Lean Meds vs Trellis Vitality
An in-depth comparison of two leading GLP-1 Providers
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more

Lean Meds
Best for: knowing which pharmacy fills the vial — it names Belmar Pharmacy
Visit Lean Meds →
Trellis Vitality
Best for: knowing which pharmacy fills the vial — it names VialsRX
Visit Trellis Vitality →Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, Lean Meds opens cheaper — $79/mo against $150, and Lean Meds finishes ahead, 9.3 to 8.5. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
Lean Meds
Standing month-to-month rate. The advertised $69 is the 12-month prepay tier; 3-month is $76 and 6-month is $73.
Standing month-to-month rate. Prepay tiers: $105 for 3 months, $100 for 6, $95 for 12.
Trellis Vitality
Per-month rate falls on longer plans: $150 monthly, $140 on 3 months, $133 on 6 months. All dosages cost the same.
Per-month rate falls on longer plans: $199 monthly, $189 on 3 months, $179 on 6 months. All dosages cost the same.
What’s included
Lean Meds
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Trellis Vitality
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Lean Meds
9.3/10
Trellis Vitality
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Lean Meds | Trellis Vitality |
|---|---|---|
| Starting Price | ✓$79/mo | $150/mo |
| Features | 7 features | 7 features |
| States Available | 50 | 50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About Lean Meds
Titrating up does not raise the rate, which is flat and monthly: $79 to start on compounded semaglutide, $109 on compounded tirzepatide, the telehealth visit and shipping absorbed into both. Clinicians come from the OpenLoop Health network. Trinity HealthCare Supply, LLC operates the service and puts names to its five dispensing pharmacies as well as to the physicians who prescribe.
Read our full Lean Meds review →About Trellis Vitality
$150 a month opens compounded semaglutide and $199 compounded tirzepatide, identical at every dose, with no consult fee or membership stacked on top. Scale weight is not the frame; body composition is, which is why biomarker panels taken at home, a re-test at 90 days, and muscle-sparing choices such as glycine formulations and tesamorelin come with the GLP-1s. Trellis does the coordinating only: VialsRX in Houston dispenses and the Arora Health provider network prescribes.
Read our full Trellis Vitality review →Pros & Cons
Lean Meds
What we like
- Semaglutide at $79 a month, 58% below the $189 median for the same drug and form across this register
- Tirzepatide at $109 a month, 59% below the $267 median for the same drug and form across this register
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
- The monthly figure covers medication, consult, shipping
- Coverage is published for all 50 states
- Names 5 dispensing pharmacies, which most sellers in this register do not do
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Trellis Vitality
What we like
- Semaglutide at $150 a month, within the normal band around this register's $189 median for the same drug and form
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
- The monthly figure covers medication, consult, shipping
- Coverage is published for all 50 states
- Names VialsRX as the dispensing pharmacy, which most sellers in this register do not do
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Lean Meds takes it, 9.3 against 8.5, and it is especially strong on knowing which pharmacy fills the vial — it names Belmar Pharmacy. Trellis Vitality is no weak second and may fit you better on knowing which pharmacy fills the vial — it names VialsRX.
Choose Lean Meds if…
You want knowing which pharmacy fills the vial — it names Belmar Pharmacy and an opening price near $79 a month.
Choose Trellis Vitality if…
You want knowing which pharmacy fills the vial — it names VialsRX and an opening price near $150 a month.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
Trimi Health
Knowing which pharmacy fills the vial — it names VialsRx
From $99/mo
Get started →Strut Health
Semaglutide at $99/month, 48% under the register median
From $99/mo
Get started →Oak
Semaglutide at $119/month, 37% under the register median
From $119/mo
Get started →Lean Meds vs Trellis Vitality: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Lean Meds and Trellis Vitality head-to-heads in the same category.
- Lean Meds vs Trimi Health
- Lean Meds vs Embody
- Lean Meds vs He & She MD
- Trellis Vitality vs NextMeds
- Trellis Vitality vs bmiMD
- Trellis Vitality vs CoreAge Rx
Or see the full category ranking.
Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.