1st Optimal vs Breeze Meds
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: coaching bundled into the price rather than sold separately
Visit 1st Optimal →
Breeze Meds
Best for: knowing which pharmacy fills the vial — it names Belmar Pharmacy
Visit Breeze Meds →Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, Breeze Meds starts at $199/mo, and Breeze Meds finishes ahead, 7.7 to 3.9. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
1st Optimal
Pricing not publicly listed.
Breeze Meds
Displayed on rendered homepage card 'GLP-1 Injection / Starting at $199'. Checkout catalog JS shows monthly:199 with oldPrice:249 and bundles threeMonthly:748 / sixMonthly:1248 / yearly:2298 ($191.50/mo effective).
Homepage card displays 'Starting at $399'. The site's own checkout catalog (/_nuxt/tdPmVDYT.js) prices it monthly:299 with oldPrice:399 (bundles 1068/3mo, 1918/6mo, 3498/yr) — but checkout is intake-gated, so $299 was found in code, not rendered publicly; keep $399 as the published price and treat $299 as an unconfirmed in-checkout promo.
Rendered card 'Oral Semaglutide / Starting at $299 / One dissolvable tablet per day.' Catalog bundles: 899/3mo, 1799/6mo, 3498/yr.
Rendered card 'Oral Tirzepatide / Starting at $399 / One dissolvable tablet per day.' Catalog bundles: 1199/3mo, 2399/6mo, 4799/yr.
What’s included
1st Optimal
Covered by the monthly price
Medication
Not stated
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
Breeze Meds
Covered by the monthly price
Medication
In the price
Clinician visits
Not stated
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
3.9/10
Breeze Meds
7.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Breeze Meds |
|---|---|---|
| Starting Price | — | $199/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
Neither a monthly price nor a list of states is published. 1st Optimal operates out of Michigan across telehealth and functional medicine, writing the GLP-1s semaglutide and tirzepatide either as a weekly injection or as a daily oral tablet. Around the prescription it stacks at-home lab testing, interpretation of the blood work, coaching without limit and protocols built individually, all framed as long-term weight loss and longevity. Credentialed providers work virtually, treatment goes to the home, and nothing binds you to a long contract.
Read our full 1st Optimal review →About Breeze Meds
Breeze Meds is a Georgia-based telehealth seller shipping to all 50 states, with compounded semaglutide at $199/mo, tirzepatide at $399/mo, and NAD+ at $169/mo. It is LegitScript certified, names its medical team (Dr. Ana Lisa Carr MD and Dr. Kelly Tenbrink MD), and works through a 4-pharmacy compounding network via Lion MD: Belmar, Strive, Epiq Scripts, and Casa Pharma Rx.
Read our full Breeze Meds review →Pros & Cons
1st Optimal
What we like
- The monthly figure covers consult, shipping, coaching
- No FDA warning letter matched this operator when we searched our enforcement register
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
- Baseline bloodwork is required before a prescription
Watch-outs
- No price appears until the medical intake is complete, so the cost cannot be compared before health information is submitted
- No state list is on record here, so whether it serves your state cannot be confirmed from this page
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
Breeze Meds
What we like
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly figure covers medication and shipping
- Coverage is published for all 50 states
- Names 4 dispensing pharmacies, which most sellers in this register do not do
- No FDA warning letter matched this operator when we searched our enforcement register
- Both oral and injectable options are on record, so the format is a choice rather than a condition
Watch-outs
- Tirzepatide at $399 a month, 49% above the $267 register median for the same drug and form
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Breeze Meds takes it, 7.7 against 3.9, and it is especially strong on knowing which pharmacy fills the vial — it names Belmar Pharmacy. 1st Optimal is no weak second and may fit you better on coaching bundled into the price rather than sold separately.
Choose 1st Optimal if…
You want coaching bundled into the price rather than sold separately.
Choose Breeze Meds if…
You want knowing which pharmacy fills the vial — it names Belmar Pharmacy and an opening price near $199 a month.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
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Telos Rx
Starting below a standard dose, with microdose tiers
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An oral route if you will not self-inject
From $25/mo
Get started →SkinnyRx
Starting below a standard dose, with microdose tiers
From $149.25/mo
Get started →1st Optimal vs Breeze Meds: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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