From the FDA label (DailyMed)Verified 2026-07-12

Trulicity Storage & Handling

Where dulaglutide belongs and for how long: the cold range, the warm allowance, and what to do about a dose that froze or sat in the sun — read straight off the FDA prescribing information.

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Trulicity Storage at a Glance

Refrigerated (unopened)
36°F to 46°F (2°C to 8°C)
Room-temperature allowance
Up to 86°F (30°C) for a total of 14 days, then discard.
Freezing
Do not freeze TRULICITY. Do not use TRULICITY if it has been frozen.
Light
Store TRULICITY in its original carton to protect it from direct heat and light.

Source: Trulicity FDA prescribing information via DailyMed (SetID 463050bd-2b1c-40f5-b3c3-0a04bb433309), Section 16.2 How Supplied/Storage and Handling, read on 2026-07-12. Treat this as a summary: the full label and the patient instructions in your box are the authority.

Handling the pen or vial

Once you start using it: the in-use window is 14 days at room temperature. Write down the day you first used it — on the device itself or in your calendar — because the label says discard at the end of that window regardless of how much is left.

The carton it arrived in is the light protection, and the obvious place to write the first-use date, so keep the pen or vial inside it wherever you can. Between doses the needle comes off; a pen should never be stored with one attached.

Traveling with Trulicity

This one gives you the least room of any weekly pen in the class: 14 days out of the fridge, where its competitors allow three weeks to two months. On a trip, get it back into refrigeration at the first opportunity instead of assuming the margin you may be used to elsewhere.

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Frequently Asked Questions

An unopened Trulicity belongs in the fridge at 36°F to 46°F (2°C to 8°C). Up to 86°F (30°C) for a total of 14 days, then discard. Taken from the FDA label on DailyMed, SetID 463050bd-2b1c-40f5-b3c3-0a04bb433309, Section 16.2, read on 2026-07-12.
It survives, but on a clock. Up to 86°F (30°C) for a total of 14 days, then discard. Once that clock starts it does not stop: throw the product away after 14 days at room temperature, however much is left inside.
Do not freeze TRULICITY. Do not use TRULICITY if it has been frozen. Where you cannot be certain a dose stayed above freezing, treat it as unusable and ask your pharmacy for a replacement rather than risking it.
Store TRULICITY in its original carton to protect it from direct heat and light.