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HumeCare+ vs He & She MD

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
HumeCare+ logo

HumeCare+

5.7
★★☆☆2.9/5

Best for: an oral route if you will not self-inject

Visit HumeCare+
VS
He & She MD logo

He & She MD

9.3
★★★★4.7/5

Best for: starting below a standard dose, with microdose tiers

Visit He & She MD

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, He & She MD opens cheaper — $99/mo against $199, and He & She MD finishes ahead, 9.3 to 5.7. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

HumeCare+

Compounded semaglutide injectionCompounded
$199/mo
semaglutide

Read at the post-intake checkout (app.humecare.com/glp1/onboarding/checkout-v2) on 2026-08-14: $199/mo shown as the charged rate with $299 struck through and 'SAVE $100'. We could NOT establish whether the $299 is a standing rate this discounts or a reference anchor that is never charged, so $199 is recorded as the price and the $299 is described rather than used.

Compounded tirzepatide + vitamin B12 + glycineCompounded
$299/mo
tirzepatide

Post-intake checkout 2026-08-14: $299/mo charged, $399 struck through. Sold as a combination with vitamin B12 and glycine rather than tirzepatide alone.

Oral compounded semaglutideCompounded · oral
$199/mo
semaglutide

Post-intake checkout 2026-08-14: $199/mo charged, $299 struck through.

He & She MD

Platinum injectable, intro (6-mo)Compounded
$139/mo
semaglutide
Platinum oral, intro (6-mo)Compounded
$199/mo
semaglutide
Injectable, 12-month prepayCompounded
$99/mo
semaglutide

⛔ THIS ROW PREVIOUSLY DESCRIBED A "microdose" TIER THAT DOES NOT EXIST. Read live from heandshemd.com/weight-loss on 2026-08-14: the word "microdose" appears NOWHERE on the homepage or the weight-loss page. $99 is Semaglutide Injection, and its own asterisk reads "Price for purchase of 12 months supply" — a twelve-month prepay divided down, which is the LONGEST commitment the clinic sells, not the shortest. The figure was real; the product was invented. The standing month-to-month rate for injectable semaglutide is $199.

StartingCompounded
$199/mo
tirzepatide

Injectable tirzepatide intro $199/mo (regular $289/mo)

What’s included

HumeCare+

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

Not stated

Lab work

Not stated

Coaching

Not stated

He & She MD

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

In the price

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

HumeCare+

5.7/10

Overall

He & She MD

9.3/10

Value25%

4.6A
vs
B
9.7

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

3.0A
vs
B
8.0

Trust & Safety15%

4.0A
vs
B
8.5

Accessibility10%

5.0A
vs
B
10.0

Support10%

5.5A
vs
B
8.5

Features & Coverage

FeatureHumeCare+He & She MD
Starting Price$199/mo$99/mo
Features8 features8 features
States AvailableNot disclosed50
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About HumeCare+

Plans open from $199/mo, billed month by month and cancellable whenever, and both the drug and the hardware sit inside that. HumeCare+ comes from Hume Health, the company that sells body-composition scales, and the logic follows: clinician-prescribed compounded GLP-1 semaglutide arrives with a Hume Pod, so the patient can watch whether the weight leaving is fat or muscle. Which states it serves is unpublished, and the marketing site identifies neither the prescribing medical group nor the pharmacy.

Read our full HumeCare+ review →

About He & She MD

GLP-1 Platinum opens at $139/month as an introductory rate on injectables, then settles at $199. That buys expedited delivery at no cost, board-certified clinicians reachable without limit, GLP-1 coaching and progress tracking inside the app, and billing only happens if a prescription is actually written. He & She MD works nationwide with doctor-prescribed compounded semaglutide and tirzepatide, injectable or oral, a microdose option, and access under brand names to Wegovy, Ozempic and Zepbound. Every state receives shipments except Louisiana. Certification is LegitScript.

Read our full He & She MD review →

Pros & Cons

HumeCare+

What we like

  • Semaglutide at $199 a month, within the normal band around this register's $189 median for the same drug and form
  • The monthly figure covers medication and consult
  • No FDA warning letter matched this operator when we searched our enforcement register
  • Both oral and injectable options are on record, so the format is a choice rather than a condition

Watch-outs

  • No price appears until the medical intake is complete, so the cost cannot be compared before health information is submitted
  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

He & She MD

What we like

  • Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly figure covers medication, consult, shipping, coaching
  • Coverage is published for all 50 states
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: He & She MD

He & She MD takes it, 9.3 against 5.7, and it is especially strong on starting below a standard dose, with microdose tiers. HumeCare+ is no weak second and may fit you better on an oral route if you will not self-inject.

Choose HumeCare+ if…

You want an oral route if you will not self-inject and an opening price near $199 a month.

Choose He & She MD if…

You want starting below a standard dose, with microdose tiers and an opening price near $99 a month.

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9.4

Trimi Health

Knowing which pharmacy fills the vial — it names VialsRx

8.5

Strut Health

Semaglutide at $99/month, 48% under the register median

7.9

Oak

Semaglutide at $119/month, 37% under the register median

HumeCare+ vs He & She MD: FAQ

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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.