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NextMeds vs Trimi Health

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
NextMeds logo

NextMeds

9.2
★★★★4.6/5

Best for: semaglutide at $79/month, 59% under the register median

Visit NextMeds
VS
Trimi Health logo

Trimi Health

9.4
★★★★4.7/5

Best for: knowing which pharmacy fills the vial — it names VialsRx

Visit Trimi Health

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, NextMeds opens cheaper — $79/mo against $99, and Trimi Health finishes ahead, 9.4 to 9.2. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

NextMeds

InjectableCompounded
$79/mo
semaglutide

Compounded Semaglutide Membership, drug included when prescribed, alongside telehealth visits, a care coach, a dietitian and shipping. $79 is the month-to-month rate read from the pricing section on 2026-08-14. The site headline reads 'from $49/mo': that is the 12-month prepaid term divided down, not a monthly price, and the ladder between them is 3-month $76, 6-month $73, 12-month $49. A summer promotion was running with a stated end of August 20, so $79 may itself be discounted.

InjectableCompounded
$109/mo
tirzepatide

Compounded Tirzepatide Membership, drug included when prescribed, alongside telehealth visits, a care coach, a dietitian and shipping. $109 is the month-to-month rate read from the pricing section on 2026-08-14. The advertised 'GLP-1 + GIP: $95' is the 12-month prepaid term divided down; the ladder is 3-month $105, 6-month $100, 12-month $95. A summer promotion was running with a stated end of August 20, so $109 may itself be discounted.

Trimi Health

All doses (flat)Compounded
$175/mo
semaglutide

Billed monthly. Flat price at every dose.

All doses (flat)Compounded
$145/mo
semaglutide

Quarterly plan: billed $435 every 3 months.

All doses (flat)Compounded
$120/mo
semaglutide

Bi-annual plan: billed $720 every 6 months.

All doses (flat)Compounded
$99/mo
semaglutide

Annual plan: billed $1,188 yearly upfront (or BNPL via Affirm/Klarna/Afterpay). This is the advertised headline price.

All doses (flat)Compounded
$235/mo
tirzepatide

Billed monthly. Flat price at every dose.

All doses (flat)Compounded
$199/mo
tirzepatide

Quarterly plan: billed $597 every 3 months.

All doses (flat)Compounded
$175/mo
tirzepatide

6-month plan: billed $1,050 every 6 months.

All doses (flat)Compounded
$125/mo
tirzepatide

Annual plan: billed $1,500 yearly upfront (or BNPL). This is the advertised headline price.

What’s included

NextMeds

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

In the price

Trimi Health

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

NextMeds

9.2/10

Overall

Trimi Health

9.4/10

Value25%

10.0A
vs
B
10.0

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.5A
vs
B
10.0

Accessibility10%

10.0A
vs
B
10.0

Support10%

8.5A
vs
B
7.0

Features & Coverage

FeatureNextMedsTrimi Health
Starting Price$79/mo$99/mo
Features8 features3 features
States Available5050
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About NextMeds

Membership is a single flat monthly charge, and inside it sit free shipping, a registered dietitian holding a license, a care coach working 1:1, telehealth visits and the drug itself where one is prescribed. Insurance is not billed. A free assessment online goes to a licensed provider, who adds a phone or video consult in states that demand one, then prescribes if it fits. Compounding pharmacies within the Next Meds network, all licensed, ship. Auto-renewal does not exist, cancellation is open, and all 50 states can order compounded tirzepatide and semaglutide.

Read our full NextMeds review →

About Trimi Health

Trimi Health is a telehealth seller whose compounded GLP-1 pricing is among the lowest available.

Read our full Trimi Health review →

Pros & Cons

NextMeds

What we like

  • Semaglutide at $79 a month, 58% below the $189 median for the same drug and form across this register
  • Tirzepatide at $109 a month, 59% below the $267 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
  • The monthly figure covers medication, consult, shipping, coaching
  • Coverage is published for all 50 states
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Trimi Health

What we like

  • Semaglutide at $99 a month, 48% below the $189 median for the same drug and form across this register
  • Tirzepatide at $125 a month, 53% below the $267 median for the same drug and form across this register
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
  • The monthly figure covers medication, consult, shipping
  • Coverage is published for all 50 states
  • Names 2 dispensing pharmacies, which most sellers in this register do not do
  • No FDA warning letter matched this operator when we searched our enforcement register

Watch-outs

  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Trimi Health

Trimi Health takes it, 9.4 against 9.2, and it is especially strong on knowing which pharmacy fills the vial — it names VialsRx. NextMeds is no weak second and may fit you better on semaglutide at $79/month, 59% under the register median.

Choose NextMeds if…

You want semaglutide at $79/month, 59% under the register median and an opening price near $79 a month.

Choose Trimi Health if…

You want knowing which pharmacy fills the vial — it names VialsRx and an opening price near $99 a month.

Ready to start? Vetted GLP-1 providers

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7.0

MyDrHank

An oral route if you will not self-inject

6.0

SkinnyRx

Starting below a standard dose, with microdose tiers

9.4

Trimi Health

Knowing which pharmacy fills the vial — it names VialsRx

NextMeds vs Trimi Health: FAQ

Glossary

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