13 articles
Weight-loss supplements and diet trends: what the trials show
Most products sold as a natural GLP-1 or a fat burner have been tested, and most failed or moved weight by a pound or two. These articles give the trial numbers first, then the safety record and the regulatory status, and say plainly where no study exists.
GLP-1 Supplements: Do Berberine, Lemon Extract and Probiotics Work?
GLP-1 supplements contain no GLP-1. Berberine averaged 0.88 kg more weight lost than control across 23 trials; a lemon flavonoid raised GLP-1 15% with no weight change; saffron did nothing significant. Semaglutide: 12.7 kg. What the label may legally claim.
10 min read · 20 citationsAkkermansia muciniphila: What the Human Trials Show About Weight and GLP-1
Akkermansia is sold as a natural GLP-1 booster. Seven small randomized trials exist: one cut weight regain by about 2 kg, the largest missed its primary endpoint, and most were run by the maker. EU authorization, US status, and what GLP-1 drugs do to it.
11 min read · 21 citationsGarcinia Cambogia: What the Weight-Loss and Liver Evidence Shows
Garcinia cambogia does not produce meaningful weight loss. In the 1998 JAMA trial, people on hydroxycitric acid lost 3.2 kg vs 4.1 kg on placebo. What the meta-analyses, liver-injury registry, Hydroxycut recall and FTC cases show.
11 min read · 25 citationsGreen Tea Extract for Weight Loss: A Small Effect and a Liver Risk
Green tea extract barely moves the scale: Cochrane found 0.04 kg against control, and later meta-analyses 0.4 to 1.8 kg, largely tied to caffeine. High-EGCG extracts raised liver enzymes in 6.7% vs 0.7% on placebo, and the EU now caps EGCG below 800 mg a day.
11 min read · 23 citationsDoes CLA Help With Weight Loss? What the Trials and FDA Records Show
CLA (conjugated linoleic acid) supplements beat placebo by about a third of a kilogram across 70 randomized trials, and not at all for fat in the best-run ones. What the meta-analyses, insulin-resistance trials, liver reports and FDA GRAS letters show.
10 min read · 27 citationsRaspberry Ketones for Weight Loss: Never Tested Alone in People
No human trial has tested raspberry ketone on its own. The weight-loss claim rests on mice fed huge doses and two small trials of a capsule that also held caffeine and bitter orange. Toxicity data, a heart case report, and the FTC cases against its marketers.
11 min read · 20 citationsCapsaicin and Capsinoids for Weight Loss: Eight Measures, Eight Nulls
A dose-response meta-analysis of 13 randomized trials and 838 participants found no effect of capsinoids on body weight, BMI, waist circumference, fat mass, fat-free mass, waist-hip ratio, visceral fat or body fat percentage.
5 min read · 2 citationsThe Pink Salt Trick: What It Does and Why It Is Not a Natural Mounjaro
No study has tested the pink salt trick. Nothing in salt, lemon and water acts on GLP-1 receptors. What the water-before-meals trials show, how pink salt compares with table salt, what the sodium does to blood pressure, and the scam ads behind the trend.
10 min read · 18 citationsThe Gelatin Trick for Weight Loss: What the Trials Found
Gelatin is a low-calorie, incomplete protein that curbed hunger a little in short lab studies. The only weight-loss trial found it added nothing over milk protein, and it does not work like Ozempic. Calories, sugar-free jello and the studies behind the trick.
10 min read · 22 citationsLow-Calorie Snacks: What the Evidence Says, and What Changes on a GLP-1
Snacking is weight-neutral in randomized trials; what the snack is made of is not. Energy density, protein snacks and nuts, then why on Ozempic, Wegovy, Mounjaro or Zepbound the better snack packs the most protein into each calorie, with USDA figures.
10 min read · 18 citationsThe Low-FODMAP Diet on a GLP-1: What It Does for IBS and What Is Untested
The low-FODMAP diet has the strongest trial record of any IBS diet, but it was never designed to cause weight loss, and no trial has tested it on Ozempic, Wegovy, Mounjaro or Zepbound side effects. Food swaps, the three phases, and the fiber and eating risks on a GLP-1.
11 min read · 29 citationsDoes Spirulina Help With Weight Loss? What Small Trials Found
Spirulina trials show about 0.8 to 1.9 kg of extra weight loss in small, short studies. It modestly lowers cholesterol and blood pressure, carries little protein at real doses, does not act like a GLP-1, and algae supplements have tested positive for liver toxins.
9 min read · 24 citationsGLP-1 Booster Supplements by Brand: What Is Inside and What Was Tested
What Bioma, Lemme, Inno Shred, HUM Flatter Me Fiber, ColonBroom, Supergut, Pendulum and Nature Made put in their GLP-1 supplements, whether any product was tested in a published trial, and what the evidence shows for each ingredient.
10 min read · 22 citations