10rx vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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Amazon One Medical
Best for: oral orforglipron alongside the injectables
Visit Amazon One Medical →Two GLP-1 Providers chasing the same patients, trading off price, geography and what lands in the box differently. On our scoring, 10rx opens cheaper — $99.67/mo against $149, and 10rx finishes ahead, 8.1 to 7.1. What follows: the prices, what each plan actually covers, the six-dimension score, where each one is weak, and who should pick which.
Pricing
10rx
Compounded; GLP-1 options as low as under $100/mo
Compounded GLP-1 + GIP
Amazon One Medical
What’s included
10rx
Covered by the monthly price
Medication
In the price
Clinician visits
In the price
Shipping
In the price
Lab work
Not stated
Coaching
Not stated
Amazon One Medical
Covered by the monthly price
Medication
Charged on top
Clinician visits
In the price
Shipping
In the price
Lab work
Charged on top
Coaching
Not stated
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
8.1/10
Amazon One Medical
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | Amazon One Medical |
|---|---|---|
| Starting Price | ✓$99.67/mo | $149/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | — | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 10rx
10rx sets flat monthly rates on compounded GLP-1: semaglutide at $99.67, tirzepatide at $149.67, with NAD+ and sermorelin sold separately for energy and recovery. A free health quiz online reaches a board-certified telehealth doctor, who reads your history before writing anything, and licensed pharmacy partners handle discreet delivery. The company states it reaches every one of the 50 states. What it does not state is its operating company, its pharmacies, or any terms page.
Read our full 10rx review →About Amazon One Medical
Amazon runs its GLP-1 business through a single unified channel here. Prescribing sits with One Medical clinicians and covers three FDA-approved drugs, Foundayo, Zepbound, and Wegovy, with nothing compounded on the list. Fulfillment is Amazon Pharmacy: same-day delivery in roughly 3,000 US cities, or pickup kiosks at select One Medical locations. Membership beforehand is not a prerequisite, and cash pay and insurance are both accepted. Foundayo launched at $25/month for patients with insurance and the Lilly Savings Card, $149/month paying cash.
Read our full Amazon One Medical review →Pros & Cons
10rx
What we like
- Semaglutide at $99.67 a month, 47% below the $189 median for the same drug and form across this register
- Tirzepatide at $149.67 a month, 44% below the $267 median for the same drug and form across this register
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly figure covers medication, consult, shipping
- No FDA warning letter matched this operator when we searched our enforcement register
Watch-outs
- No state list is on record here, so whether it serves your state cannot be confirmed from this page
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
- Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality
Amazon One Medical
What we like
- Orforglipron at $149 a month, within the normal band around this register's $149 median for the same drug and form
- Publishes a price on its own site before the medical questionnaire, so it can be compared without handing over health information
- The monthly figure covers consult and shipping
- Coverage is published for all 50 states
- No FDA warning letter matched this operator when we searched our enforcement register
- Baseline bloodwork is required before a prescription
Watch-outs
- Billed separately from the monthly figure: medication, labs
- No dispensing pharmacy is named in our record, so its accreditation cannot be looked up from here
Our Verdict
10rx takes it, 8.1 against 7.1, and it is especially strong on semaglutide at $99.67/month, 47% under the register median. Amazon One Medical is no weak second and may fit you better on oral orforglipron alongside the injectables.
Choose 10rx if…
You want semaglutide at $99.67/month, 47% under the register median and an opening price near $99.67 a month.
Choose Amazon One Medical if…
You want oral orforglipron alongside the injectables and an opening price near $149 a month.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
Some of the links on this page earn us money. If you sign up with a provider after following one, that provider may pay GLP Watchdog a commission. Learn more
Gala
Moving between compounded and brand without changing seller
From $129/mo
Get started →Trimi Health
Knowing which pharmacy fills the vial — it names VialsRx
From $99/mo
Get started →Strut Health
Semaglutide at $99/month, 48% under the register median
From $99/mo
Get started →10rx vs Amazon One Medical: FAQ
Glossary
The words sellers use, defined. Tap any term.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.