GLP Watchdog

RxSpan MD vs SkinnyRx

SkinnyRx has an open FDA warning letter dated February 20, 2026. RxSpan MD has none. On brand-name tirzepatide pen, RxSpan MD costs $3,972 less a year at standing rates: $1,069 a month against $1,400 a month at SkinnyRx. It is one of two products the two sell at comparable terms.

To see where both sit among the other sellers, read our best weight-loss injection providers board.

By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed

The record

RxSpan MD / SkinnyRx

RxSpan MD logo

RxSpan MD

7.9/10

SkinnyRx logo

SkinnyRx

6.3/10

FDA warning letters
None on record
Pharmacy
None named in our record
Lowest standing price
$249/moCompounded semaglutide injection
$248/moBrand-name semaglutide pill
States
All 50 states
47 states
Checked
Prices captured Record checked October 2026
Prices captured Record checked October 2026
Visit RxSpan MD
Visit SkinnyRx

Both RxSpan MD and SkinnyRx are affiliate partners: we are paid if you sign up through our links. Neither is featured. Scores are computed the same way for both (RxSpan MD 7.9, SkinnyRx 6.3). How we are paid

What the record shows

  1. 01

    SkinnyRx has an open FDA warning letter dated February 20, 2026. RxSpan MD has none.

  2. 02

    RxSpan MD names four pharmacies. SkinnyRx names no compounding pharmacy in our record.

  3. 03

    On brand-name tirzepatide pen, RxSpan MD costs $3,972 less a year at standing rates: $1,069 a month against $1,400 a month at SkinnyRx. It is one of two products the two sell at comparable terms.

  4. 04

    Only SkinnyRx lists a price for compounded oral semaglutide, compounded oral tirzepatide and brand-name semaglutide pill.

  5. 05

    RxSpan MD covers three states SkinnyRx does not.

Prices and terms, product by product

A price is set against the other side only for the same product, and only when both are standing monthly or 4-week rates. Those pairs are compared by yearly cost.

RxSpan MD

SkinnyRx

Compounded semaglutide injection

$249/mo

$2,988 a year

$99/mo

first month only; not compared

Compounded tirzepatide injection

$329/mo

$3,948 a year

$99/mo

first month only; not compared

Brand-name semaglutide pen

$1,299/moLower

$15,588 a year

$1,400/mo

$16,800 a year

Brand-name tirzepatide pen

$1,069/moLower

$12,828 a year

$1,400/mo

$16,800 a year

Compounded oral semaglutide
Not sold or not priced

$149/mo

first month only; not compared

Compounded oral tirzepatide
Not sold or not priced

$199/mo

first month only; not compared

Brand-name semaglutide pill
Not sold or not priced

$248/mo

$2,976 a year

Foundayo (orforglipron) pill
Not sold or not priced

$248/mo

$2,976 a year

Price includes
Medication, clinician visits, shipping, coaching
Medication, clinician visits, shipping
Cancel any time
Yes, stated
Yes, stated
Minimum term
None
None stated; subscriptions auto-renew until canceled at least 5 days before the renewal date
Refunds
Not stated
Full refund before a provider completes the prescription review; no refunds for partially used subscription periods
Early-exit fee
None stated
Not stated

Read off each seller’s own pages. RxSpan MD: October 17, 2026. SkinnyRx: October 30, 2026. Every plan and dose we hold is on the full review.

The case for each

The case for RxSpan MD

7.9/10
  • No FDA warning letter on record
  • $1,212 a year less on brand-name semaglutide pen
  • $3,972 a year less on brand-name tirzepatide pen
  • Names its compounding pharmacy
Visit RxSpan MD

The case for SkinnyRx

6.3/10
  • Sells compounded oral semaglutide and compounded oral tirzepatide, which RxSpan MD does not price
  • Open FDA warning letter, February 20, 2026
  • Names no compounding pharmacy
Visit SkinnyRx

Scores

RxSpan MD 7.9 · SkinnyRx 6.3 out of 10. Six weighted parts.

Value25%

3.5A
vs
B
5.6

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
3.0

Trust & Safety15%

10.0A
vs
B
2.0

Accessibility10%

10.0A
vs
B
9.5

Support10%

8.5A
vs
B
7.0

The score is the same formula for every seller. Payment does not enter it. Method

RxSpan MD vs SkinnyRx: questions

SkinnyRx has an open FDA warning letter dated February 20, 2026. RxSpan MD has none. Letters are matched to a seller by company, domain and address, never by a similar name.
RxSpan MD names four pharmacies. SkinnyRx names no compounding pharmacy in our record. A 503A pharmacy compounds for named patients on a prescription; a 503B outsourcing facility is registered with FDA and inspected under federal manufacturing rules.
RxSpan MD, by $1,212 a year at standing rates. RxSpan MD: $1,299 a month, about $15,588 a year. SkinnyRx: $1,400 a month, about $16,800 a year.
RxSpan MD states you can cancel at any time. SkinnyRx states you can cancel at any time; refunds: full refund before a provider completes the prescription review; no refunds for partially used subscription periods.
Both RxSpan MD and SkinnyRx are affiliate partners: we are paid if you sign up through our links. Neither is featured. Scores are computed the same way for both (RxSpan MD 7.9, SkinnyRx 6.3).

Other sellers we are paid by

Affiliate partners outside this pair. Each has its own record and review, scored the same way.

Sellers closest to these two

Matched on molecule, form and price. Every pair we list · The register

Brand names on this page are registered marks. Novo Nordisk holds Wegovy®, Ozempic® and Rybelsus®; Eli Lilly holds Zepbound®, Mounjaro® and Foundayo®. Neither company has any tie to GLP Watchdog. Trademarks