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Ascend Medical vs MANÜ Telehealth

MANÜ Telehealth costs $2.29 less a month, and both sell semaglutide and tirzepatide.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
Ascend Medical logo

Ascend Medical

6.5
★★★☆☆3.3/5

Best for: coaching bundled into the price rather than sold separately

Visit Ascend Medical →
VS
MANÜ Telehealth logo

MANÜ Telehealth

6.9
★★★★☆3.5/5

Best for: semaglutide at $120/month, 44% below the typical price

Visit MANÜ Telehealth →

If you are choosing between Ascend Medical and MANÜ Telehealth, the first difference is cost: MANÜ Telehealth is $2.29 a month cheaper at the entry price. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. MANÜ Telehealth leads our six-part score, 6.9 to 6.5.

Ascend Medical vs MANÜ Telehealth price

MANÜ Telehealth is the cheaper way in: $120 a month against $122.29 a month at Ascend Medical. That is $2.29 less each month (2% lower), or about $27.48 over a year of treatment.

Drug by drug: Semaglutide is cheaper at MANÜ Telehealth ($120 a month vs $122.29 a month); tirzepatide is cheaper at Ascend Medical ($130.45 a month vs $150 a month).

Medications and formats

Both sell semaglutide and tirzepatide.

On format they match: each offers compounded injections.

Where each one treats patients

Ascend Medical lists 2 states, and MANÜ Telehealth does not publish where it ships.

Pricing

Ascend Medical

Compounded semaglutide, starting dose, billed $225 every 8 weeksCompounded
$122.29/mo
semaglutide

Advertised as $225 a month. The seller bills $225 every 56 days, which works out at $122.29 per calendar month. The figure here is the calculated one. This is the starting dose. Higher doses may cost more.

Compounded tirzepatide, starting dose, billed $240 every 8 weeksCompounded
$130.45/mo
tirzepatide

Advertised as $240 a month. The seller bills $240 every 56 days, which works out at $130.45 per calendar month. The figure here is the calculated one. This is the starting dose. Higher doses may cost more.

MANÜ Telehealth

Standard titrationCompounded
$150/mo
tirzepatide
Standard titrationCompounded
$120/mo
semaglutide

What each price covers

Ascend Medical's price also covers coaching, which MANÜ Telehealth does not claim.

MANÜ Telehealth's price also covers the clinician visit, the medication itself and shipping, which Ascend Medical does not claim.

Ascend Medical is silent on the clinician visit, the medication itself, shipping and lab work.

MANÜ Telehealth is silent on lab work and coaching.

That matters most for the drug: unless Ascend Medical confirms otherwise, budget for medication on top of its listed price.

Ascend Medical

Covered by the monthly price

Medication

Not stated

Clinician visits

Not stated

Shipping

Not stated

Lab work

Not stated

Coaching

In the price

MANÜ Telehealth

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

Where each one scores higher

Overall, MANÜ Telehealth scores 6.9 and Ascend Medical 6.5 out of 10.

Ascend Medical is stronger on user experience (8.0 vs 3.0) and trust & safety (8.5 vs 4.0).

MANÜ Telehealth is stronger on value (8.7 vs 3.0), accessibility (5.0 vs 2.3) and support (7.0 vs 5.0).

Effectiveness is within half a point.

How we score

Ascend Medical

6.5/10

Overall

MANÜ Telehealth

6.9/10

Value25%

3.0A
vs
B
8.7

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
3.0

Trust & Safety15%

8.5A
vs
B
4.0

Accessibility10%

2.3A
vs
B
5.0

Support10%

5.0A
vs
B
7.0

FDA warning letters

Neither Ascend Medical nor MANÜ Telehealth has an FDA warning letter on record with us.

Features & Coverage

FeatureAscend MedicalMANÜ Telehealth
Starting Price$122.29/mo✓$120/mo
Features8 features8 features
States Available2Not disclosed
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA Warning LettersNoneNone

About Ascend Medical

Which GLP-1 it uses, whether that drug is branded or compounded, and what any of it costs are all absent; you would have to contact the practice. Ascend Medical works virtual-first on whole-person primary care, and Medical Weight Loss is one line among health coaching, diabetes care, men's and women's health, mental health and primary care. Licensed MDs, DOs, NPs and PAs staff it. Only Georgia and Texas residents can currently sign up. Do not confuse it with Ascend Vitality, a different company.

Read our full Ascend Medical review →

About MANÜ Telehealth

GLP-1s are advertised from about $4 to $5/day. MANÜ Telehealth sells compounded weight loss medication, injectable tirzepatide and semaglutide, with MIC Ultraburn and NAD+ injections offered as add-ons; US 503A pharmacies do the compounding. The US platform keeps the process 100% online, with monthly check-ins, board-certified physicians, free shipping and no insurance required. Which states are served can change; signup confirms it. Hormone optimization gets a mention but is not the primary focus. Compounded medications here are not FDA-evaluated.

Read our full MANÜ Telehealth review →

Pros & Cons

Ascend Medical

What we like

  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes coaching
  • We found no FDA warning letters issued to Ascend Medical

Watch-outs

  • Serves only 2 states, so check that yours is one of them
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

MANÜ Telehealth

What we like

  • Tirzepatide costs $150 a month, 40% below the $250 median for compounded tirzepatide across the sellers we compare
  • Semaglutide costs $120 a month, 35% below the $185 median for compounded semaglutide across the sellers we compare
  • The monthly price includes the medication, clinician visits and shipping
  • We found no FDA warning letters issued to MANÜ Telehealth

Watch-outs

  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: MANÜ Telehealth

MANÜ Telehealth wins this one, 6.9 to 6.5, above all for semaglutide at $120/month, 44% below the typical price. It also costs $2.29 less each month than Ascend Medical. Ascend Medical fits better if coaching bundled into the price rather than sold separately is your priority.

Choose Ascend Medical if…

You want coaching bundled into the price rather than sold separately and an opening price near $122.29 a month.

Choose MANÜ Telehealth if…

You want semaglutide at $120/month, 44% below the typical price and an opening price near $120 a month.

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Enhance MD

Knowing which pharmacy fills the vial: it names Tru Meds Rx

6.1

DudeMeds

Compounded semaglutide at $175/month

7.8

Oak

Semaglutide at $119/month, 37% below the typical price

Ascend Medical vs MANÜ Telehealth: FAQ

MANÜ Telehealth. It starts at $120 a month; Ascend Medical starts at $122.29 a month, $2.29 more per month.
Yes, both sell semaglutide and tirzepatide.
Ascend Medical lists 2 states; MANÜ Telehealth does not publish where it ships. Confirm your state before paying.
Only Ascend Medical includes coaching. Only MANÜ Telehealth includes the clinician visit, the medication itself and shipping.
Ascend Medical has none. MANÜ Telehealth has none.
No. Neither Ascend Medical nor MANÜ Telehealth pays us anything.

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