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Blue Sky MD vs Effecty

Blue Sky MD and Effecty both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
Blue Sky MD logo

Blue Sky MD

6.6
★★★☆☆3.3/5

Best for: coaching bundled into the price rather than sold separately

Visit Blue Sky MD →
VS
Effecty logo

Effecty

8.2
★★★★☆4.1/5

Best for: moving between compounded and brand without changing seller

Visit Effecty →

If you are choosing between Blue Sky MD and Effecty, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Effecty leads our six-part score, 8.2 to 6.6.

Blue Sky MD vs Effecty price

Blue Sky MD and Effecty start at the same figure, $160 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.

Drug by drug: Semaglutide costs the same at both, $160 a month; tirzepatide costs the same at both, $240 a month.

Medications and formats

Both sell semaglutide and tirzepatide.

On format, Blue Sky MD prices compounded injections, while Effecty prices compounded injections and brand-name pens.

If you want the FDA-approved brand rather than a compounded version, Effecty is the only one of the two with a brand-name price.

Where each one treats patients

Blue Sky MD lists 1 state, and Effecty lists 50 states.

They overlap in 1 state. Effecty alone covers 49 states, including Alaska, Alabama, Arkansas and Arizona.

Pricing

Blue Sky MD

Starting doseCompounded
$160/mo
semaglutide

Compounded semaglutide as low as $40/week in-office ($40 × 4 weeks = $160 a month). Dispensed in-office or shipped to your home.

Starting doseCompounded
$240/mo
tirzepatide

Compounded tirzepatide at $60/week in-office ($60 × 4 weeks = $240 a month). Dispensed in-office or shipped to your home.

Effecty

Compounded GLP-1 (12-mo plan)Compounded
$160$60/mo
Save 63% right now
semaglutide

$60 first month, then $160/mo on the 12-month plan.

Compounded GLP-1 (1-mo)Compounded
$205$105/mo
Save 49% right now
semaglutide

$105 first month, then $205/mo.

Compounded GLP-1+GIP (tirzepatide-class, 12-mo plan)Compounded
$240$140/mo
Save 42% right now
tirzepatide

NEW tirzepatide-class dual-agonist line. $140 first month, then $240/mo on the 12-month plan.

Compounded GLP-1+GIP (tirzepatide-class, 1-mo)Compounded
$305$205/mo
Save 33% right now
tirzepatide

$205 first month, then $305/mo.

OzempicBrand-name
$1300/mo
semaglutide
WegovyBrand-name
$1600/mo
semaglutide
ZepboundBrand-name
$1400/mo
tirzepatide
MounjaroBrand-name
$1300/mo
tirzepatide

What each price covers

Both prices cover the clinician visit, the medication itself and shipping.

Blue Sky MD's price also covers coaching, which Effecty does not claim.

Effecty is silent on lab work and coaching.

Blue Sky MD

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Charged on top

Coaching

In the price

Effecty

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall, Effecty scores 8.2 and Blue Sky MD 6.6 out of 10.

Blue Sky MD is stronger on support (8.5 vs 7.0).

Effecty is stronger on value (6.0 vs 3.0), trust & safety (8.5 vs 7.5) and accessibility (10.0 vs 2.2).

Effectiveness and user experience are within half a point.

How we score

Blue Sky MD

6.6/10

Overall

Effecty

8.2/10

Value25%

3.0A
vs
B
6.0

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

7.5A
vs
B
8.5

Accessibility10%

2.2A
vs
B
10.0

Support10%

8.5A
vs
B
7.0

FDA warning letters

Neither Blue Sky MD nor Effecty has an FDA warning letter on record with us.

Features & Coverage

FeatureBlue Sky MDEffecty
Starting Price$160/mo$160/mo
Features✓8 features7 features
States Available1✓50
Compounded✓ Yes✓ Yes
Brand Name—✓ Yes
FSA/HSA Accepted——
FDA Warning LettersNoneNone

About Blue Sky MD

Compounded semaglutide starts at $40/week and compounded tirzepatide at $60/week, dispensed to patients' homes within 3-5 business days. Medication is not sold on its own: access requires enrollment in the full medical weight-loss program, which adds 1-on-1 wellness coaching, a nutrition tracking app, hormone analysis and a personalized plan under physician supervision. Blue Sky MD was founded in 2008, is LegitScript certified, and runs seven North Carolina clinics alongside telehealth visits.

Read our full Blue Sky MD review →

About Effecty

Compounded GLP-1 injections cost $160-$205/mo at Effecty, which also carries the brand-name drugs Mounjaro, Zepbound, Wegovy and Ozempic. There are no membership fees, shipping reaches all states nationwide, and the platform is LegitScript certified.

Read our full Effecty review →

Pros & Cons

Blue Sky MD

What we like

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication, clinician visits, shipping and coaching
  • We found no FDA warning letters issued to Blue Sky MD

Watch-outs

  • Not included in the monthly price: lab work
  • Serves only 1 states, so check that yours is one of them
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Effecty

What we like

  • Semaglutide costs $160 a month, 14% below the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $240 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price stays the same as your dose goes up
  • The monthly price includes the medication, clinician visits and shipping
  • Serves all 50 states
  • We found no FDA warning letters issued to Effecty

Watch-outs

  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Effecty

Effecty wins this one, 8.2 to 6.6, above all for moving between compounded and brand without changing seller. Blue Sky MD fits better if coaching bundled into the price rather than sold separately is your priority.

Choose Blue Sky MD if…

You want coaching bundled into the price rather than sold separately and an opening price near $160 a month.

Choose Effecty if…

You want moving between compounded and brand without changing seller and an opening price near $160 a month.

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Blue Sky MD vs Effecty: FAQ

Neither on the entry price: Blue Sky MD and Effecty both start at about $160 a month. The difference is in what the price includes.
Yes, both sell semaglutide and tirzepatide.
Effecty: 50 states against 1, with 1 in common.
Both include the clinician visit, the medication itself and shipping. Only Blue Sky MD includes coaching.
Blue Sky MD has none. Effecty has none.
No. Neither Blue Sky MD nor Effecty pays us anything.

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Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.