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10rx vs Primary Clinic (Direct GLP)

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

8.1
★★★★4.1/5

Best for: semaglutide at $99.67/month, 47% under the register median

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VS
Primary Clinic (Direct GLP) logo

Primary Clinic (Direct GLP)

6.6
★★★☆☆3.3/5

Best for: seeing what it charges before you answer any medical questions

Visit Primary Clinic (Direct GLP)

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, Primary Clinic (Direct GLP) opens cheaper — $65/mo against $99.67, and 10rx finishes ahead, 8.1 to 6.6. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

Primary Clinic (Direct GLP)

0.25 mg / 0.5 mg (member wholesale)Compounded
$65/mo
semaglutide
1 mg (member wholesale)Compounded
$85/mo
semaglutide
1.7 mg (member wholesale)Compounded
$122/mo
semaglutide
2.7 mg (member wholesale)Compounded
$160/mo
semaglutide
2.5 mg (member wholesale)Compounded
$110/mo
tirzepatide
5 mg (member wholesale)Compounded
$160/mo
tirzepatide
7.5 mg (member wholesale)Compounded
$210/mo
tirzepatide
10 mg (member wholesale)Compounded
$235/mo
tirzepatide

What’s included

10rx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Primary Clinic (Direct GLP)

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

8.1/10

Overall

Primary Clinic (Direct GLP)

6.6/10

Value25%

9.6A
vs
B
3.0

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

5.5A
vs
B
8.5

Accessibility10%

5.0A
vs
B
3.6

Support10%

7.0A
vs
B
5.0

Features & Coverage

Feature10rxPrimary Clinic (Direct GLP)
Starting Price$99.67/mo$65/mo
Features8 features4 features
States AvailableNot disclosed10
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx sets flat monthly rates on compounded GLP-1: semaglutide at $99.67, tirzepatide at $149.67, with NAD+ and sermorelin sold separately for energy and recovery. A free health quiz online reaches a board-certified telehealth doctor, who reads your history before writing anything, and licensed pharmacy partners handle discreet delivery. The company states it reaches every one of the 50 states. What it does not state is its operating company, its pharmacies, or any terms page.

Read our full 10rx review →

About Primary Clinic (Direct GLP)

What is sold here is Direct Primary Care membership, not a GLP-1 package. $89/mo covers primary care without limit, texting the clinic directly, virtual visits the same day and routine labs. Members then purchase compounded 503A GLP-1s at wholesale, no markup applied: $65/mo and up for semaglutide, $110/mo and up for tirzepatide. It runs in 10 states so far, and monitoring of the medication happens inside a continuing care relationship.

Read our full Primary Clinic (Direct GLP) review →

Pros & Cons

10rx

What we like

  • Semaglutide at $99.67 a month, 47% below the $189 median for the same drug and form across this register
  • Tirzepatide at $149.67 a month, 44% below the $267 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly figure covers medication, consult, shipping
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Primary Clinic (Direct GLP)

What we like

  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • Coverage is published for 10 states only, so this may not reach you
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: 10rx

10rx takes it, 8.1 against 6.6, and it is especially strong on semaglutide at $99.67/month, 47% under the register median. Primary Clinic (Direct GLP) is no weak second and may fit you better on seeing what it charges before you answer any medical questions.

Choose 10rx if…

You want semaglutide at $99.67/month, 47% under the register median and an opening price near $99.67 a month.

Choose Primary Clinic (Direct GLP) if…

You want seeing what it charges before you answer any medical questions and an opening price near $65 a month.

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10rx vs Primary Clinic (Direct GLP): FAQ

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