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Hims vs Ryze Rx

Hims and Ryze Rx both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
Hims logo

Hims

6.8
★★★☆☆3.4/5

Best for: knowing which pharmacy fills the vial: it names Apostrophe Pharmacy LLC

Visit Hims →
VS
Ryze Rx logo

Ryze Rx

6.6
★★★☆☆3.3/5

Best for: seeing what it charges before you answer any medical questions

Visit Ryze Rx →

If you are choosing between Hims and Ryze Rx, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Hims leads our six-part score, 6.8 to 6.6. One of the two has an FDA warning letter on record, covered below.

Hims vs Ryze Rx price

Hims and Ryze Rx start at the same figure, $199 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.

Drug by drug: Semaglutide costs the same at both, $199 a month; tirzepatide is cheaper at Ryze Rx ($199 a month vs $299 a month).

Medications and formats

Both sell semaglutide and tirzepatide.

On format, Hims prices compounded injections and brand-name pens, while Ryze Rx prices compounded injections.

If you want the FDA-approved brand rather than a compounded version, Hims is the only one of the two with a brand-name price.

Where each one treats patients

Hims lists 50 states, and Ryze Rx does not publish where it ships.

Pricing

Hims

StartingCompounded
$199/mo
semaglutide
StartingBrand-name
$299/mo
tirzepatide

Brand Zepbound from $299/mo medication-only; requires Hims Weight Loss Membership ($149/mo)

Ryze Rx

StartingCompounded
$199/mo
semaglutide

Injectable semaglutide: $199 for 1 month or $499 for a 3-month bundle. The homepage headline of 'from $149/mo' does not match any listed plan.

StartingCompounded
$199/mo
tirzepatide

Injectable tirzepatide: $199 for 1 month or $799 for a 3-month bundle.

What each price covers

Both prices cover the medication itself.

Ryze Rx's price also covers the clinician visit and shipping, which Hims does not claim.

Hims is silent on shipping and lab work.

Ryze Rx is silent on lab work and coaching.

Hims

Covered by the monthly price

Medication

In the price

Clinician visits

Charged on top

Shipping

Not stated

Lab work

Not stated

Coaching

Charged on top

Ryze Rx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall, Hims scores 6.8 and Ryze Rx 6.6 out of 10.

Hims is stronger on trust & safety (7.0 vs 6.5) and accessibility (10.0 vs 5.0).

Ryze Rx is stronger on support (7.0 vs 3.0).

Value, effectiveness and user experience are within half a point.

How we score

Hims

6.8/10

Overall

Ryze Rx

6.6/10

Value25%

3.0A
vs
B
3.0

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.0A
vs
B
6.5

Accessibility10%

10.0A
vs
B
5.0

Support10%

3.0A
vs
B
7.0

FDA warning letters

The FDA sent Hims a warning letter dated September 9, 2025 (letter 716567), and it is still open.

Ryze Rx has no FDA warning letter on record with us.

Features & Coverage

FeatureHimsRyze Rx
Starting Price$199/mo$199/mo
Features2 features✓5 features
States Available50Not disclosed
Compounded✓ Yes✓ Yes
Brand Name✓ Yes—
FSA/HSA Accepted——
FDA Warning Letters1 letter✓None

About Hims

Hims is a major men's telehealth brand. Its weight loss offering is compounded semaglutide on a 6-month plan.

Read our full Hims review →

About Ryze Rx

Ryze Rx prices compounded injectable semaglutide and tirzepatide at $199/mo, or $499 and $799 for a 3-month bundle, with the physician consult and shipping included. Board-certified physicians prescribe and US-licensed compounding pharmacies ship. The platform also covers TRT and peptide therapy. Its homepage advertises care in all 50 states.

Read our full Ryze Rx review →

Pros & Cons

Hims

What we like

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication
  • Serves all 50 states
  • Names 4 pharmacies that fill its prescriptions, which most sellers do not

Watch-outs

  • Not included in the monthly price: clinician visits, coaching
  • The FDA has issued Hims a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
  • Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality

Ryze Rx

What we like

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication, clinician visits and shipping
  • We found no FDA warning letters issued to Ryze Rx

Watch-outs

  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Hims

Hims wins this one, 6.8 to 6.6, above all for knowing which pharmacy fills the vial: it names Apostrophe Pharmacy LLC. Ryze Rx fits better if seeing what it charges before you answer any medical questions is your priority.

Choose Hims if…

You want knowing which pharmacy fills the vial: it names Apostrophe Pharmacy LLC and an opening price near $199 a month.

Choose Ryze Rx if…

You want seeing what it charges before you answer any medical questions and an opening price near $199 a month.

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Hims vs Ryze Rx: FAQ

Neither on the entry price: Hims and Ryze Rx both start at about $199 a month. The difference is in what the price includes.
Yes, both sell semaglutide and tirzepatide.
Hims lists 50 states; Ryze Rx does not publish where it ships. Confirm your state before paying.
Both include the medication itself. Only Ryze Rx includes the clinician visit and shipping.
Hims has an open FDA warning letter from September 9, 2025. Ryze Rx has none.
No. Neither Hims nor Ryze Rx pays us anything.

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