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NP2GO vs Trellis Vitality

NP2GO and Trellis Vitality both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
NP2GO logo

NP2GO

6.7
★★★☆☆3.4/5

Best for: compounded semaglutide at $150/month

Visit NP2GO →
VS
Trellis Vitality logo

Trellis Vitality

8.4
★★★★☆4.2/5

Best for: knowing which pharmacy fills the vial: it names VialsRX

Visit Trellis Vitality →

If you are choosing between NP2GO and Trellis Vitality, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Trellis Vitality leads our six-part score, 8.4 to 6.7.

NP2GO vs Trellis Vitality price

NP2GO and Trellis Vitality start at the same figure, $150 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.

Drug by drug: Semaglutide costs the same at both, $150 a month; tirzepatide is cheaper at Trellis Vitality ($199 a month vs $250 a month).

Medications and formats

Both sell semaglutide and tirzepatide.

On format they match: each offers compounded injections.

Where each one treats patients

NP2GO lists 40 states, and Trellis Vitality lists 50 states.

They overlap in 39 states. NP2GO alone covers District of Columbia. Trellis Vitality alone covers 11 states, including Alabama, Georgia, Indiana and Louisiana.

Pricing

NP2GO

0.25mg (Pay As You Go)Compounded
$150/mo
semaglutide
0.50mg (Pay As You Go)Compounded
$175/mo
semaglutide
1mg (Pay As You Go)Compounded
$235/mo
semaglutide
1.7mg (Pay As You Go)Compounded
$250/mo
semaglutide
2.5mg (Pay As You Go)Compounded
$350/mo
semaglutide
0.25-1mg (Month-to-Month Membership)Compounded
$199/mo
semaglutide
1.7-2.5mg (Month-to-Month Membership)Compounded
$299/mo
semaglutide
2.5mg (Pay As You Go)Compounded
$250/mo
tirzepatide
5mg (Pay As You Go)Compounded
$300/mo
tirzepatide
7.5mg (Pay As You Go)Compounded
$375/mo
tirzepatide
10mg (Pay As You Go)Compounded
$475/mo
tirzepatide
12.5mg (Pay As You Go)Compounded
$550/mo
tirzepatide
15mg (Pay As You Go)Compounded
$600/mo
tirzepatide
2.5-7.5mg (Month-to-Month Membership)Compounded
$299/mo
tirzepatide
10-15mg (Month-to-Month Membership)Compounded
$399/mo
tirzepatide

Trellis Vitality

Month-to-month, all dosages same priceCompounded
$150/mo
semaglutide

Per-month rate falls on longer plans: $150 monthly, $140 on 3 months, $133 on 6 months. All dosages cost the same.

Month-to-month, all dosages same priceCompounded
$199/mo
tirzepatide

Per-month rate falls on longer plans: $199 monthly, $189 on 3 months, $179 on 6 months. All dosages cost the same.

What each price covers

Trellis Vitality's price also covers the clinician visit, the medication itself and shipping, which NP2GO does not claim.

NP2GO does not say what its price includes.

Trellis Vitality is silent on lab work and coaching.

That matters most for the drug: unless NP2GO confirms otherwise, budget for medication on top of its listed price.

NP2GO

Inclusions not disclosed.

Trellis Vitality

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall, Trellis Vitality scores 8.4 and NP2GO 6.7 out of 10.

Trellis Vitality is stronger on user experience (8.0 vs 2.5), trust & safety (9.0 vs 6.0), accessibility (10.0 vs 8.4) and support (7.0 vs 5.0).

Value and effectiveness are within half a point.

How we score

NP2GO

6.7/10

Overall

Trellis Vitality

8.4/10

Value25%

6.5A
vs
B
6.6

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

2.5A
vs
B
8.0

Trust & Safety15%

6.0A
vs
B
9.0

Accessibility10%

8.4A
vs
B
10.0

Support10%

5.0A
vs
B
7.0

FDA warning letters

Neither NP2GO nor Trellis Vitality has an FDA warning letter on record with us.

Features & Coverage

FeatureNP2GOTrellis Vitality
Starting Price$150/mo$150/mo
Features✓8 features7 features
States Available40✓50
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted—✓ Yes
FDA Warning LettersNoneNone

About NP2GO

The full pricing matrix for compounded semaglutide and compounded tirzepatide is published openly, split two ways: Pay As You Go, billed per dose, where a visit fee of $99 falls every 3 months; or a flat membership month to month. Semaglutide enters at $150/mo. Nurse practitioners lead the operation, which runs a clinic in Edmond, Oklahoma alongside telehealth, dates to 2019, and belongs to the Obesity Medicine Association. Weight-loss visits by video cover 39 states and DC.

Read our full NP2GO review →

About Trellis Vitality

$150 a month opens compounded semaglutide and $199 compounded tirzepatide, identical at every dose, with no consult fee or membership stacked on top. Scale weight is not the frame; body composition is, which is why biomarker panels taken at home, a re-test at 90 days, and muscle-sparing choices such as glycine formulations and tesamorelin come with the GLP-1s. Trellis does the coordinating only: VialsRX in Houston dispenses and the Arora Health provider network prescribes.

Read our full Trellis Vitality review →

Pros & Cons

NP2GO

What we like

  • Semaglutide costs $150 a month, 19% below the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $250 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
  • Serves 40 states
  • We found no FDA warning letters issued to NP2GO
  • A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake

Watch-outs

  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Trellis Vitality

What we like

  • Semaglutide costs $150 a month, 19% below the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $199 a month, 20% below the $250 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price stays the same as your dose goes up
  • The monthly price includes the medication, clinician visits and shipping
  • Serves all 50 states
  • Names VialsRX as the pharmacy that fills its prescriptions, which most sellers do not
  • We found no FDA warning letters issued to Trellis Vitality

Watch-outs

  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Trellis Vitality

Trellis Vitality wins this one, 8.4 to 6.7, above all for knowing which pharmacy fills the vial: it names VialsRX. NP2GO fits better if compounded semaglutide at $150/month is your priority.

Choose NP2GO if…

You want compounded semaglutide at $150/month and an opening price near $150 a month.

Choose Trellis Vitality if…

You want knowing which pharmacy fills the vial: it names VialsRX and an opening price near $150 a month.

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NP2GO vs Trellis Vitality: FAQ

Neither on the entry price: NP2GO and Trellis Vitality both start at about $150 a month. The difference is in what the price includes.
Yes, both sell semaglutide and tirzepatide.
Trellis Vitality: 50 states against 40, with 39 in common.
Only Trellis Vitality includes the clinician visit, the medication itself and shipping.
NP2GO has none. Trellis Vitality has none.
No. Neither NP2GO nor Trellis Vitality pays us anything.

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