1st Optimal vs Big Easy Weight Loss
An in-depth comparison of two leading GLP-1 Providers
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
1st Optimal
Best for: coaching bundled into the price rather than sold separately
Visit 1st Optimal →Big Easy Weight Loss
Best for: knowing which pharmacy fills the vial — it names Seven Cells
Visit Big Easy Weight Loss →Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, Big Easy Weight Loss starts at $133/mo, and Big Easy Weight Loss finishes ahead, 9.0 to 3.9. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
1st Optimal
Pricing not publicly listed.
Big Easy Weight Loss
Billed as 399 dollars per 12-week supply (new-patient price)
Billed as 499 dollars per 12-week supply (new-patient price)
What’s included
1st Optimal
Covered by the monthly price
Medication
Not stated
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
In the price
Big Easy Weight Loss
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
3.9/10
Big Easy Weight Loss
9.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Big Easy Weight Loss |
|---|---|---|
| Starting Price | — | $133/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 51 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
Neither a monthly price nor a list of states is published. 1st Optimal operates out of Michigan across telehealth and functional medicine, writing the GLP-1s semaglutide and tirzepatide either as a weekly injection or as a daily oral tablet. Around the prescription it stacks at-home lab testing, interpretation of the blood work, coaching without limit and protocols built individually, all framed as long-term weight loss and longevity. Credentialed providers work virtually, treatment goes to the home, and nothing binds you to a long contract.
Read our full 1st Optimal review →About Big Easy Weight Loss
Packages here span multiple weeks, not months. 399 dollars buys 12 weeks of compounded semaglutide, roughly 133 dollars per month, and 499 dollars buys the same span of compounded tirzepatide, roughly 166 dollars per month. An MD in New Orleans runs joinbigeasy.com, which ships across the country and states that all 50 states are served. Miller's, OptioRx, Hallandale and Seven Cells are the partner pharmacies named. Dr. Gabriel Lasala holds the Chief Medical Officer post; email and phone reach support.
Read our full Big Easy Weight Loss review →Pros & Cons
1st Optimal
What we like
- The monthly figure covers consult, shipping, coaching
- No FDA warning letter matched this operator when we searched our enforcement register
- A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake
- Baseline bloodwork is required before a prescription
Watch-outs
- No price appears until the medical intake is complete, so the cost cannot be compared before health information is submitted
- No state list is on record here, so whether it serves your state cannot be confirmed from this page
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
Big Easy Weight Loss
What we like
- Tirzepatide at $166 a month, 38% below the $267 median for the same drug and form across this register
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly price is recorded as flat across doses, so it does not climb as the dose is titrated up
- The monthly figure covers medication, consult, shipping
- Coverage is published for all 50 states
- Names 4 dispensing pharmacies, which most sellers in this register do not do
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Our Verdict
Big Easy Weight Loss takes it, 9.0 against 3.9, and it is especially strong on knowing which pharmacy fills the vial — it names Seven Cells. 1st Optimal is no weak second and may fit you better on coaching bundled into the price rather than sold separately.
Choose 1st Optimal if…
You want coaching bundled into the price rather than sold separately.
Choose Big Easy Weight Loss if…
You want knowing which pharmacy fills the vial — it names Seven Cells and an opening price near $133 a month.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
Trimi Health
Knowing which pharmacy fills the vial — it names VialsRx
From $99/mo
Get started →Strut Health
Semaglutide at $99/month, 48% under the register median
From $99/mo
Get started →Oak
Semaglutide at $119/month, 37% under the register median
From $119/mo
Get started →1st Optimal vs Big Easy Weight Loss: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring 1st Optimal and Big Easy Weight Loss head-to-heads in the same category.
- 1st Optimal vs Trimi Health
- 1st Optimal vs Embody
- 1st Optimal vs He & She MD
- Big Easy Weight Loss vs Lean Meds
- Big Easy Weight Loss vs NextMeds
- Big Easy Weight Loss vs bmiMD
Or see the full category ranking.
Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.