GLP Watchdog

Actin vs PlushCare

Neither Actin nor PlushCare has an FDA warning letter on record. On compounded tirzepatide injection, Actin costs $1,560 less a year at standing rates: $269 a month against $399 a month at PlushCare.

By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed

The record

Actin / PlushCare

Actin logo

Actin

6.5/10

PlushCare logo

PlushCare

6.4/10

FDA warning letters
None on record
None on record
Pharmacy
None named in our record
Lowest standing price
$149/moCompounded semaglutide injection
$149/moCompounded semaglutide injection
States
No state list published
All 50 states
Checked
Prices captured Record checked October 2026
Prices captured Record checked September 2026
Visit ActinFull review
Visit PlushCareFull review

Neither Actin nor PlushCare pays us. Links to them earn nothing. Scores: Actin 6.5, PlushCare 6.4. How we are paid

What the record shows

  1. 01

    Neither Actin nor PlushCare has an FDA warning letter on record.

  2. 02

    Actin names three pharmacies, all 503A. PlushCare names no compounding pharmacy in our record.

  3. 03

    On compounded tirzepatide injection, Actin costs $1,560 less a year at standing rates: $269 a month against $399 a month at PlushCare.

  4. 04

    PlushCare lists all 50 states. Actin publishes no state list.

Prices and terms, product by product

A price is set against the other side only for the same product, and only when both are standing monthly or 4-week rates. Those pairs are compared by yearly cost.

Actin

PlushCare

Compounded semaglutide injection

$149/mo

$1,788 a year

$149/mo

$1,788 a year

Compounded tirzepatide injection

$269/moLower

$3,228 a year

$399/mo

$4,788 a year

Price includes
Medication, shipping
Not stated
Billed separately
Not stated
Medication, clinician visits, labs
Cancel any time
Yes, stated
Yes, stated
Minimum term
None month to month; the longer terms are paid in advance
None; membership is billed monthly or annually
Refunds
No refunds: the terms make every sale final, including subscription charges.
Appointment cost only; membership fees and prescriptions are not refunded
Early-exit fee
None stated
Not stated

Read off each seller’s own pages. Actin: October 17, 2026. PlushCare: July 10, 2026. Every plan and dose we hold is on the full review.

The case for each

The case for Actin

6.5/10
  • $1,560 a year less on compounded tirzepatide injection
  • Names its compounding pharmacy
  • Publishes no state list
Visit Actin

The case for PlushCare

6.4/10

The record gives PlushCare no edge on this pair.

  • Names no compounding pharmacy
  • Price leaves out medication, clinician visits and labs
Visit PlushCare

Scores

Actin 6.5 · PlushCare 6.4 out of 10. Six weighted parts.

Value25%

7.1A
vs
B
3.0

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

3.0A
vs
B
7.0

Trust & Safety15%

5.5A
vs
B
7.5

Accessibility10%

5.0A
vs
B
10.0

Support10%

4.5A
vs
B
0.0

The score is the same formula for every seller. Payment does not enter it. Method

Actin vs PlushCare: questions

Neither Actin nor PlushCare has an FDA warning letter on record. Letters are matched to a seller by company, domain and address, never by a similar name.
Actin names three pharmacies, all 503A. PlushCare names no compounding pharmacy in our record. A 503A pharmacy compounds for named patients on a prescription; a 503B outsourcing facility is registered with FDA and inspected under federal manufacturing rules.
Actin, by $1,560 a year at standing rates. Actin: $269 a month, about $3,228 a year. PlushCare: $399 a month, about $4,788 a year.
Actin states you can cancel at any time; refunds: no refunds: the terms make every sale final, including subscription charges. PlushCare states you can cancel at any time; refunds: appointment cost only; membership fees and prescriptions are not refunded.
Neither Actin nor PlushCare pays us. Links to them earn nothing. Scores: Actin 6.5, PlushCare 6.4.

Other sellers we are paid by

Affiliate partners outside this pair. Each has its own record and review, scored the same way.

Sellers closest to these two

Matched on molecule, form and price. Every pair we list · The register