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Collective vs RxPepsDirect

Collective costs $5 less a month, and both sell semaglutide and tirzepatide.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed

Collective

8.4
★★★★☆4.2/5

Best for: flat any-dose pricing, if you can absorb a $199 annual membership on top

Visit Collective →
VS
RxPepsDirect logo

RxPepsDirect

5.8
★★★☆☆2.9/5

Best for: a published list of the 28 states it serves, when most sellers publish none

Visit RxPepsDirect →

If you are choosing between Collective and RxPepsDirect, the first difference is cost: Collective is $5 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Collective leads our six-part score, 8.4 to 5.8.

Collective vs RxPepsDirect price

Collective is the cheaper way in: $59 a month against $64 a month at RxPepsDirect. That is $5 less each month (8% lower), or about $60 over a year of treatment.

Drug by drug: Semaglutide is cheaper at Collective ($59 a month vs $64 a month); tirzepatide is cheaper at Collective ($69 a month vs $84 a month).

Medications and formats

Both sell semaglutide and tirzepatide.

On format they match: each offers compounded injections.

Where each one treats patients

Collective does not publish where it ships, and RxPepsDirect lists 28 states.

Pricing

Collective

Same price at any dose, month-to-monthCompounded
$59/mo
semaglutide

Homepage: "Compounded Semaglutide $59/mo. Same price, any dose." Excludes the required $199 annual membership.

Same price at any dose, month-to-monthCompounded
$69/mo
tirzepatide

Homepage pairs compounded tirzepatide with $69/mo on the same any-dose basis. Excludes the required $199 annual membership.

Required membership, $199/year (subscription, medication NOT included)Compounded
$199/mo
semaglutide

Collective's FAQ puts the cost at "$59/month + $199 annual membership." The membership is mandatory and is not in the headline price.

RxPepsDirect

StarterCompounded
$64/mo
semaglutide

From $25 per 1.2mg vial of semaglutide/B12, sold per vial rather than as a plan. At the 0.25mg/week starter dose (~1mg/month), one vial lasts about 5 weeks. First order: $25 vial + $39 visit fee = $64; each refill is another $39 visit plus the vial. $15 flat FedEx overnight shipping is extra. Higher doses need more vials a month. No labs or coaching included.

StarterCompounded
$84/mo
tirzepatide

From $45 per 12mg vial of tirzepatide/B12, sold per vial rather than as a plan. At the 2.5mg/week starter dose (10mg/month), one vial lasts about 5 weeks. First order: $45 vial + $39 visit fee = $84; each refill is another $39 visit plus the vial. $15 flat FedEx overnight shipping is extra. No labs or coaching included.

What each price covers

Both prices cover the clinician visit, the medication itself and shipping.

Collective is silent on lab work and coaching.

Collective

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

RxPepsDirect

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Charged on top

Coaching

Charged on top

Where each one scores higher

Overall, Collective scores 8.4 and RxPepsDirect 5.8 out of 10.

Collective is stronger on value (10.0 vs 3.0), user experience (8.0 vs 3.0) and trust & safety (6.5 vs 5.0).

RxPepsDirect is stronger on accessibility (6.5 vs 5.0).

Effectiveness and support are within half a point.

How we score

Collective

8.4/10

Overall

RxPepsDirect

5.8/10

Value25%

10.0A
vs
B
3.0

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
3.0

Trust & Safety15%

6.5A
vs
B
5.0

Accessibility10%

5.0A
vs
B
6.5

Support10%

7.0A
vs
B
7.0

FDA warning letters

Neither Collective nor RxPepsDirect has an FDA warning letter on record with us.

Features & Coverage

FeatureCollectiveRxPepsDirect
Starting Price✓$59/mo$64/mo
Features3 features✓8 features
States AvailableNot disclosed28
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA Warning LettersNoneNone

About Collective

Health For Everyone Inc., trading as CollectiveOS, sells compounded semaglutide at $59/mo and compounded tirzepatide at $69/mo on a membership model, with a mandatory $199 annual membership on top that the headline price does not include. It prices every dose the same, so the cost does not climb as the dose is titrated, and it does not require prepaying for medication. The site is marketed as being from the founder of Thrive Market. Neither its pharmacies nor its medical groups are named.

Read our full Collective review →

About RxPepsDirect

Pricing is per vial: semaglutide/B12 from $25/vial and tirzepatide/B12 from $45/vial, after a $39 asynchronous online medical visit, with no subscription required. Optimal Balance Pharmacy, a 503A in Texas, dispenses. Licensed NP/PA prescribers supervised by Medical Director Dr. Jonathan Snipes, MD issue patient-specific compounded prescriptions under the 503A pathway. FedEx overnight delivery, syringes and a travel case are included. Peptide RX LLC operates in 28 states and DC.

Read our full RxPepsDirect review →

Pros & Cons

Collective

What we like

  • Semaglutide costs $59 a month, 68% below the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $69 a month, 72% below the $250 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price stays the same as your dose goes up
  • The monthly price includes the medication, clinician visits and shipping
  • We found no FDA warning letters issued to Collective

Watch-outs

  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

RxPepsDirect

What we like

  • The monthly price includes the medication, clinician visits and shipping
  • We found no FDA warning letters issued to RxPepsDirect

Watch-outs

  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Not included in the monthly price: lab work, coaching
  • Serves only 28 states, so check that yours is one of them
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Collective

Collective wins this one, 8.4 to 5.8, above all for flat any-dose pricing, if you can absorb a $199 annual membership on top. It also costs $5 less each month than RxPepsDirect. RxPepsDirect fits better if a published list of the 28 states it serves, when most sellers publish none is your priority.

Choose Collective if…

You want flat any-dose pricing, if you can absorb a $199 annual membership on top and an opening price near $59 a month.

Choose RxPepsDirect if…

You want a published list of the 28 states it serves, when most sellers publish none and an opening price near $64 a month.

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6.6

Luvo Health

Moving between compounded and brand without changing seller

8.4

Strut Health

Semaglutide at $99/month, 48% below the typical price

8.4

Enhance MD

Knowing which pharmacy fills the vial: it names Tru Meds Rx

Collective vs RxPepsDirect: FAQ

Collective. It starts at $59 a month; RxPepsDirect starts at $64 a month, $5 more per month.
Yes, both sell semaglutide and tirzepatide.
Collective does not publish where it ships; RxPepsDirect lists 28 states. Confirm your state before paying.
Both include the clinician visit, the medication itself and shipping.
Collective has none. RxPepsDirect has none.
Collective pays us a commission on sign-ups through our links; RxPepsDirect does not. Scores are computed the same way for both.

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