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Knownwell vs Rex MD

Knownwell and Rex MD both sell tirzepatide; this is how their prices, coverage and records differ.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
Knownwell logo

Knownwell

7.7
★★★★☆3.9/5

Best for: coverage in all 50 states, which most sellers will not confirm

Visit Knownwell →
VS
Rex MD logo

Rex MD

7.9
★★★★☆4/5

Best for: coverage in all 50 states, which most sellers will not confirm

Visit Rex MD →

If you are choosing between Knownwell and Rex MD, price alone will not settle it. Both prescribe tirzepatide, so moving from one to the other would not change your drug. Rex MD leads our six-part score, 7.9 to 7.7.

Knownwell vs Rex MD price

Knownwell and Rex MD start at the same figure, $349 a month, so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.

Drug by drug: Tirzepatide costs the same at both, $349 a month.

Medications and formats

Both sell tirzepatide.

On format they match: each offers brand-name pens.

Where each one treats patients

Knownwell lists 50 states, and Rex MD lists 50 states.

They overlap in 50 states.

Pricing

Knownwell

Zepbound self-pay (via LillyDirect)Brand-name
$349/mo
tirzepatide

Rex MD

Program subscriptionBrand-name
$199/mo
semaglutide
Zepbound vialBrand-name
$349/mo
tirzepatide

What each price covers

Rex MD's price also covers the clinician visit, the medication itself and shipping, which Knownwell does not claim.

Knownwell does not say what its price includes.

Rex MD is silent on lab work and coaching.

That matters most for the drug: unless Knownwell confirms otherwise, budget for medication on top of its listed price.

Knownwell

Inclusions not disclosed.

Rex MD

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall, Rex MD scores 7.9 and Knownwell 7.7 out of 10.

Rex MD is stronger on support (7.0 vs 5.0).

Value, effectiveness, user experience, trust & safety and accessibility are within half a point.

How we score

Knownwell

7.7/10

Overall

Rex MD

7.9/10

Value25%

10.0A
vs
B
10.0

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

3.0A
vs
B
3.0

Trust & Safety15%

5.0A
vs
B
5.0

Accessibility10%

10.0A
vs
B
10.0

Support10%

5.0A
vs
B
7.0

FDA warning letters

Neither Knownwell nor Rex MD has an FDA warning letter on record with us.

Features & Coverage

FeatureKnownwellRex MD
Starting Price$349/mo$349/mo
Features8 features8 features
States Available5050
Compounded——
Brand Name✓ Yes✓ Yes
FSA/HSA Accepted——
FDA Warning LettersNoneNone

About Knownwell

Copays fall as low as $25 where a patient is covered, and many insurance plans are taken. Knownwell calls itself weight-inclusive, combining metabolic with primary care; obesity-medicine specialist Dr. Angela Fitch co-founded it. Its drug list is branded: Wegovy, Zepbound, Ozempic, Saxenda, plus Foundayo, the GLP-1 taken by mouth. Virtual appointments run in all 50 states, with clinics in Boston, Chicago, Dallas-Fort Worth and Atlanta. It is a LillyDirect care provider and partners with Novo Nordisk on telehealth for the Wegovy pill. Dietitians and coaches work under physician oversight.

Read our full Knownwell review →

About Rex MD

The program is a flat monthly charge of about $199, which takes in the medical intake, consultations with a provider, the prescribed drug, syringes and overnight shipping at no cost; Zepbound vials start at around $349 per month. Rex MD belongs to LifeMD, aims at men's health, and runs its weight-management program 100 percent online, prescribing brand-name semaglutide and Zepbound (tirzepatide) vials that partner pharmacies fill. Its clinicians are US-based and licensed by state, LegitScript certifies the platform, all 50 states are served, and no insurance is billed.

Read our full Rex MD review →

Pros & Cons

Knownwell

What we like

  • Tirzepatide costs $349 a month, 72% below the $1249 median for brand-name tirzepatide across the sellers we compare
  • Serves all 50 states
  • We found no FDA warning letters issued to Knownwell

Watch-outs

  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Ask which pharmacy fills the prescription before you pay, so you can check its license

Rex MD

What we like

  • Semaglutide costs $199 a month, 80% below the $997 median for brand-name semaglutide across the sellers we compare
  • Tirzepatide costs $349 a month, 72% below the $1249 median for brand-name tirzepatide across the sellers we compare
  • The monthly price stays the same as your dose goes up
  • The monthly price includes the medication, clinician visits and shipping
  • Serves all 50 states
  • We found no FDA warning letters issued to Rex MD

Watch-outs

  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Ask which pharmacy fills the prescription before you pay, so you can check its license

Our Verdict

Winner: Rex MD

Rex MD wins this one, 7.9 to 7.7, above all for coverage in all 50 states, which most sellers will not confirm. Knownwell fits better if coverage in all 50 states, which most sellers will not confirm is your priority.

Choose Knownwell if…

You want coverage in all 50 states, which most sellers will not confirm and an opening price near $349 a month.

Choose Rex MD if…

You want coverage in all 50 states, which most sellers will not confirm and an opening price near $349 a month.

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Knownwell vs Rex MD: FAQ

Neither on the entry price: Knownwell and Rex MD both start at about $349 a month. The difference is in what the price includes.
Yes, both sell tirzepatide.
Both list 50 states and share 50.
Only Rex MD includes the clinician visit, the medication itself and shipping.
Knownwell has none. Rex MD has none.
No. Neither Knownwell nor Rex MD pays us anything.

Or see the full category ranking.

Novo Nordisk A/S owns the Wegovy®, Ozempic® and Rybelsus® marks; Eli Lilly and Company owns Mounjaro® and Zepbound®. Every other product name and mark on this page belongs to whoever owns it. No pharmaceutical manufacturer is affiliated with GLP Watchdog. See trademark disclaimer.