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PepHaūs vs Tuyo Health

PepHaūs costs $3 less a month, and both sell semaglutide and tirzepatide.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
PepHaūs logo

PepHaūs

8.3
★★★★☆4.2/5

Best for: coverage in all 50 states, which most sellers will not confirm

Visit PepHaūs →
VS

Tuyo Health

6.9
★★★★☆3.5/5

Best for: compounded semaglutide at $155/month

Visit Tuyo Health →

If you are choosing between PepHaūs and Tuyo Health, the first difference is cost: PepHaūs is $3 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. PepHaūs leads our six-part score, 8.3 to 6.9. One of the two has an FDA warning letter on record, covered below.

PepHaūs vs Tuyo Health price

PepHaūs is the cheaper way in: $152 a month against $155 a month at Tuyo Health. That is $3 less each month (2% lower), or about $36 over a year of treatment.

Drug by drug: Semaglutide is cheaper at PepHaūs ($152 a month vs $155 a month); tirzepatide is cheaper at PepHaūs ($246 a month vs $279 a month).

Medications and formats

Both sell semaglutide and tirzepatide.

On format they match: each offers compounded injections.

Where each one treats patients

PepHaūs lists 50 states, and Tuyo Health does not publish where it ships.

Pricing

PepHaūs

Compounded SemaglutideCompounded
$152/mo
semaglutide

From $152/mo on quarterly plan ($179/mo otherwise)

Compounded TirzepatideCompounded
$246/mo
tirzepatide

From $246/mo

Tuyo Health

All doses (flat)Compounded
$155/mo
semaglutide

All-inclusive: protocol, consults, shipping and periodic labs

All doses (flat)Compounded
$279/mo
tirzepatide

All-inclusive compounded plan; brand Zepbound also offered separately

What each price covers

Both prices cover the clinician visit, the medication itself and shipping.

PepHaūs is silent on lab work and coaching.

Tuyo Health is silent on lab work and coaching.

PepHaūs

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Tuyo Health

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall, PepHaūs scores 8.3 and Tuyo Health 6.9 out of 10.

PepHaūs is stronger on user experience (8.0 vs 7.5), trust & safety (8.5 vs 3.5) and accessibility (10.0 vs 5.0).

Value, effectiveness and support are within half a point.

How we score

PepHaūs

8.3/10

Overall

Tuyo Health

6.9/10

Value25%

6.4A
vs
B
6.3

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
7.5

Trust & Safety15%

8.5A
vs
B
3.5

Accessibility10%

10.0A
vs
B
5.0

Support10%

7.0A
vs
B
7.0

FDA warning letters

The FDA sent Tuyo Health a warning letter dated September 9, 2025 (letter 716502), and it is still open.

PepHaūs has no FDA warning letter on record with us.

Features & Coverage

FeaturePepHaūsTuyo Health
Starting Price✓$152/mo$155/mo
Features6 features6 features
States Available50Not disclosed
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA Warning Letters✓None1 letter

About PepHaūs

PepHaūs prices compounded semaglutide from $152/mo and tirzepatide from $246/mo, with an extra 15% off on quarterly plans. Its pitch is all-inclusive pricing: medication, medical visit and shipping bundled into one cost. US-licensed providers prescribe and 503A compounding pharmacies ship. The telehealth pharmacy also sells NAD+, sermorelin and glutathione alongside weight loss.

Read our full PepHaūs review →

About Tuyo Health

155 dollars monthly is where compounded semaglutide begins, 279 dollars where compounded tirzepatide does, and those figures are all-inclusive: lab work at intervals, medical consultations at no charge, shipping inside the same week for free, and a protocol built for you. Going brand-name costs more, roughly 399 to 499 dollars a month for Wegovy or Zepbound, on top of a 99 dollar membership, and insurance can pull that down. Dr. German Echeverry founded Tuyo Health. Reach support at 866-642-8054 or by email.

Read our full Tuyo Health review →

Pros & Cons

PepHaūs

What we like

  • Semaglutide costs $152 a month, 18% below the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $246 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication, clinician visits and shipping
  • Serves all 50 states
  • We found no FDA warning letters issued to PepHaūs

Watch-outs

  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Tuyo Health

What we like

  • Semaglutide costs $155 a month, 16% below the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $279 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price stays the same as your dose goes up
  • The monthly price includes the medication, clinician visits and shipping
  • Baseline bloodwork is required before a prescription

Watch-outs

  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • The FDA has issued Tuyo Health a warning letter. Read what it alleges: a letter flags a problem but does not by itself rule a seller out
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: PepHaūs

PepHaūs wins this one, 8.3 to 6.9, above all for coverage in all 50 states, which most sellers will not confirm. It also costs $3 less each month than Tuyo Health. Tuyo Health fits better if compounded semaglutide at $155/month is your priority.

Choose PepHaūs if…

You want coverage in all 50 states, which most sellers will not confirm and an opening price near $152 a month.

Choose Tuyo Health if…

You want compounded semaglutide at $155/month and an opening price near $155 a month.

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PepHaūs vs Tuyo Health: FAQ

PepHaūs. It starts at $152 a month; Tuyo Health starts at $155 a month, $3 more per month.
Yes, both sell semaglutide and tirzepatide.
PepHaūs lists 50 states; Tuyo Health does not publish where it ships. Confirm your state before paying.
Both include the clinician visit, the medication itself and shipping.
PepHaūs has none. Tuyo Health has an open FDA warning letter from September 9, 2025.
No. Neither PepHaūs nor Tuyo Health pays us anything.

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