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1st Optimal vs MyDrHank

An in-depth comparison of two leading GLP-1 Providers

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By Ruth Calder · Enforcement Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

3.9
★★☆☆☆2/5

Best for: coaching bundled into the price rather than sold separately

Visit 1st Optimal
VS
MyDrHank logo

MyDrHank

7.0
★★★3.5/5

Best for: an oral route if you will not self-inject

Visit MyDrHank

Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, MyDrHank starts at $25/mo, and MyDrHank finishes ahead, 7.0 to 3.9. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.

Pricing

1st Optimal

Pricing not publicly listed.

MyDrHank

Generic Sildenafil — 1-Month planCompounded · oral
$35/mo
sildenafil

Unchanged vs entry. Tiers: 6-Month $150 total/$25 per mo; 3-Month $90/$30; 1-Month $35. mg strength still not disclosed pre-purchase.

Generic Sildenafil — 6-Month plan ($150 total)Compounded · oral
$25/mo
sildenafil

Unchanged.

Generic Tadalafil — 1-Month planCompounded · oral
$45/mo
tadalafil

Unchanged. Tiers: 6-Month $180/$30; 3-Month $105/$35; 1-Month $45.

Generic Tadalafil — 6-Month plan ($180 total)Compounded · oral
$30/mo
tadalafil

Unchanged.

Daily Tadalafil — 1-Month planCompounded · oral
$49/mo
tadalafil (low-dose daily)

Unchanged. Tiers: 6-Month $210/$35; 3-Month $120/$40; 1-Month $49.

Daily Tadalafil — 6-Month plan ($210 total)Compounded · oral
$35/mo
tadalafil (low-dose daily)

Unchanged.

MDH Drive — 1-Month planCompounded
$59/mo
sildenafil + tadalafil

Unchanged. Tiers: 6-Month $270/$45; 3-Month $150/$50; 1-Month $59.

MDH Drive — 6-Month plan ($270 total)Compounded
$45/mo
sildenafil + tadalafil

Unchanged.

Oral Semaglutide — Monthly planCompounded · oral
$249/mo
semaglutide (oral)

NEW itemized tiers: Monthly $249; Quarterly $635/$212; 6-Month $1,143/$190; Yearly $2,057/$171. A 'Semaglutide Tablets' page variant lists Monthly total $399/perMonth $329 (site-side inconsistency), Yearly $3,297/$275.

Oral Semaglutide — Yearly plan ($2,057 total)Compounded · oral
$171/mo
semaglutide (oral)

Matches site-wide 'Plans start at $171/mo for compounded semaglutide' disclaimer.

Compounded Semaglutide — Monthly planCompounded
$259/mo
semaglutide

Tiers: Monthly $259; Quarterly $660/$220; 6-Month $1,189/$198; Yearly $2,140/$178. Above the $175 sema median unless a long commitment is taken.

Compounded Semaglutide — Yearly plan ($2,140 total)Compounded
$178/mo
semaglutide
Compounded Tirzepatide — Monthly planCompounded
$349/mo
tirzepatide

Tiers: Monthly $349; Quarterly $890/$297; 6-Month $1,602/$267; Yearly $2,883/$240. Above the $249 tirz median month-to-month; only the yearly commit dips below. Their own disclaimer claims 'start at $200/mo for compounded tirzepatide' — no $200 tier exists on any card (internal inconsistency).

Compounded Tirzepatide — Yearly plan ($2,883 total)Compounded
$240/mo
tirzepatide

What’s included

1st Optimal

Covered by the monthly price

Medication

Not stated

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

In the price

MyDrHank

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

3.9/10

Overall

MyDrHank

7.0/10

Value25%

3.0A
vs
B
5.8

Effectiveness25%

5.0A
vs
B
10.0

User Experience15%

2.0A
vs
B
8.0

Trust & Safety15%

4.0A
vs
B
5.5

Accessibility10%

5.0A
vs
B
5.0

Support10%

5.0A
vs
B
5.0

Features & Coverage

Feature1st OptimalMyDrHank
Starting Price$25/mo
Features8 features4 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

Neither a monthly price nor a list of states is published. 1st Optimal operates out of Michigan across telehealth and functional medicine, writing the GLP-1s semaglutide and tirzepatide either as a weekly injection or as a daily oral tablet. Around the prescription it stacks at-home lab testing, interpretation of the blood work, coaching without limit and protocols built individually, all framed as long-term weight loss and longevity. Credentialed providers work virtually, treatment goes to the home, and nothing binds you to a long contract.

Read our full 1st Optimal review →

About MyDrHank

This entry covers the erectile-dysfunction side of MyDrHank, whose legal name is Dr. Hank, LLC. Four products sit on the list: sildenafil in generic form, tadalafil both generic and daily, and MDH Drive, which dissolves rapidly and pairs sildenafil with tadalafil. Every case gets reviewed online by providers holding U.S. licenses, and three partner pharmacies are named. Plans are itemized at one, three and six months, the cheapest being $25/mo for generic sildenafil, with free shipping and nothing to commit to.

Read our full MyDrHank review →

Pros & Cons

1st Optimal

What we like

  • The monthly figure covers consult, shipping, coaching
  • No FDA warning letter matched this operator when we searched our enforcement register
  • A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
  • Baseline bloodwork is required before a prescription

Watch-outs

  • No price appears until the medical intake is complete, so the cost cannot be compared before health information is submitted
  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here

MyDrHank

What we like

  • Semaglutide at $171 a month, within the normal band around this register's $199 median for the same drug and form
  • Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
  • No FDA warning letter matched this operator when we searched our enforcement register
  • Both oral and injectable options are on record, so the format is a choice rather than a condition

Watch-outs

  • No state list is on record here, so whether it serves your state cannot be confirmed from this page
  • No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: MyDrHank

MyDrHank takes it, 7.0 against 3.9, and it is especially strong on an oral route if you will not self-inject. 1st Optimal is no weak second and may fit you better on coaching bundled into the price rather than sold separately.

Choose 1st Optimal if…

You want coaching bundled into the price rather than sold separately.

Choose MyDrHank if…

You want an oral route if you will not self-inject and an opening price near $25 a month.

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7.9

Oak

Semaglutide at $119/month, 37% under the register median

8.8

Found

Tirzepatide at $169/month, 37% under the register median

8.3

Telos Rx

Starting below a standard dose, with microdose tiers

1st Optimal vs MyDrHank: FAQ

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