RxSpan MD vs Trimi Health
An in-depth comparison of two leading GLP-1 Providers
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more

RxSpan MD
Best for: knowing which pharmacy fills the vial — it names Belmar Pharmacy
Visit RxSpan MD →
Trimi Health
Best for: knowing which pharmacy fills the vial — it names VialsRx
Visit Trimi Health →Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, Trimi Health opens cheaper — $99/mo against $249, and Trimi Health finishes ahead, 9.4 to 6.8. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
RxSpan MD
Plan ladder: Monthly $249/mo, 3-mo $219/mo, 6-mo $199/mo, 12-mo $194/mo. Card labeled '(For the first month)'; plan picker shows flat recurring rates (Total if prescribed $657 on 3-mo).
Plan ladder: Monthly $249/mo, 3-mo $219/mo, 6-mo $199/mo, 12-mo $179/mo.
Plan ladder: Monthly $329/mo, 3-mo $309/mo, 6-mo $289/mo, 12-mo $269/mo (Total if prescribed $927 on 3-mo).
Plan ladder: Monthly $349/mo, 3-mo $299/mo, 6-mo $289/mo, 12-mo $269/mo (Total if prescribed $897 on 3-mo).
Monthly plan only ($1,069/mo).
Monthly plan only ($1,299/mo).
Monthly plan only ($1,349/mo).
Trimi Health
Billed monthly. Flat price at every dose.
Quarterly plan: billed $435 every 3 months.
Bi-annual plan: billed $720 every 6 months.
Annual plan: billed $1,188 yearly upfront (or BNPL via Affirm/Klarna/Afterpay). This is the advertised headline price.
Billed monthly. Flat price at every dose.
Quarterly plan: billed $597 every 3 months.
6-month plan: billed $1,050 every 6 months.
Annual plan: billed $1,500 yearly upfront (or BNPL). This is the advertised headline price.
What’s included
RxSpan MD
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
Trimi Health
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
RxSpan MD
6.8/10
Trimi Health
9.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | RxSpan MD | Trimi Health |
|---|---|---|
| Starting Price | $249/mo | ✓$99/mo |
| Features | ✓7 features | 3 features |
| States Available | 50 | 50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About RxSpan MD
RxSpan MD prices compounded semaglutide and tirzepatide from $249/mo, as injections or oral capsules, and also carries brand-name Wegovy, Zepbound and Ozempic. It is unusually transparent for the category: it names its 503A pharmacy partners, Belmar, Strive, Epiq Scripts and Casa Pharma, and its medical group. Shipping is free and unlimited 24/7 support is included. The physician-led practice was founded by Dr. John Diaz, a board-certified plastic surgeon, and is available in all 50 states.
Read our full RxSpan MD review →About Trimi Health
Trimi Health is a telehealth seller whose compounded GLP-1 pricing is among the lowest available.
Read our full Trimi Health review →Pros & Cons
RxSpan MD
What we like
- Semaglutide at $249 a month, within the normal band around this register's $189 median for the same drug and form
- The monthly figure covers medication, consult, shipping, coaching
- Coverage is published for all 50 states
- Names 4 dispensing pharmacies, which most sellers in this register do not do
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- No price appears until the medical intake is complete, so the cost cannot be compared before health information is submitted
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Trimi Health
What we like
- Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
- Tirzepatide at $125 a month, 53% below the $267 median for the same drug and form across this register
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
- The monthly figure covers medication, consult, shipping
- Coverage is published for all 50 states
- Names 2 dispensing pharmacies, which most sellers in this register do not do
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Trimi Health takes it, 9.4 against 6.8, and it is especially strong on knowing which pharmacy fills the vial — it names VialsRx. RxSpan MD is no weak second and may fit you better on knowing which pharmacy fills the vial — it names Belmar Pharmacy.
Choose RxSpan MD if…
You want knowing which pharmacy fills the vial — it names Belmar Pharmacy and an opening price near $249 a month.
Choose Trimi Health if…
You want knowing which pharmacy fills the vial — it names VialsRx and an opening price near $99 a month.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
Telos Rx
Starting below a standard dose, with microdose tiers
From $49/mo
Get started →MyDrHank
An oral route if you will not self-inject
From $25/mo
Get started →SkinnyRx
Starting below a standard dose, with microdose tiers
From $149.25/mo
Get started →RxSpan MD vs Trimi Health: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring RxSpan MD and Trimi Health head-to-heads in the same category.
- RxSpan MD vs Embody
- RxSpan MD vs He & She MD
- RxSpan MD vs Lean Meds
- Trimi Health vs NextMeds
- Trimi Health vs bmiMD
- Trimi Health vs CoreAge Rx
Or see the full category ranking.
Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.