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He & She MD vs MyStart Health

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
He & She MD logo

He & She MD

9.3
★★★★4.7/5

Best for: starting below a standard dose, with microdose tiers

Visit He & She MD
VS
MyStart Health logo

MyStart Health

6.6
★★★☆☆3.3/5

Best for: bloodwork inside the $299/month rather than billed on top

Visit MyStart Health

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, He & She MD opens cheaper — $99/mo against $299, and He & She MD finishes ahead, 9.3 to 6.6. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

He & She MD

Platinum injectable, intro (6-mo)Compounded
$139/mo
semaglutide
Platinum oral, intro (6-mo)Compounded
$199/mo
semaglutide
Injectable, 12-month prepayCompounded
$99/mo
semaglutide

⛔ THIS ROW PREVIOUSLY DESCRIBED A "microdose" TIER THAT DOES NOT EXIST. Read live from heandshemd.com/weight-loss on 2026-08-14: the word "microdose" appears NOWHERE on the homepage or the weight-loss page. $99 is Semaglutide Injection, and its own asterisk reads "Price for purchase of 12 months supply" — a twelve-month prepay divided down, which is the LONGEST commitment the clinic sells, not the shortest. The figure was real; the product was invented. The standing month-to-month rate for injectable semaglutide is $199.

StartingCompounded
$199/mo
tirzepatide

Injectable tirzepatide intro $199/mo (regular $289/mo)

MyStart Health

All-inclusive (flat, price-locked across dose escalations)Compounded
$299/mo
semaglutide

Homepage FAQ verbatim: program 'starts at $299/month, excluding any discounts,' all-inclusive (consults, unlimited clinician access, meds, labs, shipping). Promo banner '$150 Off + Lifetime 25% Off' (coupon SELFLOVE25 in funnel URL) but no final promo dollar price published pre-quiz — plan-selection pricing is gated behind a signed medical attestation, so not published.

All-inclusive (flat, price-locked across dose escalations)Compounded
$299/mo
tirzepatide

Same flat $299 all-inclusive program price; tirzepatide offering confirmed via funnel testimonial ('Tirzepatide through MyStart') and FAQ injection instructions ('How to inject compounded tirzepatide'). No oral tirzepatide marketing found on the current site (stored con appears stale). Per-drug tier pricing quiz-gated = not published.

What’s included

He & She MD

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

In the price

MyStart Health

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

In the price

Coaching

Not stated

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

He & She MD

9.3/10

Overall

MyStart Health

6.6/10

Value25%

9.7A
vs
B
4.2

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

8.5A
vs
B
3.5

Accessibility10%

10.0A
vs
B
5.0

Support10%

8.5A
vs
B
8.5

Features & Coverage

FeatureHe & She MDMyStart Health
Starting Price$99/mo$299/mo
Features8 features6 features
States Available50Not disclosed
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNone1 warning

About He & She MD

GLP-1 Platinum opens at $139/month as an introductory rate on injectables, then settles at $199. That buys expedited delivery at no cost, board-certified clinicians reachable without limit, GLP-1 coaching and progress tracking inside the app, and billing only happens if a prescription is actually written. He & She MD works nationwide with doctor-prescribed compounded semaglutide and tirzepatide, injectable or oral, a microdose option, and access under brand names to Wegovy, Ozempic and Zepbound. Every state receives shipments except Louisiana. Certification is LegitScript.

Read our full He & She MD review →

About MyStart Health

MyStart Health charges $299/month all-inclusive for compounded semaglutide and tirzepatide, with a price-lock guarantee, same-day physician consultations, and 24/7 care team access. It is LegitScript certified and structured as a Delaware MSO partnering with licensed US clinicians. What it does best is speed of onboarding.

Read our full MyStart Health review →

Pros & Cons

He & She MD

What we like

  • Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly figure covers medication, consult, shipping, coaching
  • Coverage is published for all 50 states
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

MyStart Health

What we like

  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
  • The monthly figure covers medication, consult, shipping, labs

Watch-outs

  • Semaglutide at $299 a month, 58% above the $189 register median for the same drug and form
  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • 1 FDA warning letter matched to this operator in our enforcement register — read what the letter alleges, since a letter discloses a problem rather than disqualifying a seller
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: He & She MD

He & She MD takes it, 9.3 against 6.6, and it is especially strong on starting below a standard dose, with microdose tiers. MyStart Health is no weak second and may fit you better on bloodwork inside the $299/month rather than billed on top.

Choose He & She MD if…

You want starting below a standard dose, with microdose tiers and an opening price near $99 a month.

Choose MyStart Health if…

You want bloodwork inside the $299/month rather than billed on top and an opening price near $299 a month.

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He & She MD vs MyStart Health: FAQ

Glossary

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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.