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Enhance MD vs Immortals

Immortals costs $2 less a month, and both sell semaglutide and tirzepatide.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
Enhance MD logo

Enhance MD

8.4
★★★★☆4.2/5

Best for: knowing which pharmacy fills the vial: it names Tru Meds Rx

Visit Enhance MD →
VS
Immortals logo

Immortals

6.6
★★★☆☆3.3/5

Best for: starting below a standard dose, with microdose tiers

Visit Immortals →

If you are choosing between Enhance MD and Immortals, the first difference is cost: Immortals is $2 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Enhance MD leads our six-part score, 8.4 to 6.6.

Enhance MD vs Immortals price

Immortals is the cheaper way in: $167 a month against $169 a month at Enhance MD. That is $2 less each month (1% lower), or about $24 over a year of treatment.

Drug by drug: Semaglutide is cheaper at Immortals ($167 a month vs $212 a month); tirzepatide is cheaper at Enhance MD ($169 a month vs $180 a month).

Medications and formats

Both sell semaglutide and tirzepatide.

On format they match: each offers compounded injections.

Where each one treats patients

Enhance MD lists 39 states, and Immortals does not publish where it ships.

Pricing

Enhance MD

GLP-1 CoreCompounded
$212$112/mo
Save 47% right now
semaglutide

$212/mo is the 12-month-plan rate (billed every 48 weeks). 6-mo $224/mo, 3-mo $237/mo, 1-mo $249/mo. First month $112 = $100 off first order on 3+ month plans (code SUMMER100); $50 off 1-month (SUMMER50). Flat price at all doses; labs, consult, 2-day shipping included.

GLP-1 AdvancedCompounded
$280$180/mo
Save 36% right now
tirzepatide

$280/mo = 12-month-plan rate. 6-mo $296/mo, 3-mo $313/mo, 1-mo $329/mo. First month $180 via $100-off first order (SUMMER100). Flat all-dose pricing.

GLP-1 Elite (sema + tirz)Compounded
$322$222/mo
Save 31% right now
tirzepatide

Combined semaglutide + tirzepatide. $322/mo = 12-month-plan rate. 6-mo $341/mo, 3-mo $360/mo, 1-mo $379/mo. First month $222 via SUMMER100.

Microdosing Tirzepatide (NEW product)Compounded
$169/mo
tirzepatide

New low-dose tier: 12-mo $169/mo, 6-mo $179/mo, 3-mo $189/mo; the 1-month plan's price is not displayed on the page (blank slot) — not published. No $100-off promo tags shown on this product's plan picker.

Immortals

MicrodoseCompounded
$167/mo
semaglutide

From $167/mo, a promotional price (regular $245/month). Compounded semaglutide with glycine and B12. Billed quarterly: $501 up front for a 3-month commitment. No added fees beyond the subscription.

MicrodoseCompounded
$180/mo
tirzepatide

From $180/mo, a promotional price (regular $265/month). Compounded tirzepatide with glycine and B12. Billed quarterly: $540 up front for a 3-month commitment. No added fees beyond the subscription.

What each price covers

Both prices cover the clinician visit and the medication itself.

Enhance MD's price also covers lab work, which Immortals does not claim.

Immortals' price also covers shipping, which Enhance MD does not claim.

Enhance MD is silent on shipping and coaching.

Immortals is silent on lab work and coaching.

Enhance MD

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

Not stated

Lab work

In the price

Coaching

Not stated

Immortals

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall, Enhance MD scores 8.4 and Immortals 6.6 out of 10.

Enhance MD is stronger on user experience (7.0 vs 3.0), trust & safety (9.0 vs 4.0) and accessibility (8.2 vs 5.0).

Value, effectiveness and support are within half a point.

How we score

Enhance MD

8.4/10

Overall

Immortals

6.6/10

Value25%

7.8A
vs
B
7.4

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

7.0A
vs
B
3.0

Trust & Safety15%

9.0A
vs
B
4.0

Accessibility10%

8.2A
vs
B
5.0

Support10%

7.0A
vs
B
7.0

FDA warning letters

Neither Enhance MD nor Immortals has an FDA warning letter on record with us.

Features & Coverage

FeatureEnhance MDImmortals
Starting Price$169/mo✓$167/mo
Features6 features✓8 features
States Available39Not disclosed
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA Warning LettersNoneNone

About Enhance MD

$112 buys the first month on Core, once $100 comes off the opening order with code SUMMER100. Core is the semaglutide tier, Advanced is tirzepatide, Elite combines the two. Before any of that, Enhance MD requires two mandatory steps: baseline metabolic labs, drawn at Quest Diagnostics, then a live video visit with a board-certified clinician. Most sellers in compounded GLP-1s onboard asynchronously and ask for neither, so this is the more rigorous route in.

Read our full Enhance MD review →

About Immortals

Quarterly billing, and both figures are promotional: $167/month on semaglutide, $180/month on tirzepatide. Bryan Johnson founded the longevity service, which is LegitScript-certified and sells microdose weekly injections of Tirzepatide/Glycine/B12 and Semaglutide/Glycine/B12 in compounded form. 12 months of unlimited messaging with a provider, discreet shipping, fulfillment by U.S. pharmacies holding licenses, and a physician review inside 72 hours come with the subscription. Insurance is not required, and HSA/FSA money is reimbursable.

Read our full Immortals review →

Pros & Cons

Enhance MD

What we like

  • Semaglutide costs $212 a month, close to the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $169 a month, 32% below the $250 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price stays the same as your dose goes up
  • The monthly price includes the medication, clinician visits and lab work
  • Names 3 pharmacies that fill its prescriptions, which most sellers do not
  • We found no FDA warning letters issued to Enhance MD
  • A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
  • Baseline bloodwork is required before a prescription

Watch-outs

  • Serves only 39 states, so check that yours is one of them
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Immortals

What we like

  • Semaglutide costs $167 a month, close to the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $180 a month, 28% below the $250 median for compounded tirzepatide across the sellers we compare
  • The monthly price includes the medication, clinician visits and shipping
  • We found no FDA warning letters issued to Immortals

Watch-outs

  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Enhance MD

Enhance MD wins this one, 8.4 to 6.6, above all for knowing which pharmacy fills the vial: it names Tru Meds Rx. Immortals undercuts it by $2 a month, so if the monthly bill is what decides it, Immortals is the pick. Immortals fits better if starting below a standard dose, with microdose tiers is your priority.

Choose Enhance MD if…

You want knowing which pharmacy fills the vial: it names Tru Meds Rx and an opening price near $169 a month.

Choose Immortals if…

You want starting below a standard dose, with microdose tiers and an opening price near $167 a month.

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8.4

Enhance MD

Knowing which pharmacy fills the vial: it names Tru Meds Rx

6.1

DudeMeds

Compounded semaglutide at $175/month

7.8

Oak

Semaglutide at $119/month, 37% below the typical price

Enhance MD vs Immortals: FAQ

Immortals. It starts at $167 a month; Enhance MD starts at $169 a month, $2 more per month.
Yes, both sell semaglutide and tirzepatide.
Enhance MD lists 39 states; Immortals does not publish where it ships. Confirm your state before paying.
Both include the clinician visit and the medication itself. Only Enhance MD includes lab work. Only Immortals includes shipping.
Enhance MD has none. Immortals has none.
Enhance MD pays us a commission on sign-ups through our links; Immortals does not. Scores are computed the same way for both.

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