Premium Health vs The Protocole

Premium Health has an open FDA warning letter dated February 20, 2026. The Protocole has none. On compounded tirzepatide injection, The Protocole costs $1,063 less a year at standing rates: $329 a month (billed every 4 weeks) against $445 a month at Premium Health. It is one of two products the two sell at comparable terms.

By Ruth Calder · Enforcement Editor

Editorially reviewed. Not medical advice · How we verify contentLast reviewed October 2026

The record

Premium Health / The Protocole

Premium Health

6.3/10

The Protocole

7.1/10

FDA warning letters

Open letter, February 20, 2026No. 721474

None on record

Pharmacy

None named in our record

Lowest standing price

$275/moCompounded semaglutide injection

$279/moCompounded semaglutide injection, billed every 4 weeks

States

No state list published

All 50 states

Checked

Prices captured October 17, 2026Record checked October 2026

Visit Premium Health Full review

Visit The Protocole Full review

Neither Premium Health nor The Protocole pays us. Links to them earn nothing. Scores: Premium Health 6.3, The Protocole 7.1. How we are paid

What the record shows

01
Premium Health has an open FDA warning letter dated February 20, 2026. The Protocole has none.
02
Premium Health names three pharmacies, all 503A. The Protocole names no compounding pharmacy in our record.
03
On compounded tirzepatide injection, The Protocole costs $1,063 less a year at standing rates: $329 a month (billed every 4 weeks) against $445 a month at Premium Health. It is one of two products the two sell at comparable terms.
04
The Protocole lists all 50 states. Premium Health publishes no state list.

Prices and terms, product by product

A price is set against the other side only for the same product, and only when both are standing monthly or 4-week rates. Those pairs are compared by yearly cost.

Premium Health

The Protocole

Compounded semaglutide injection

$275/moLower

$3,300 a year

$279/mo

$3,627 a year, 13 charges

Compounded tirzepatide injection

$445/mo

$5,340 a year

$329/moLower

$4,277 a year, 13 charges

Price includes

Medication, clinician visits, shipping

Medication

Cancel any time

Yes, stated

Minimum term

None (month to month)

No subscription. Each 4-week supply is a separate order; the terms say medication may be bought as needed

Refunds

Medication cost is not refundable

Money back in full for a declined applicant, or for a cancellation made before any clinical work starts; after that point, "all sales are final."

Early-exit fee

None stated

Not stated

Read off each seller’s own pages. Premium Health: October 17, 2026. The Protocole: October 17, 2026. Every plan and dose we hold is on the full review.

The case for each

The case for Premium Health

6.3/10

$327 a year less on compounded semaglutide injection
Names its compounding pharmacy

Open FDA warning letter, February 20, 2026
Publishes no state list

Visit Premium Health

The case for The Protocole

7.1/10

No FDA warning letter on record
$1,063 a year less on compounded tirzepatide injection

Names no compounding pharmacy

Visit The Protocole

Scores

Premium Health 6.3 · The Protocole 7.1 out of 10. Six weighted parts.

Value25%

2.7

3.0

Effectiveness25%

10.0

User Experience15%

7.5

8.0

Trust & Safety15%

5.0

7.5

Accessibility10%

5.0

10.0

Support10%

7.0

5.0

The score is the same formula for every seller. Payment does not enter it. Method

Premium Health vs The Protocole: questions

Premium Health has an open FDA warning letter dated February 20, 2026. The Protocole has none. Letters are matched to a seller by company, domain and address, never by a similar name.

Premium Health names three pharmacies, all 503A. The Protocole names no compounding pharmacy in our record. A 503A pharmacy compounds for named patients on a prescription; a 503B outsourcing facility is registered with FDA and inspected under federal manufacturing rules.

Premium Health, by $327 a year at standing rates. Premium Health: $275 a month, about $3,300 a year. The Protocole: $279 a month (billed every 4 weeks), about $3,627 a year.

Premium Health states you can cancel at any time; refunds: medication cost is not refundable. The Protocole states you can cancel at any time; refunds: money back in full for a declined applicant, or for a cancellation made before any clinical work starts; after that point, "all sales are final.".

Neither Premium Health nor The Protocole pays us. Links to them earn nothing. Scores: Premium Health 6.3, The Protocole 7.1.

Other sellers we are paid by

Affiliate partners outside this pair. Each has its own record and review, scored the same way.

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Matched on molecule, form and price. Every pair we list · The register