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California Trim Clinic vs HumeCare+

California Trim Clinic and HumeCare+ both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
California Trim Clinic logo

California Trim Clinic

5.9
★★★☆☆3/5
Visit California Trim Clinic →
VS
HumeCare+ logo

HumeCare+

5.7
★★★☆☆2.9/5

Best for: an oral route if you will not self-inject

Visit HumeCare+ →

If you are choosing between California Trim Clinic and HumeCare+, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. California Trim Clinic leads our six-part score, 5.9 to 5.7.

California Trim Clinic vs HumeCare+ price

California Trim Clinic and HumeCare+ start at the same figure, $199 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.

Drug by drug: Semaglutide costs the same at both, $199 a month on a prepaid plan; tirzepatide costs the same at both, $299 a month on a prepaid plan.

Medications and formats

Both sell semaglutide and tirzepatide.

On format, California Trim Clinic prices compounded injections, while HumeCare+ prices compounded injections and an oral option.

Where each one treats patients

California Trim Clinic says it treats patients nationwide but does not list states, and HumeCare+ does not publish where it ships.

Pricing

California Trim Clinic

Injectable — 3-month commitment requiredCompounded
$199/mo
semaglutide
Injectable — 3-month commitment requiredCompounded
$299/mo
tirzepatide

HumeCare+

Compounded semaglutide injectionCompounded
$199/mo
semaglutide

Shown at checkout after the intake questionnaire: $199/mo charged, with $299 struck through and 'SAVE $100.' HumeCare+ does not say whether $299 is a regular rate anyone pays or only a reference price.

Compounded tirzepatide + vitamin B12 + glycineCompounded
$299/mo
tirzepatide

At checkout after intake: $299/mo charged, $399 struck through. Sold as a combination with vitamin B12 and glycine rather than tirzepatide alone.

Oral compounded semaglutideCompounded · oral
$199/mo
semaglutide

At checkout after intake: $199/mo charged, $299 struck through.

What each price covers

Both prices cover the clinician visit and the medication itself.

California Trim Clinic's price also covers shipping, which HumeCare+ does not claim.

HumeCare+ is silent on shipping, lab work and coaching.

California Trim Clinic

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Charged on top

Coaching

Charged on top

HumeCare+

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

Not stated

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall, California Trim Clinic scores 5.9 and HumeCare+ 5.7 out of 10.

California Trim Clinic is stronger on support (7.0 vs 5.5).

Value, effectiveness, user experience, trust & safety and accessibility are within half a point.

How we score

California Trim Clinic

5.9/10

Overall

HumeCare+

5.7/10

Value25%

4.5A
vs
B
4.5

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

3.0A
vs
B
3.0

Trust & Safety15%

4.0A
vs
B
4.0

Accessibility10%

5.0A
vs
B
5.0

Support10%

7.0A
vs
B
5.5

FDA warning letters

Neither California Trim Clinic nor HumeCare+ has an FDA warning letter on record with us.

Features & Coverage

FeatureCalifornia Trim ClinicHumeCare+
Starting Price$199/mo prepaid$199/mo
Features8 features8 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA Warning LettersNoneNone

About California Trim Clinic

The $199 initial plan buys the doctor consultation, telehealth setup and onboarding; ongoing 3-month treatment plans include compounded medication and provider check-ins, with that pricing discussed only after approval. This is a Westlake Village, CA peptide and longevity clinic running a 100% virtual, nationwide GLP-1 program through licensed US providers, specializing in compounded semaglutide and tirzepatide. It also runs a Women's Microdosing & Weight Maintenance program aimed at perimenopause and menopause-related weight challenges.

Read our full California Trim Clinic review →

About HumeCare+

Plans open from $199/mo, billed month by month and cancellable whenever, and both the drug and the hardware sit inside that. HumeCare+ comes from Hume Health, the company that sells body-composition scales, and the logic follows: clinician-prescribed compounded GLP-1 semaglutide arrives with a Hume Pod, so the patient can watch whether the weight leaving is fat or muscle. Which states it serves is unpublished, and the marketing site identifies neither the prescribing medical group nor the pharmacy.

Read our full HumeCare+ review →

Pros & Cons

California Trim Clinic

What we like

  • Semaglutide costs $199 a month, close to the $185 median for compounded semaglutide across the sellers we compare
  • The monthly price includes the medication, clinician visits and shipping
  • We found no FDA warning letters issued to California Trim Clinic

Watch-outs

  • Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Not included in the monthly price: lab work, coaching
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

HumeCare+

What we like

  • Semaglutide costs $199 a month, close to the $185 median for compounded semaglutide across the sellers we compare
  • The monthly price includes the medication and clinician visits
  • We found no FDA warning letters issued to HumeCare+
  • Offers both oral and injectable options, so the format is your choice

Watch-outs

  • Tirzepatide costs $299 a month, 20% above the $250 median for compounded tirzepatide across the sellers we compare
  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: HumeCare+

HumeCare+ is where we would start, above all for an oral route if you will not self-inject.

Choose California Trim Clinic if…

You want the lower starting price and an opening price near $199 a month.

Choose HumeCare+ if…

You want an oral route if you will not self-inject and an opening price near $199 a month.

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California Trim Clinic vs HumeCare+: FAQ

Neither on the entry price: California Trim Clinic and HumeCare+ both start at about $199 a month. The difference is in what the price includes.
Yes, both sell semaglutide and tirzepatide.
California Trim Clinic says it treats patients nationwide but does not list states; HumeCare+ does not publish where it ships. Confirm your state before paying.
Both include the clinician visit and the medication itself. Only California Trim Clinic includes shipping.
California Trim Clinic has none. HumeCare+ has none.
HumeCare+ pays us a commission on sign-ups through our links; California Trim Clinic does not. Scores are computed the same way for both.

Or see the full category ranking.