Cielo vs Wholesome Clinic
Wholesome Clinic costs $6 less a month, and both sell semaglutide and tirzepatide.
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Wholesome Clinic
Best for: semaglutide at $109/month, 42% below the typical price
Visit Wholesome Clinic →If you are choosing between Cielo and Wholesome Clinic, the first difference is cost: Wholesome Clinic is $6 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Cielo leads our six-part score, 7.7 to 7.6.
Cielo vs Wholesome Clinic price
Wholesome Clinic is the cheaper way in: $109 a month against $115 a month at Cielo. That is $6 less each month (5% lower), or about $72 over a year of treatment.
Drug by drug: Semaglutide is cheaper at Wholesome Clinic ($109 a month vs $115 a month); tirzepatide is cheaper at Cielo ($180 a month vs $249 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format they match: each offers compounded injections.
Where each one treats patients
Cielo does not publish where it ships, and Wholesome Clinic lists 7 states.
Pricing
Cielo
Wholesome Clinic
Self-pay; $109/$149/$199 per month by dose plan
Self-pay; $149-$199+ per month by dose plan
Self-pay; $249/$299/$349 per month by dose plan
Self-pay; $349/$449/$549 per month by dose plan
What each price covers
Both prices cover the medication itself.
Cielo's price also covers shipping, which Wholesome Clinic does not claim.
Cielo is silent on the clinician visit, lab work and coaching.
Wholesome Clinic is silent on shipping, lab work and coaching.
Cielo
Covered by the monthly price
Medication
In the price
Clinician visits
Not stated
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Wholesome Clinic
Covered by the monthly price
Medication
In the price
Clinician visits
Charged on top
Shipping
Not stated
Lab work
Not stated
Coaching
Not stated
Where each one scores higher
Overall, Cielo scores 7.7 and Wholesome Clinic 7.6 out of 10.
Cielo is stronger on user experience (8.0 vs 7.0), accessibility (5.0 vs 3.1) and support (4.5 vs 3.0).
Wholesome Clinic is stronger on trust & safety (8.5 vs 6.5).
Value and effectiveness are within half a point.
Cielo
7.7/10
Wholesome Clinic
7.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
Neither Cielo nor Wholesome Clinic has an FDA warning letter on record with us.
Features & Coverage
| Feature | Cielo | Wholesome Clinic |
|---|---|---|
| Starting Price | $115/mo | ✓$109/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 7 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | None | None |
About Cielo
Cielo starts semaglutide at $115/month and tirzepatide at $180/month on a 3-month bundle, flat at every dose. It carries compounded GLP-1s only: no brand-name drugs, no TRT, hair or mental-health add-ons, which makes it a focused, single-purpose alternative to multi-vertical sellers. Clinical care is delivered through MD Integrations.
Read our full Cielo review →About Wholesome Clinic
Medication paid out of pocket opens at $109/month for compounded semaglutide, while a $149 first evaluation and $75 follow-ups are billed on their own. Seven states can reach the telehealth weight-loss service, run from an integrative-psychiatry and wellness practice in Frisco, Texas, where providers write weekly injectables or oral dissolving tablets of compounded tirzepatide and semaglutide, turning to Zepbound and Wegovy under brand names where clinically appropriate.
Read our full Wholesome Clinic review →Pros & Cons
Cielo
What we like
- Semaglutide costs $115 a month, 38% below the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $180 a month, 28% below the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price stays the same as your dose goes up
- The monthly price includes the medication and shipping
- We found no FDA warning letters issued to Cielo
Watch-outs
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Wholesome Clinic
What we like
- Semaglutide costs $109 a month, 41% below the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $249 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication
- We found no FDA warning letters issued to Wholesome Clinic
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
- Baseline bloodwork is required before a prescription
Watch-outs
- Not included in the monthly price: clinician visits
- Serves only 7 states, so check that yours is one of them
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Cielo wins this one, 7.7 to 7.6, above all for semaglutide at $115/month, 39% below the typical price. Wholesome Clinic undercuts it by $6 a month, so if the monthly bill is what decides it, Wholesome Clinic is the pick. Wholesome Clinic fits better if semaglutide at $109/month, 42% below the typical price is your priority.
Choose Cielo if…
You want semaglutide at $115/month, 39% below the typical price and an opening price near $115 a month.
Choose Wholesome Clinic if…
You want semaglutide at $109/month, 42% below the typical price and an opening price near $109 a month.
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