10

Overall

HumeCare+

5.7/10

Value25%

4.4A
vs
B
4.4

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

3.0A
vs
B
3.0

Trust & Safety15%

4.0A
vs
B
4.0

Accessibility10%

5.0A
vs
B
5.0

Support10%

5.0A
vs
B
5.5

FDA warning letters

Neither Ascend Vitality nor HumeCare+ has an FDA warning letter on record with us.

Features & Coverage

FeatureAscend VitalityHumeCare+
Starting Price$199/mo$199/mo
Features6 features✓8 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA Warning LettersNoneNone

About Ascend Vitality

Ascend Vitality starts compounded semaglutide at $199/mo and compounded tirzepatide at $299/mo, sold as both weekly injectables and needle-free daily tablets. The cash-pay seller is LegitScript-certified, with a discount on the 6-month plan and a cancel-anytime subscription model.

Read our full Ascend Vitality review →

About HumeCare+

Plans open from $199/mo, billed month by month and cancellable whenever, and both the drug and the hardware sit inside that. HumeCare+ comes from Hume Health, the company that sells body-composition scales, and the logic follows: clinician-prescribed compounded GLP-1 semaglutide arrives with a Hume Pod, so the patient can watch whether the weight leaving is fat or muscle. Which states it serves is unpublished, and the marketing site identifies neither the prescribing medical group nor the pharmacy.

Read our full HumeCare+ review →

Pros & Cons

Ascend Vitality

What we like

  • Semaglutide costs $199 a month, close to the $184 median for compounded semaglutide across the sellers we compare
  • The monthly price includes the medication
  • We found no FDA warning letters issued to Ascend Vitality
  • Offers both oral and injectable options, so the format is your choice

Watch-outs

  • Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

HumeCare+

What we like

  • Semaglutide costs $199 a month, close to the $184 median for compounded semaglutide across the sellers we compare
  • The monthly price includes the medication and clinician visits
  • We found no FDA warning letters issued to HumeCare+
  • Offers both oral and injectable options, so the format is your choice

Watch-outs

  • Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: HumeCare+

HumeCare+ wins this one, 5.7 to 5.6, above all for an oral route if you will not self-inject. Ascend Vitality fits better if an oral route if you will not self-inject is your priority.

Choose Ascend Vitality if…

You want an oral route if you will not self-inject and an opening price near $199 a month.

Choose HumeCare+ if…

You want an oral route if you will not self-inject and an opening price near $199 a month.

Ready to start? GLP-1 providers we have vetted

Telehealth providers, vetted by us, prescribing GLP-1 online.

Vetted by our editors · no insurance required

Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more

6.5

Sesame Care

Oral orforglipron alongside the injectables

8.4

Collective

Flat any-dose pricing, if you can absorb a $199 annual membership on top

8.6

Found

Tirzepatide at $169/month, 37% below the typical price

Ascend Vitality vs HumeCare+: FAQ

Neither on the entry price: Ascend Vitality and HumeCare+ both start at about $199 a month. The difference is in what the price includes.
Yes, both sell semaglutide and tirzepatide.
Ascend Vitality does not publish where it ships; HumeCare+ does not publish where it ships. Confirm your state before paying.
Both include the medication itself. Only HumeCare+ includes the clinician visit.
Ascend Vitality has none. HumeCare+ has none.
HumeCare+ pays us a commission on sign-ups through our links; Ascend Vitality does not. Scores are computed the same way for both.

Or see the full category ranking.