1st Optimal vs Superior Remedies
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: coaching bundled into the price rather than sold separately
Visit 1st Optimal →
Superior Remedies
Best for: starting below a standard dose, with microdose tiers
Visit Superior Remedies →Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, Superior Remedies starts at $249/mo, and Superior Remedies finishes ahead, 6.4 to 3.9. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
1st Optimal
Pricing not publicly listed.
Superior Remedies
Semaglutide program, listed at $299/mo on the treatment page
Tirzepatide program, listed at $399/mo on the treatment page
GLP-1 Microdose program at $249/mo; the site never says which molecule it uses
What’s included
1st Optimal
Covered by the monthly price
Medication
Not stated
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
Superior Remedies
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
3.9/10
Superior Remedies
6.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Superior Remedies |
|---|---|---|
| Starting Price | — | $249/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | 7 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
Neither a monthly price nor a list of states is published. 1st Optimal operates out of Michigan across telehealth and functional medicine, writing the GLP-1s semaglutide and tirzepatide either as a weekly injection or as a daily oral tablet. Around the prescription it stacks at-home lab testing, interpretation of the blood work, coaching without limit and protocols built individually, all framed as long-term weight loss and longevity. Credentialed providers work virtually, treatment goes to the home, and nothing binds you to a long contract.
Read our full 1st Optimal review →About Superior Remedies
Approval comes first and payment second: if no provider signs off, nothing is charged. The monthly rate is flat, with neither a consultation fee nor a surcharge when the dose changes. Semaglutide, tirzepatide and a reduced-dose microdose protocol, the last aimed at body composition instead of the largest possible weight loss, are all supervised by a provider. Registration is in Delaware. Note the contradiction across its own pages: the banner on the homepage claims 50 states, while the FAQ caps service at seven.
Read our full Superior Remedies review →Pros & Cons
1st Optimal
What we like
- The monthly figure covers consult, shipping, coaching
- No FDA warning letter matched this operator when we searched our enforcement register
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
- Baseline bloodwork is required before a prescription
Watch-outs
- No price appears until the medical intake is complete, so the cost cannot be compared before health information is submitted
- No state list is on record here, so whether it serves your state cannot be confirmed from this page
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
Superior Remedies
What we like
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
- The monthly figure covers medication, consult, shipping
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- Semaglutide at $299 a month, 58% above the $189 register median for the same drug and form
- Tirzepatide at $399 a month, 49% above the $267 register median for the same drug and form
- Coverage is published for 7 states only, so this may not reach you
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Superior Remedies takes it, 6.4 against 3.9, and it is especially strong on starting below a standard dose, with microdose tiers. 1st Optimal is no weak second and may fit you better on coaching bundled into the price rather than sold separately.
Choose 1st Optimal if…
You want coaching bundled into the price rather than sold separately.
Choose Superior Remedies if…
You want starting below a standard dose, with microdose tiers and an opening price near $249 a month.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
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YourEra
Semaglutide at $99/month, 63% under the register median
From $99/mo
Get started →Gala
Moving between compounded and brand without changing seller
From $129/mo
Get started →Trimi Health
Knowing which pharmacy fills the vial — it names VialsRx
From $99/mo
Get started →1st Optimal vs Superior Remedies: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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- Superior Remedies vs Lean Meds
- Superior Remedies vs NextMeds
- Superior Remedies vs bmiMD
Or see the full category ranking.
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