DudeMeds vs WeightlessRx
WeightlessRx costs $1 less a month, and both sell semaglutide and tirzepatide.
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WeightlessRx
Best for: coaching bundled into the price rather than sold separately
Visit WeightlessRx →If you are choosing between DudeMeds and WeightlessRx, the first difference is cost: WeightlessRx is $1 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. WeightlessRx leads our six-part score, 7.3 to 6.1.
DudeMeds vs WeightlessRx price
WeightlessRx is the cheaper way in: $174 a month against $175 a month on a prepaid plan at DudeMeds. That is $1 less each month (1% lower), or about $12 over a year of treatment.
DudeMeds' figure is a monthly average of a plan billed for several months at once, so the first charge is larger than the number shown.
Drug by drug: Semaglutide is cheaper at WeightlessRx ($174 a month vs $175 a month on a prepaid plan); tirzepatide is cheaper at DudeMeds ($233 a month vs $250 a month).
Medications and formats
Both sell semaglutide and tirzepatide.
On format, DudeMeds prices compounded injections and brand-name pens, while WeightlessRx prices compounded injections.
If you want the FDA-approved brand rather than a compounded version, DudeMeds is the only one of the two with a brand-name price.
Where each one treats patients
Neither DudeMeds nor WeightlessRx publishes the states it serves, so enter your state at the very start of each sign-up.
Pricing
DudeMeds
$175/mo (orig $295 struck), Total Billed $525 (Orig. $885); 503B compounded; cheapest product on site — advertised '$149+' price not found on any product page
$179/mo (orig $295), Total Billed $716 (Orig. $1,180)
$597 billed (orig $885); ongoing refill tier
$498 billed (orig $590); ongoing refill tier
$837 billed (orig $885); ongoing refill tier
$249/mo, billed as $747 up front (shown against a struck-through $1,299).
$699 billed (orig $1,299); ongoing refill tier — below the $249 tirz median
$598 billed (orig $866); ongoing refill tier
$1,179 billed (orig $1,299); NOTE site labels this 'High Dose' at 5mg/week — same mg as the low tier, likely a site labeling error
NEW branch: Total Billed $4,755 (3 months)
NEW branch: Total Billed $4,755 (3 months)
NEW branch: Total Billed $4,050 (3 months)
NEW branch: Total Billed $4,050 (3 months)
WeightlessRx
What each price covers
Both prices cover the clinician visit, the medication itself and shipping.
WeightlessRx's price also covers coaching, which DudeMeds does not claim.
DudeMeds is silent on lab work and coaching.
WeightlessRx is silent on lab work.
DudeMeds
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
WeightlessRx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
Where each one scores higher
Overall, WeightlessRx scores 7.3 and DudeMeds 6.1 out of 10.
WeightlessRx is stronger on user experience (7.5 vs 3.0), trust & safety (6.5 vs 4.0) and support (8.5 vs 7.0).
Value, effectiveness and accessibility are within half a point.
DudeMeds
6.1/10
WeightlessRx
7.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
FDA warning letters
Neither DudeMeds nor WeightlessRx has an FDA warning letter on record with us.
Features & Coverage
| Feature | DudeMeds | WeightlessRx |
|---|---|---|
| Starting Price | $175/mo prepaid | ✓$174/mo |
| Features | ✓4 features | 2 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warning Letters | None | None |
About DudeMeds
Semaglutide and tirzepatide start at $175/month, sold in injectable and oral formats alike, with free shipping, no doctor fee and no membership fee. DudeMeds is a telehealth platform for men that also sells hair loss, ED and TRT treatments, and it accepts clinic-switch patients who come from an existing GLP-1 and TRT provider.
Read our full DudeMeds review →About WeightlessRx
WeightlessRx sells compounded tirzepatide formulations, including versions with B12 added.
Read our full WeightlessRx review →Pros & Cons
DudeMeds
What we like
- Semaglutide costs $175 a month, close to the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $233 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
- The monthly price includes the medication, clinician visits and shipping
- We found no FDA warning letters issued to DudeMeds
Watch-outs
- You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
WeightlessRx
What we like
- Semaglutide costs $174 a month, close to the $185 median for compounded semaglutide across the sellers we compare
- Tirzepatide costs $250 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
- Shows its price before the medical questionnaire, so you can compare it without handing over health information
- The monthly price includes the medication, clinician visits, shipping and coaching
- We found no FDA warning letters issued to WeightlessRx
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
Watch-outs
- Confirm it serves your state before you start the intake
- Ask which pharmacy fills the prescription before you pay, so you can check its license
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
DudeMeds is where we would start, above all for compounded semaglutide at $175/month. WeightlessRx undercuts it by $1 a month, so if the monthly bill is what decides it, WeightlessRx is the pick. WeightlessRx fits better if coaching bundled into the price rather than sold separately is your priority.
Choose DudeMeds if…
You want compounded semaglutide at $175/month and an opening price near $175 a month.
Choose WeightlessRx if…
You want coaching bundled into the price rather than sold separately and an opening price near $174 a month.
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RxSpan MD
Knowing which pharmacy fills the vial: it names Belmar Pharmacy
From $249/mo
Get started →Luvo Health
Moving between compounded and brand without changing seller
From $249/mo
Get started →Strut Health
Semaglutide at $99/month, 48% below the typical price
From $99/mo
Get started →DudeMeds vs WeightlessRx: FAQ
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