GLP Watchdog

Enhance MD vs SkinnyRx

SkinnyRx has an open FDA warning letter dated February 20, 2026. Enhance MD has none. No price lines up like for like. They share compounded semaglutide injection, but SkinnyRx's $99 is a first-month price.

To see where both sit among the other sellers, read our best weight-loss injection providers board.

By Ruth Calder · Enforcement Editor
Editorially reviewed. Not medical advice · How we verify contentLast reviewed

The record

Enhance MD / SkinnyRx

Enhance MD logo

Enhance MD

7.5/10

Featured pick (affiliate partner)

SkinnyRx logo

SkinnyRx

6.3/10

FDA warning letters
None on record
Pharmacy
None named in our record
Lowest standing price
$249/moCompounded semaglutide injection, billed every 4 weeks
$248/moBrand-name semaglutide pill
States
40 states and DC
47 states
Checked
Prices captured Record checked October 2026
Prices captured Record checked October 2026
Visit Enhance MD
Visit SkinnyRx

SkinnyRx is our featured pick on this page because it is an affiliate partner: we are paid if you sign up through our link. Enhance MD pays us nothing. The scores are computed the same way for both and are shown as computed (Enhance MD 7.5, SkinnyRx 6.3). How we are paid

What the record shows

  1. 01

    SkinnyRx has an open FDA warning letter dated February 20, 2026. Enhance MD has none.

  2. 02

    Enhance MD names five pharmacies, all 503A. SkinnyRx names no compounding pharmacy in our record.

  3. 03

    No price lines up like for like. They share compounded semaglutide injection, but SkinnyRx's $99 is a first-month price.

  4. 04

    Only SkinnyRx lists a price for brand-name semaglutide pen, brand-name tirzepatide pen and compounded oral semaglutide.

  5. 05

    SkinnyRx covers seven states Enhance MD does not.

Prices and terms, product by product

A price is set against the other side only for the same product, and only when both are standing monthly or 4-week rates. Those pairs are compared by yearly cost.

Enhance MD

SkinnyRx

Compounded semaglutide injection

$249/mo

$3,237 a year, 13 charges

$99/mo

first month only; not compared

Compounded tirzepatide injection

$329/mo

$4,277 a year, 13 charges

$99/mo

first month only; not compared

Brand-name semaglutide pen
Not sold or not priced

$1,400/mo

$16,800 a year

Brand-name tirzepatide pen
Not sold or not priced

$1,400/mo

$16,800 a year

Compounded oral semaglutide
Not sold or not priced

$149/mo

first month only; not compared

Compounded oral tirzepatide
Not sold or not priced

$199/mo

first month only; not compared

Brand-name semaglutide pill
Not sold or not priced

$248/mo

$2,976 a year

Foundayo (orforglipron) pill
Not sold or not priced

$248/mo

$2,976 a year

Price includes
Medication, clinician visits, shipping, labs
Medication, clinician visits, shipping
Cancel any time
Yes, stated
Yes, stated
Minimum term
None month to month; longer plans charge once per 12, 24 or 48 weeks
None stated; subscriptions auto-renew until canceled at least 5 days before the renewal date
Refunds
Full refund of the initial payment if found ineligible during onboarding; no returns on prescription products
Full refund before a provider completes the prescription review; no refunds for partially used subscription periods

Read off each seller’s own pages. Enhance MD: October 17, 2026. SkinnyRx: October 30, 2026. Every plan and dose we hold is on the full review.

The case for each

The case for Enhance MD

7.5/10
  • No FDA warning letter on record
  • Names its compounding pharmacy
Visit Enhance MD

The case for SkinnyRx

6.3/10
Featured pick (affiliate partner)
  • Sells brand-name semaglutide pen and brand-name tirzepatide pen, which Enhance MD does not price
  • Lists 47 states against 40
  • Open FDA warning letter, February 20, 2026
  • Names no compounding pharmacy
Visit SkinnyRx

Scores

Enhance MD 7.5 · SkinnyRx 6.3 out of 10. Six weighted parts.

Value25%

3.5A
vs
B
5.6

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

7.0A
vs
B
3.0

Trust & Safety15%

9.0A
vs
B
2.0

Accessibility10%

8.4A
vs
B
9.5

Support10%

8.5A
vs
B
7.0

The score is the same formula for every seller. Payment does not enter it. Method

Enhance MD vs SkinnyRx: questions

SkinnyRx has an open FDA warning letter dated February 20, 2026. Enhance MD has none. Letters are matched to a seller by company, domain and address, never by a similar name.
Enhance MD names five pharmacies, all 503A. SkinnyRx names no compounding pharmacy in our record. A 503A pharmacy compounds for named patients on a prescription; a 503B outsourcing facility is registered with FDA and inspected under federal manufacturing rules.
No price lines up like for like. They share compounded semaglutide injection, but SkinnyRx's $99 is a first-month price. We only set two prices against each other when they are for the same product and both are standing month-to-month or 4-week rates.
Enhance MD states you can cancel at any time; refunds: full refund of the initial payment if found ineligible during onboarding; no returns on prescription products. SkinnyRx states you can cancel at any time; refunds: full refund before a provider completes the prescription review; no refunds for partially used subscription periods.
SkinnyRx is our featured pick on this page because it is an affiliate partner: we are paid if you sign up through our link. Enhance MD pays us nothing. The scores are computed the same way for both and are shown as computed (Enhance MD 7.5, SkinnyRx 6.3).

Other sellers we are paid by

Affiliate partners outside this pair. Each has its own record and review, scored the same way.

Sellers closest to these two

Matched on molecule, form and price. Every pair we list · The register

Brand names on this page are registered marks. Novo Nordisk holds Wegovy®, Ozempic® and Rybelsus®; Eli Lilly holds Zepbound®, Mounjaro® and Foundayo®. Neither company has any tie to GLP Watchdog. Trademarks