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RxSpan MD vs Trimi Health

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
RxSpan MD logo

RxSpan MD

6.8
★★★☆☆3.4/5

Best for: knowing which pharmacy fills the vial — it names Belmar Pharmacy

Visit RxSpan MD
VS
Trimi Health logo

Trimi Health

9.4
★★★★4.7/5

Best for: knowing which pharmacy fills the vial — it names VialsRx

Visit Trimi Health

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, Trimi Health opens cheaper — $99/mo against $249, and Trimi Health finishes ahead, 9.4 to 6.8. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

RxSpan MD

Semaglutide InjectionCompounded
$249$194/mo
Save 22% right now
semaglutide

Plan ladder: Monthly $249/mo, 3-mo $219/mo, 6-mo $199/mo, 12-mo $194/mo. Card labeled '(For the first month)'; plan picker shows flat recurring rates (Total if prescribed $657 on 3-mo).

Semaglutide CapsulesCompounded
$249$179/mo
Save 28% right now
semaglutide

Plan ladder: Monthly $249/mo, 3-mo $219/mo, 6-mo $199/mo, 12-mo $179/mo.

Tirzepatide InjectionCompounded
$329$269/mo
Save 18% right now
tirzepatide

Plan ladder: Monthly $329/mo, 3-mo $309/mo, 6-mo $289/mo, 12-mo $269/mo (Total if prescribed $927 on 3-mo).

Tirzepatide CapsulesCompounded
$349$269/mo
Save 23% right now
tirzepatide

Plan ladder: Monthly $349/mo, 3-mo $299/mo, 6-mo $289/mo, 12-mo $269/mo (Total if prescribed $897 on 3-mo).

ZepboundBrand-name
$1069/mo
tirzepatide

Monthly plan only ($1,069/mo).

OzempicBrand-name
$1299/mo
semaglutide

Monthly plan only ($1,299/mo).

WegovyBrand-name
$1349/mo
semaglutide

Monthly plan only ($1,349/mo).

Trimi Health

All doses (flat)Compounded
$175/mo
semaglutide

Billed monthly. Flat price at every dose.

All doses (flat)Compounded
$145/mo
semaglutide

Quarterly plan: billed $435 every 3 months.

All doses (flat)Compounded
$120/mo
semaglutide

Bi-annual plan: billed $720 every 6 months.

All doses (flat)Compounded
$99/mo
semaglutide

Annual plan: billed $1,188 yearly upfront (or BNPL via Affirm/Klarna/Afterpay). This is the advertised headline price.

All doses (flat)Compounded
$235/mo
tirzepatide

Billed monthly. Flat price at every dose.

All doses (flat)Compounded
$199/mo
tirzepatide

Quarterly plan: billed $597 every 3 months.

All doses (flat)Compounded
$175/mo
tirzepatide

6-month plan: billed $1,050 every 6 months.

All doses (flat)Compounded
$125/mo
tirzepatide

Annual plan: billed $1,500 yearly upfront (or BNPL). This is the advertised headline price.

What’s included

RxSpan MD

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

In the price

Trimi Health

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

RxSpan MD

6.8/10

Overall

Trimi Health

9.4/10

Value25%

3.5A
vs
B
10.0

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

3.0A
vs
B
8.0

Trust & Safety15%

7.5A
vs
B
10.0

Accessibility10%

10.0A
vs
B
10.0

Support10%

8.5A
vs
B
7.0

Features & Coverage

FeatureRxSpan MDTrimi Health
Starting Price$249/mo$99/mo
Features7 features3 features
States Available5050
Compounded✓ Yes✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About RxSpan MD

RxSpan MD prices compounded semaglutide and tirzepatide from $249/mo, as injections or oral capsules, and also carries brand-name Wegovy, Zepbound and Ozempic. It is unusually transparent for the category: it names its 503A pharmacy partners, Belmar, Strive, Epiq Scripts and Casa Pharma, and its medical group. Shipping is free and unlimited 24/7 support is included. The physician-led practice was founded by Dr. John Diaz, a board-certified plastic surgeon, and is available in all 50 states.

Read our full RxSpan MD review →

About Trimi Health

Trimi Health is a telehealth seller whose compounded GLP-1 pricing is among the lowest available.

Read our full Trimi Health review →

Pros & Cons

RxSpan MD

What we like

  • Semaglutide at $249 a month, within the normal band around this register's $189 median for the same drug and form
  • The monthly figure covers medication, consult, shipping, coaching
  • Coverage is published for all 50 states
  • Names 4 dispensing pharmacies, which most sellers in this register do not do
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No price appears until the medical intake is complete, so the cost cannot be compared before health information is submitted
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Trimi Health

What we like

  • Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
  • Tirzepatide at $125 a month, 53% below the $267 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
  • The monthly figure covers medication, consult, shipping
  • Coverage is published for all 50 states
  • Names 2 dispensing pharmacies, which most sellers in this register do not do
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Trimi Health

Trimi Health takes it, 9.4 against 6.8, and it is especially strong on knowing which pharmacy fills the vial — it names VialsRx. RxSpan MD is no weak second and may fit you better on knowing which pharmacy fills the vial — it names Belmar Pharmacy.

Choose RxSpan MD if…

You want knowing which pharmacy fills the vial — it names Belmar Pharmacy and an opening price near $249 a month.

Choose Trimi Health if…

You want knowing which pharmacy fills the vial — it names VialsRx and an opening price near $99 a month.

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Starting below a standard dose, with microdose tiers

7.0

MyDrHank

An oral route if you will not self-inject

6.0

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Starting below a standard dose, with microdose tiers

RxSpan MD vs Trimi Health: FAQ

Glossary

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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.