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Hone Health vs System Labs

Hone Health and System Labs sell different medications; this is what separates them.

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Hone Health logo

Hone Health

5.9
★★★☆☆3/5

Best for: compounded liraglutide at $160/month

Visit Hone Health →
VS
System Labs logo

System Labs

5.2
★★★☆☆2.6/5

Best for: seeing what it charges before you answer any medical questions

Visit System Labs →

If you are choosing between Hone Health and System Labs, price alone will not settle it. Hone Health leads our six-part score, 5.9 to 5.2.

Hone Health vs System Labs price

Hone Health publishes $60 a month. System Labs does not post a GLP-1 price we can quote, so you would only learn its cost after an intake.

Medications and formats

Hone Health lists liraglutide; System Labs does not name its drug.

On format, Hone Health prices compounded injections, while System Labs posts no priced format.

Where each one treats patients

Neither Hone Health nor System Labs publishes the states it serves, so enter your state at the very start of each sign-up.

Pricing

Hone Health

Compounded LiraglutideCompounded
$160/mo
liraglutide

Plus $25-$155/mo membership

NaltrexoneBrand-name
$60/mo
naltrexone

Plus $25-$155/mo membership

PhentermineBrand-name
$65/mo
phentermine

Plus $25-$155/mo membership

System Labs

Pricing not publicly listed.

What each price covers

Neither Hone Health nor System Labs spells out what its price covers, so ask whether the visit, the drug and shipping are all in the monthly figure.

Where each one scores higher

Overall, Hone Health scores 5.9 and System Labs 5.2 out of 10.

Hone Health is stronger on value (5.0 vs 3.0) and effectiveness (6.5 vs 5.0).

System Labs is stronger on user experience (8.0 vs 7.0).

Trust & safety, accessibility and support are within half a point.

How we score

Hone Health

5.9/10

Overall

System Labs

5.2/10

Value25%

5.0A
vs
B
3.0

Effectiveness25%

6.5A
vs
B
5.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
6.5

Accessibility10%

5.0A
vs
B
5.0

Support10%

5.0A
vs
B
5.0

FDA warning letters

Neither Hone Health nor System Labs has an FDA warning letter on record with us.

Features & Coverage

FeatureHone HealthSystem Labs
Starting Price$60/moNot published
Features✓5 features0 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes—
Brand Name✓ Yes—
FSA/HSA Accepted——
FDA Warning LettersNoneNone

About Hone Health

Hone Health is a comprehensive longevity telehealth platform for men and women, covering hormone optimization, weight management, sexual health, and metabolic health. Its weight loss formulary is compounded liraglutide at $160/mo, naltrexone at $60/mo, bupropion at $60/mo, phentermine at $65/mo, topiramate at $65/mo, and sermorelin at $130/mo. All of them require a membership, either $25/mo Basic or $149/mo Premium.

Read our full Hone Health review →

About System Labs

The catalog here is peptides and longevity: NAD+, glutathione, sermorelin and a lipotropic MIC+B12 injection, all filled by compounding pharmacies licensed in the US. Neither semaglutide nor tirzepatide appears on the public list. Of what is sold, MIC+B12 is the item adjacent to weight loss, at $89/month, while NAD+ and glutathione each run $149/month, and most carry intro pricing. System Laboratories, Inc. holds LegitScript verification and states HIPAA compliance.

Read our full System Labs review →

Pros & Cons

Hone Health

What we like

  • Liraglutide costs $160 a month
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • We found no FDA warning letters issued to Hone Health
  • A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
  • Baseline bloodwork is required before a prescription

Watch-outs

  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its liraglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality

System Labs

What we like

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • We found no FDA warning letters issued to System Labs

Watch-outs

  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license

Our Verdict

Winner: System Labs

System Labs is where we would start, above all for seeing what it charges before you answer any medical questions. Hone Health fits better if compounded liraglutide at $160/month is your priority.

Choose Hone Health if…

You want compounded liraglutide at $160/month and an opening price near $60 a month.

Choose System Labs if…

You want seeing what it charges before you answer any medical questions.

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7.3

RNK Health

An oral route if you will not self-inject

9.2

He & She MD

Starting below a standard dose, with microdose tiers

5.9

Wellorithm

Compounded semaglutide at $247/month

Hone Health vs System Labs: FAQ

Only Hone Health publishes a price ($60 a month). System Labs quotes after sign-up.
No. Hone Health lists liraglutide; System Labs lists no named drug.
Hone Health does not publish where it ships; System Labs does not publish where it ships. Confirm your state before paying.
Neither says. Ask Hone Health and System Labs for an itemized monthly total.
Hone Health has none. System Labs has none.
System Labs pays us a commission on sign-ups through our links; Hone Health does not. Scores are computed the same way for both.

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