Cholelithiasis
What the FDA labels record as adverse events, each one tied back to the evidence it came from.
Definition
Gallstones — listed in Section 5 of every approved GLP-1 label. Wegovy reports 1.6% against 0.7% on placebo; Saxenda 2.2% against 0.8%. The He et al. 2022 meta-analysis pooled the class risk at RR 1.37 (95% CI 1.23–1.52). Rapid weight loss of any cause raises the risk, so this is not unique to the drugs.
GLP-1 + gallbladder/biliary disease →
GLP Watchdog writes these definitions from FDA labels and peer-reviewed PubMed literature. Not one of them is an AI-generated summary.
Other terms under Side effects
Where the evidence lives
- GLP-1 + gallbladder/biliary disease
- The full GLP-1 glossary (149 terms, 8 categories)
- Research articles — written from primary sources
- Tools and calculators
- Compare GLP-1 telehealth providers