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10rx vs MadeMed

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

8.1
★★★★4.1/5

Best for: semaglutide at $99.67/month, 47% under the register median

Visit 10rx
VS
MadeMed logo

MadeMed

6.5
★★★☆☆3.3/5

Best for: compounded semaglutide at $239/month

Visit MadeMed

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, 10rx opens cheaper — $99.67/mo against $219, and 10rx finishes ahead, 8.1 to 6.5. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

MadeMed

Injectable — Starting (billed quarterly, flat at every dose)Compounded
$239/mo
semaglutide

Quarterly plan $239/mo (billed $717/3mo); 6-month plan drops to $199/mo (the site's 'From $199/mo'). Includes L-Carnitine; 2-month supplies.

Injectable — Starting (billed quarterly, flat at every dose)Compounded
$399/mo
tirzepatide

Quarterly $399/mo (billed $1,197/3mo); 6-month $369/mo.

Sublingual tablet — Starting (billed quarterly)Compounded · oral
$219/mo
semaglutide

Quarterly $219/mo (billed $657/3mo); 6-month $179/mo. Includes B6.

Sublingual tablet — Starting (billed quarterly)Compounded · oral
$299/mo
tirzepatide

Quarterly $299/mo (billed $897/3mo); 6-month $279/mo.

What’s included

10rx

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

MadeMed

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

8.1/10

Overall

MadeMed

6.5/10

Value25%

9.6A
vs
B
3.3

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

5.5A
vs
B
6.5

Accessibility10%

5.0A
vs
B
5.0

Support10%

7.0A
vs
B
5.0

Features & Coverage

Feature10rxMadeMed
Starting Price$99.67/mo$219/mo
Features8 features6 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx sets flat monthly rates on compounded GLP-1: semaglutide at $99.67, tirzepatide at $149.67, with NAD+ and sermorelin sold separately for energy and recovery. A free health quiz online reaches a board-certified telehealth doctor, who reads your history before writing anything, and licensed pharmacy partners handle discreet delivery. The company states it reaches every one of the 50 states. What it does not state is its operating company, its pharmacies, or any terms page.

Read our full 10rx review →

About MadeMed

Nothing is priced in public at MadeMed; the number waits inside the product pages or the checkout. Its catalog runs to four distinct products, compounded semaglutide and compounded tirzepatide, each offered as an injection or by mouth, so patients who dislike needles get more choice here than most rivals allow. A LegitScript certification badge is displayed, and unlike chat-only competitors it publishes a phone line for support.

Read our full MadeMed review →

Pros & Cons

10rx

What we like

  • Semaglutide at $99.67 a month, 47% below the $189 median for the same drug and form across this register
  • Tirzepatide at $149.67 a month, 44% below the $267 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly figure covers medication, consult, shipping
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

MadeMed

What we like

  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • Tirzepatide at $399 a month, 49% above the $267 register median for the same drug and form
  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: 10rx

10rx takes it, 8.1 against 6.5, and it is especially strong on semaglutide at $99.67/month, 47% under the register median. MadeMed is no weak second and may fit you better on compounded semaglutide at $239/month.

Choose 10rx if…

You want semaglutide at $99.67/month, 47% under the register median and an opening price near $99.67 a month.

Choose MadeMed if…

You want compounded semaglutide at $239/month and an opening price near $219 a month.

Ready to start? Vetted GLP-1 providers

Vetted telehealth providers that prescribe GLP-1 online.

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7.0

MyDrHank

An oral route if you will not self-inject

6.0

SkinnyRx

Starting below a standard dose, with microdose tiers

8.2

YourEra

Semaglutide at $99/month, 63% under the register median

10rx vs MadeMed: FAQ

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