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CoreAge Rx vs Cost Plus Drugs

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
CoreAge Rx logo

CoreAge Rx

9.1
★★★★4.6/5

Best for: semaglutide at $99/month, 48% under the register median

Visit CoreAge Rx
VS
Cost Plus Drugs logo

Cost Plus Drugs

6.5
★★★☆☆3.3/5

Best for: coverage in all 50 states, which most of the register will not confirm

Visit Cost Plus Drugs

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, CoreAge Rx opens cheaper — $99/mo against $279, and CoreAge Rx finishes ahead, 9.1 to 6.5. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

CoreAge Rx

Injectable, monthly auto-refill (flat across all dosages)Compounded
$99/mo
semaglutide

Re-verified 2026-08-05: homepage + Preventive Longevity section both show "Semaglutide — Starting at $99/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Injectable, monthly auto-refill (flat across all dosages)Compounded
$149/mo
tirzepatide

Re-verified 2026-08-05: homepage GLP-1 hero + Preventive Longevity section both show "Tirzepatide — Starting at $149/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Cost Plus Drugs

Ozempic (branded, WAC + 15% + $5 pharmacy fee)Brand-name
$279/mo
semaglutide

What’s included

CoreAge Rx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Cost Plus Drugs

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

CoreAge Rx

9.1/10

Overall

Cost Plus Drugs

6.5/10

Value25%

9.7A
vs
B
5.0

Effectiveness25%

10.0A
vs
B
9.0

User Experience15%

8.0A
vs
B
5.0

Trust & Safety15%

8.5A
vs
B
5.0

Accessibility10%

10.0A
vs
B
10.0

Support10%

7.0A
vs
B
5.0

Features & Coverage

FeatureCoreAge RxCost Plus Drugs
Starting Price$99/mo$279/mo
Features6 features5 features
States Available5050
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About CoreAge Rx

Shipping is free, 2-day, and reaches all 50 states. CoreAge Rx sells LegitScript-verified compounded semaglutide plus tirzepatide, with licensed physicians behind it and 24/7 support. Its own claim: nobody in the compounded GLP-1 space prices more competitively.

Read our full CoreAge Rx review →

About Cost Plus Drugs

Cost Plus Drugs is Mark Cuban's transparent-pricing online pharmacy. It sells branded Ozempic at the wholesale acquisition cost plus a 15% markup and a flat $5 pharmacy fee, a margin formula it discloses publicly. There is no telehealth intake; this is pharmacy fulfillment only, shipping to all 50 states. Telehealth platforms that route brand-name semaglutide through similar discount channels are a separate category.

Read our full Cost Plus Drugs review →

Pros & Cons

CoreAge Rx

What we like

  • Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
  • Tirzepatide at $149 a month, 44% below the $267 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
  • The monthly figure covers medication, consult, shipping
  • Coverage is published for all 50 states
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Cost Plus Drugs

What we like

  • Semaglutide at $279 a month, 79% below the $1299 median for the same drug and form across this register
  • Coverage is published for all 50 states
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here

Our Verdict

Winner: CoreAge Rx

CoreAge Rx takes it, 9.1 against 6.5, and it is especially strong on semaglutide at $99/month, 48% under the register median. Cost Plus Drugs is no weak second and may fit you better on coverage in all 50 states, which most of the register will not confirm.

Choose CoreAge Rx if…

You want semaglutide at $99/month, 48% under the register median and an opening price near $99 a month.

Choose Cost Plus Drugs if…

You want coverage in all 50 states, which most of the register will not confirm and an opening price near $279 a month.

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MyDrHank

An oral route if you will not self-inject

6.0

SkinnyRx

Starting below a standard dose, with microdose tiers

9.4

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Knowing which pharmacy fills the vial — it names VialsRx

CoreAge Rx vs Cost Plus Drugs: FAQ

Glossary

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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.