1st Optimal vs Superpower
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: coaching bundled into the price rather than sold separately
Visit 1st Optimal →
Superpower
Best for: bloodwork inside the monthly price rather than billed on top
Visit Superpower →Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, Superpower starts at $199/mo, and Superpower finishes ahead, 6.5 to 3.9. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
1st Optimal
Pricing not publicly listed.
Superpower
Marketing 'from' price on superpower.com/semaglutide; the standalone Marketplace product listing for the same compounded semaglutide shows $229/mo. Separate from the $199/year membership fee.
Brand Ozempic 'from' price shown alongside the compounded option on the same page; same bimonthly upfront-billing cadence applies.
What’s included
1st Optimal
Covered by the monthly price
Medication
Not stated
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
Superpower
Covered by the monthly price
Medication
In the price
Clinician visits
Not stated
Shipping
Not stated
Lab work
In the price
Coaching
Not stated
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
3.9/10
Superpower
6.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Superpower |
|---|---|---|
| Starting Price | — | $199/mo |
| Features | ✓8 features | 7 features |
| States Available | Not disclosed | 42 |
| Compounded | — | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About 1st Optimal
Neither a monthly price nor a list of states is published. 1st Optimal operates out of Michigan across telehealth and functional medicine, writing the GLP-1s semaglutide and tirzepatide either as a weekly injection or as a daily oral tablet. Around the prescription it stacks at-home lab testing, interpretation of the blood work, coaching without limit and protocols built individually, all framed as long-term weight loss and longevity. Credentialed providers work virtually, treatment goes to the home, and nothing binds you to a long contract.
Read our full 1st Optimal review →About Superpower
A health membership priced at $199 per year, built around 100+ biomarker lab tests taken twice a year rather than around selling GLP-1s. Members judged clinically appropriate can add prescription treatments, compounded semaglutide or brand-name Ozempic among them, through the in-house Marketplace, billed apart from the membership fee. Three fulfillment pharmacies are named: Strive Pharmacy, Belmar Pharmacy and Progress Pharmacy.
Read our full Superpower review →Pros & Cons
1st Optimal
What we like
- The monthly figure covers consult, shipping, coaching
- No FDA warning letter matched this operator when we searched our enforcement register
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
- Baseline bloodwork is required before a prescription
Watch-outs
- No price appears until the medical intake is complete, so the cost cannot be compared before health information is submitted
- No state list is on record here, so whether it serves your state cannot be confirmed from this page
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
Superpower
What we like
- Semaglutide at $1799 a month, within the normal band around this register's $1299 median for the same drug and form
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly figure covers medication and labs
- Coverage is published for 42 states
- No FDA warning letter matched this operator when we searched our enforcement register
- Baseline bloodwork is required before a prescription
Watch-outs
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide is compounded rather than FDA-approved, so it has not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Superpower takes it, 6.5 against 3.9, and it is especially strong on bloodwork inside the monthly price rather than billed on top. 1st Optimal is no weak second and may fit you better on coaching bundled into the price rather than sold separately.
Choose 1st Optimal if…
You want coaching bundled into the price rather than sold separately.
Choose Superpower if…
You want bloodwork inside the monthly price rather than billed on top and an opening price near $199 a month.
Ready to start? Vetted GLP-1 providers
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Oak
Semaglutide at $119/month, 37% under the register median
From $119/mo
Get started →Found
Tirzepatide at $169/month, 37% under the register median
From $99/mo
Get started →Telos Rx
Starting below a standard dose, with microdose tiers
From $49/mo
Get started →1st Optimal vs Superpower: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.