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Vyora Wellness vs NextMeds

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Vyora Wellness logo

Vyora Wellness

5.0
★★☆☆2.5/5

Best for: coaching inside the $299/month rather than sold separately

Visit Vyora Wellness
VS
NextMeds logo

NextMeds

9.2
★★★★4.6/5

Best for: semaglutide at $79/month, 59% under the register median

Visit NextMeds

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, NextMeds opens cheaper — $79/mo against $299, and NextMeds finishes ahead, 9.2 to 5.0. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

Vyora Wellness

Compounded Semaglutide (4-week)Compounded
$299/mo
semaglutide
Compounded Tirzepatide (4-week)Compounded
$399/mo
tirzepatide

NextMeds

InjectableCompounded
$79/mo
semaglutide

Compounded Semaglutide Membership, drug included when prescribed, alongside telehealth visits, a care coach, a dietitian and shipping. $79 is the month-to-month rate read from the pricing section on 2026-08-14. The site headline reads 'from $49/mo': that is the 12-month prepaid term divided down, not a monthly price, and the ladder between them is 3-month $76, 6-month $73, 12-month $49. A summer promotion was running with a stated end of August 20, so $79 may itself be discounted.

InjectableCompounded
$109/mo
tirzepatide

Compounded Tirzepatide Membership, drug included when prescribed, alongside telehealth visits, a care coach, a dietitian and shipping. $109 is the month-to-month rate read from the pricing section on 2026-08-14. The advertised 'GLP-1 + GIP: $95' is the 12-month prepaid term divided down; the ladder is 3-month $105, 6-month $100, 12-month $95. A summer promotion was running with a stated end of August 20, so $109 may itself be discounted.

What’s included

Vyora Wellness

Covered by the monthly price

Medication

In the price

Clinician visits

Not stated

Shipping

Not stated

Lab work

Not stated

Coaching

In the price

NextMeds

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

In the price

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Vyora Wellness

5.0/10

Overall

NextMeds

9.2/10

Value25%

2.1A
vs
B
10.0

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

3.0A
vs
B
8.0

Trust & Safety15%

4.0A
vs
B
7.5

Accessibility10%

5.0A
vs
B
10.0

Support10%

4.5A
vs
B
8.5

Features & Coverage

FeatureVyora WellnessNextMeds
Starting Price$299/mo$79/mo
Features5 features8 features
States AvailableNot disclosed50
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About Vyora Wellness

Vyora Wellness sells compounded semaglutide at $299/mo and compounded tirzepatide at $399/mo, both as 4-week subscription plans. LegitScript certified. The price includes GLP-1 nutritional guidance, 24/7 coaching, and community access. A BMI of 25+ is required.

Read our full Vyora Wellness review →

About NextMeds

Membership is a single flat monthly charge, and inside it sit free shipping, a registered dietitian holding a license, a care coach working 1:1, telehealth visits and the drug itself where one is prescribed. Insurance is not billed. A free assessment online goes to a licensed provider, who adds a phone or video consult in states that demand one, then prescribes if it fits. Compounding pharmacies within the Next Meds network, all licensed, ship. Auto-renewal does not exist, cancellation is open, and all 50 states can order compounded tirzepatide and semaglutide.

Read our full NextMeds review →

Pros & Cons

Vyora Wellness

What we like

  • The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
  • The monthly figure covers medication and coaching
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • Semaglutide at $299 a month, 58% above the $189 register median for the same drug and form
  • Tirzepatide at $399 a month, 49% above the $267 register median for the same drug and form
  • No price appears until the medical intake is complete, so the cost cannot be compared before health information is submitted
  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

NextMeds

What we like

  • Semaglutide at $79 a month, 58% below the $189 median for the same drug and form across this register
  • Tirzepatide at $109 a month, 59% below the $267 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
  • The monthly figure covers medication, consult, shipping, coaching
  • Coverage is published for all 50 states
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: NextMeds

NextMeds takes it, 9.2 against 5.0, and it is especially strong on semaglutide at $79/month, 59% under the register median. Vyora Wellness is no weak second and may fit you better on coaching inside the $299/month rather than sold separately.

Choose Vyora Wellness if…

You want coaching inside the $299/month rather than sold separately and an opening price near $299 a month.

Choose NextMeds if…

You want semaglutide at $79/month, 59% under the register median and an opening price near $79 a month.

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Vyora Wellness vs NextMeds: FAQ

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