Foundayo Dosing & Titration Schedule
Where orforglipron begins, every step it climbs, and where it stops — maintenance and maximum both — read straight off the FDA prescribing information.
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Foundayo Titration Schedule
Each rung of the Foundayo ladder, taken from Dosage & Administration in its FDA label (DailyMed SetID 8ac446c5-feba-474f-a103-23facb9b5c62). The schedule you actually follow is the one your prescriber writes; this is the reference behind it, not advice about your case.
| Step | Dose | When |
|---|---|---|
| 1 | 0.8 mg once daily | Starting dose |
| 2 | 2.5 mg once daily | 30 days or more at 0.8 mg |
| 3 | 5.5 mg once daily | 30 days or more at 2.5 mg |
| 4 | 9 mg once daily | 30 days or more, judged on how you respond and tolerate it |
| 5 | 14.5 mg once daily | 30 days or more, judged on how you respond and tolerate it |
| 6 | 17.2 mg once daily | 30 days or more, judged on how you respond and tolerate it |
Source: Foundayo FDA prescribing information via DailyMed (SetID 8ac446c5-feba-474f-a103-23facb9b5c62), Section 2 Dosage & Administration, read on 2026-06-01. Treat this as a summary: the full label is the document, and your prescriber's instructions are what you follow.
Foundayo Dosing at a Glance
How to titrate safely
Every increase waits at least 30 days at the current dose. One tablet a day, food or no food, swallowed whole — never broken, crushed or chewed — and never more than one in a day.
One rule governs the whole ladder: you only climb if you are tolerating where you already are, and you hold or slow down when side effects flare. Outrunning the label's schedule does not get you results sooner. What it reliably produces is more nausea and more of everything else the gut does in response.
If you miss a dose or can't tolerate a step
Missed a dose? How late is too late is not the same answer for every drug. Read GLP-1 missed-dose rules by drug for what Foundayo specifically allows, before you double up or write the dose off.
Can't tolerate a dose increase? Holding at the current dose, or waiting longer before the next step, is something the label explicitly permits. What each step tends to bring is set out on the Foundayo side effects page, then talk to your prescriber before changing your schedule.
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