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Arc-1 vs LifeRx.md

Arc-1 and LifeRx.md both sell semaglutide and tirzepatide; this is how their prices, coverage and records differ.

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By Ruth Calder · Enforcement Editor
Editorially reviewed (not clinically reviewed). Not medical advice · How we verify contentLast reviewed
Arc-1 logo

Arc-1

7.5
★★★★☆3.8/5

Best for: compounded semaglutide at $199.99/month

Visit Arc-1 →
VS
LifeRx.md logo

LifeRx.md

6.2
★★★☆☆3.1/5

Best for: coverage in all 50 states, which most sellers will not confirm

Visit LifeRx.md →

If you are choosing between Arc-1 and LifeRx.md, price alone will not settle it. Both prescribe semaglutide and tirzepatide, so moving from one to the other would not change your drug. Arc-1 leads our six-part score, 7.5 to 6.2.

Arc-1 vs LifeRx.md price

Arc-1 and LifeRx.md start at within a dollar of each other ($199.99 and $200 a month), so the entry price does not separate them. Look at what each price covers and at the per-drug prices below.

Drug by drug: Semaglutide costs the same at both, $199.99 a month; tirzepatide is cheaper at Arc-1 ($199.99 a month vs $275 a month).

Medications and formats

Both sell semaglutide and tirzepatide.

On format they match: each offers compounded injections.

Where each one treats patients

Arc-1 does not publish where it ships, and LifeRx.md lists 50 states.

Pricing

Arc-1

Compounded Semaglutide 0.5mgCompounded
$199.99/mo
semaglutide
Compounded Semaglutide 1mgCompounded
$249.99/mo
semaglutide
Compounded Semaglutide 2.5mgCompounded
$549.99/mo
semaglutide
Compounded Tirzepatide 2.5mgCompounded
$199.99/mo
tirzepatide
Compounded Tirzepatide 5mgCompounded
$249.99/mo
tirzepatide
Compounded Tirzepatide 7.5mgCompounded
$399.99/mo
tirzepatide

LifeRx.md

all doses (5-week supply)Compounded
$200/mo
semaglutide
all doses (5-week supply)Compounded
$275/mo
tirzepatide

What each price covers

Arc-1's price also covers the clinician visit, the medication itself and shipping, which LifeRx.md does not claim.

Arc-1 is silent on lab work and coaching.

LifeRx.md does not say what its price includes.

That matters most for the drug: unless LifeRx.md confirms otherwise, budget for medication on top of its listed price.

Arc-1

Covered by the monthly price

Medication

In the price

Clinician visits

In the price

Shipping

In the price

Lab work

Not stated

Coaching

Not stated

LifeRx.md

Inclusions not disclosed.

Where each one scores higher

Overall, Arc-1 scores 7.5 and LifeRx.md 6.2 out of 10.

Arc-1 is stronger on value (6.6 vs 4.4), user experience (8.0 vs 2.5), trust & safety (6.5 vs 5.0) and support (7.0 vs 5.0).

LifeRx.md is stronger on accessibility (10.0 vs 5.0).

Effectiveness is within half a point.

How we score

Arc-1

7.5/10

Overall

LifeRx.md

6.2/10

Value25%

6.6A
vs
B
4.4

Effectiveness25%

10.0A
vs
B
10.0

User Experience15%

8.0A
vs
B
2.5

Trust & Safety15%

6.5A
vs
B
5.0

Accessibility10%

5.0A
vs
B
10.0

Support10%

7.0A
vs
B
5.0

FDA warning letters

Neither Arc-1 nor LifeRx.md has an FDA warning letter on record with us.

Features & Coverage

FeatureArc-1LifeRx.md
Starting Price✓$199.99/mo$200/mo
Features3 features✓8 features
States AvailableNot disclosed50
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted—✓ Yes
FDA Warning LettersNoneNone

About Arc-1

Arc-1 does not bill monthly. Doses get bought one at a time: compounded semaglutide from $249.99, compounded tirzepatide from $299.99. The rest of this longevity-focused catalog runs to metformin, sermorelin, rapamycin, NAD+, B12, and ED medication.

Read our full Arc-1 review →

About LifeRx.md

The dose can climb without the price moving. A five-week supply of the compounded GLP-1 semaglutide costs about $200 and compounded tirzepatide about $275, flat. Around those sit roughly $30 of shipping on each order, a $49.95 first consult and $25 follow-ups, putting the real monthly figure near $255. State-licensed 503A pharmacies do the filling and a video consult is required to start. LifeRx.md carries LegitScript certification, reaches all 50 states, and takes HSA and FSA.

Read our full LifeRx.md review →

Pros & Cons

Arc-1

What we like

  • Semaglutide costs $199.99 a month, close to the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $199.99 a month, 20% below the $250 median for compounded tirzepatide across the sellers we compare
  • Shows its price before the medical questionnaire, so you can compare it without handing over health information
  • The monthly price includes the medication, clinician visits and shipping
  • We found no FDA warning letters issued to Arc-1

Watch-outs

  • Confirm it serves your state before you start the intake
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

LifeRx.md

What we like

  • Semaglutide costs $200 a month, close to the $185 median for compounded semaglutide across the sellers we compare
  • Tirzepatide costs $275 a month, close to the $250 median for compounded tirzepatide across the sellers we compare
  • Serves all 50 states
  • We found no FDA warning letters issued to LifeRx.md
  • A live video visit with a clinician is required before a prescription, which is slower than a form and is the more careful intake

Watch-outs

  • You only see a price after finishing the medical intake, so you cannot compare costs before sharing health information
  • Ask which pharmacy fills the prescription before you pay, so you can check its license
  • Its semaglutide and tirzepatide are compounded rather than FDA-approved, so they have not been reviewed by the agency for safety, effectiveness or manufacturing quality

Our Verdict

Winner: Arc-1

Arc-1 wins this one, 7.5 to 6.2, above all for compounded semaglutide at $199.99/month. LifeRx.md fits better if coverage in all 50 states, which most sellers will not confirm is your priority.

Choose Arc-1 if…

You want compounded semaglutide at $199.99/month and an opening price near $199.99 a month.

Choose LifeRx.md if…

You want coverage in all 50 states, which most sellers will not confirm and an opening price near $200 a month.

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Arc-1 vs LifeRx.md: FAQ

Neither on the entry price: Arc-1 and LifeRx.md both start at about $200 a month. The difference is in what the price includes.
Yes, both sell semaglutide and tirzepatide.
Arc-1 does not publish where it ships; LifeRx.md lists 50 states. Confirm your state before paying.
Only Arc-1 includes the clinician visit, the medication itself and shipping.
Arc-1 has none. LifeRx.md has none.
No. Neither Arc-1 nor LifeRx.md pays us anything.

Or see the full category ranking.